A5013558321- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Animal Disease Management and Epidemiology
- Hepatitis Viruses Studies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Vector-Borne Animal Diseases
- Viral Infections and Vectors
- Antimicrobial Peptides and Activities
- Cytomegalovirus and herpesvirus research
- Rabies epidemiology and control
- Toxoplasma gondii Research Studies
- Brucella: diagnosis, epidemiology, treatment
- Liver Disease and Transplantation
- Animal testing and alternatives
- Salmonella and Campylobacter epidemiology
- Viral Infections and Immunology Research
- Identification and Quantification in Food
- Wheat and Barley Genetics and Pathology
- Biochemical and Structural Characterization
- Escherichia coli research studies
- Microbial infections and disease research
- T-cell and Retrovirus Studies
- Bat Biology and Ecology Studies
Istituto Zooprofilattico Sperimentale del Mezzogiorno
2014-2025
Ministero della Salute
2015-2020
University of Naples Federico II
2003-2008
Utrecht University
2004
Feline coronavirus (FCoV) is an alphacoronavirus (αCoV) that causes moderate or chronic asymptomatic infection in cats. However, a single infected cat, FCoV can modify its cellular tropism by acquiring the ability to infect macrophages, resulting development of feline infectious peritonitis (FIP). In this context, restrain impact infection, scientific research has focused attention on antiviral therapies involving novel mechanisms action. Recent studies have demonstrated aryl hydrocarbon...
Abstract In humans as well in animals, the toxic contaminant 2,3,7,8-tetrachlorodibenzo- p- dioxin (TCDD) stimulates immunosuppression and increases responsiveness to infectious diseases. The relationship between environmental contaminants different diseases, including COVID-19, has been described. Nevertheless, reports about potential impact of TCDD on coronaviruses (CoVs) are limited. this study, (0–100 pg/mL) was assessed during infection vitro with canine coronavirus (CCoV-II), alphaCoV...
To assess the quality of shellfish harvest areas, bivalve mollusk samples from three coastal areas Campania region in Southwest Italy were evaluated for viruses over a three-year period (2015-2017). Screening 289 farms and other locations by qPCR RT-qPCR identified hepatitis A virus (HAV; 8.9%), norovirus GI (NoVGI; 10.8%) GII (NoVGII; 39.7%), rotavirus (RV; 9.0%), astrovirus (AsV; 20.8%), sapovirus (SaV; 18.8%), aichivirus-1 (AiV-1; 5.6%), adenovirus (AdV, 5.6%). Hepatitis E (HEV) was never...
Canine coronavirus (CCoV) can produce a self-limited enteric disease in dogs but, because of notable biological plasticity coronaviruses (CoVs), numerous mutations as well recombination events happen leading to the emergence variants often more dangerous for both animals and humans. Indeed, new canine-feline recombinant alphacoronaviruses, recently isolated from humans, highlight cross-species transmission potential CoVs. Consequently, effective antiviral agents are required treat CoV...
Hepatitis E virus (HEV) is a zoonotic pathogen with worldwide distribution, and infects several mammalian species, including pigs wild boars, which are recognized as its natural reservoirs. The causes usually self-limiting liver disease mortality rate generally below 1%, although rates of 15%–25% have been recorded in pregnant woman. Chronic infections can also occur. prevalence HEV has extensively studied boars northern Italy, where intensive pig herds predominantly located. In contrast,...
In recent years, porcine circovirus (PCV) infection has been documented as an important and emerging health concern for livestock wildlife worldwide. The purpose of the present study was to assess molecular prevalence PCV-2 PCV-3 clarify epidemiological role wild boars in circulation this virus Campania, Southern Italy. For purpose, samples from several organs were collected during hunting season 2017-2018 148 Campania region. Quantitative real-time PCR used detection quantification genomes....
From 2019 to 2021, a retrospective molecular study was conducted in the Campania region (southern Italy) determine prevalence of viral diseases domestic cats. A total 328 dead animals were analyzed by Real-Time PCR for presence feline panleukopenia virus (FPV), leukemia (FeLV), enteric coronavirus (FCoV), rotavirus (RVA), herpesvirus type 1 (FHV-1), and calicivirus (FCV). The possible SARS-CoV-2 also investigated PCR. cats included this specifically sourced referred local veterinarians...
ABSTRACT We tested 413 water buffalo cows (142 cases and 271 controls) for the presence of anti- Brucella abortus antibodies (by skin test, agglutination complement fixation test) Nramp1 genotype capillary electrophoresis). Four alleles ( Nramp1A , - B C D ) were detected in 3′ untranslated region gene. The BB was represented among only controls, providing evidence that this confers resistance to . monocytes from (resistant) subjects displayed a higher basal level mRNA lower number viable...
A Flavivirus survey on 183 hunting dogs was conducted in Campania region, Southern Italy. The seroprevalence value of 40.43% (74/183, 95% confidence intervals [CIs] 33.37–47.49) detected our study using a competitive enzyme-linked immunosorbent serologic assay (cELISA) proves considerable level exposition these animals. Among the 74 cELISA-positive sera, seroneutralization (SN) test showed that 24 sera resulted positive for Usutu virus with an overall prevalence 13.11% (24/183) (95% CI...
Aujeszky's disease (AD, pseudorabies) is a viral of suids caused by Suid Herpesvirus 1 (SHV-1) also referred as virus (ADV) or Pseudorabies (ADV). Domestic pig and Wild boar (Sus scrofa) are the natural host, but many species can be infected with ADV. The aim our study was to evaluate seroprevalence AD in wild hunted Campania Region, during 2016-2017 hunting season. A total 503 serum samples from boars provinces Region (Southern Italy) were collected tested for antibody against ADV using an...
This study aims to investigate the presence of canine distemper virus (CDV) infection in 949 autochthonous or illegally imported dogs from Southern Italy, over a period eight years (2014-2021). CDV RNA was detected 6.8% (65/949) animals tested, with no detection sampled 2020-2021. The frequency higher (19/103, 18.3%) respect stray (27/365, 7.4%) and household (19/481, 3.9%). On sequence phylogenetic analyses selected strains, analyzed viruses belonged Arctic clade, which has already been...
Abstract Background Pseudorabies is an infection of domestic and wild pigs that has occasionally been reported in dogs with fatal encephalitis. Hunting are predisposed to pseudorabies exposure due incorrect practices (administration raw infected meat) or close contact boars. This study described outbreak two hunting the Campania region, southern Italy. Case presentation Two were hospitalized after a trip, fever, itching, self-inflicted lesions. Laboratory tests showed mild anemia marked...
Bovine herpesvirus type-1 (BoHV-1) is a widespread pathogen that provokes infectious rhinotracheitis and polymicrobial infections in cattle, resulting serious economic losses to the farm animal industry trade restrictions. To date, non-toxic active drugs against BoHV-1 are not available. The exploitation of bioactive properties microbial products great pharmaceutical interest. In fact, fungi promising source novel with broad spectrum activities functions, including antiviral properties....
Systematic wildlife surveillance is important to aid the prevention of zoonotic infections that jeopardize human health and undermine biodiversity. Toxoplasma gondii an opportunistic protozoan can infect all endothermic vertebrates, causing severe disease in immunocompromised humans cases congenital transmission. Humans be infected by ingestion raw meat containing bradyzoites or water contaminated oocysts. In our study, we assessed potential circulation wild mammals performing Campania...