- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Antifungal resistance and susceptibility
- Nail Diseases and Treatments
- biodegradable polymer synthesis and properties
- Microplastics and Plastic Pollution
- Yeasts and Rust Fungi Studies
- Nanocomposite Films for Food Packaging
- Microbial Community Ecology and Physiology
- Plant Pathogens and Resistance
- Ocular Infections and Treatments
- Phytoplasmas and Hemiptera pathogens
- Antimicrobial agents and applications
- Actinomycetales infections and treatment
- Pragmatism in Philosophy and Education
- Studies on Chitinases and Chitosanases
- Wittgensteinian philosophy and applications
- Educational Technology in Learning
- Gut microbiota and health
- Cinema History and Criticism
- demographic modeling and climate adaptation
- Protist diversity and phylogeny
- Healthcare Systems and Technology
- Nematode management and characterization studies
- Cytokine Signaling Pathways and Interactions
Universitat de Miguel Hernández d'Elx
2014-2025
Weatherford College
2024
Hospital Universitari Sant Joan D'Alacant
2024
Instituto de investigación sanitaria y biomédica de Alicante
2023
Universidad Complutense de Madrid
2019
University of Milan
2006
Istituti di Ricovero e Cura a Carattere Scientifico
2006
University of Alicante
1993-1997
Until recently, Cryptococcus gattii infections occurred mainly in tropical and subtropical climate zones. However, during the past decade, C. humans animals Europe have increased. To determine whether were acquired from an autochthonous source or associated with travel, we used multilocus sequence typing to compare 100 isolates (57 40 human patients, 22 environment, 21 animals) 191 around world. Of 57 patient isolates, 47 (83%) obtained since 1995. Among 24 (60%) probably infection outside...
In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total 302 sites located 12 countries were sampled, 6436 samples from 3765 trees collected 5% found be colonized by cryptococcal yeasts. isolated 177 13. 27% Ceratonia, 10% Olea, Platanus Prunus a lower percentage other tree genera. The 13 isolates five Eucalyptus, four two Pinus Olea trees. distributed all around whereas...
Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and neoformans species complexes. After more than 15 years molecular genetic phenotypic studies much debate, proposal for taxonomic revision was made.
Background: Characterizing aerosols produced by SARS‐CoV‐2 patients is crucial for understanding disease transmission. The appearance and dispersal patterns of viral particles in airborne samples are not yet well understood. Knowing what look like just before they pass from one person to another can provide valuable insights into the mechanism transmission through air. Methods: Samples upper respiratory tract environmental were collected 39 SARS‐CoV‐2–positive at different stages symptom...
During a European Confederation of Medical Mycology (ECMM) prospective survey cryptococcosis in Europe (from July 1997 to December 1999) 655 cases were reported from 17 countries; 565 the completed questionnaires evaluable. Cryptococcosis was associated with HIV infection 77% (range 57.5-94%). Assessment laboratory data highlighted lack defined standard procedures for diagnosis cryptococcosis: antigen test not usually used screening, disease mainly recognised when meningitis occurred (65%...
Recent Cryptococcus gattii infections in humans and animals, including several outbreaks goats, were the basis of this environmental survey six provinces Spain. A total 479 samples from 20 tree species studied. was found for first time autochthonous Mediterranean trees Fourteen isolates pathogen obtained seven three different species: 12 carob (Ceratonia siliqua), one stone pine (Pinus halepensis) another eucalyptus (Eucalyptus camaldulensis). All C. genotype AFLP4/VGI mating type alpha, to...
ABSTRACT We report the first case of human cryptococcosis due to Cryptococcus neoformans var. gattii described in our country, which was presented as brain cryptococcoma an immunocompetent patient. An extensive sampling patient's environment carried out find source infection.
Fundamental niche prediction of Cryptococcus neoformans and gattii in Europe is an important tool to understand where these pathogenic yeasts have a high probability survive the environment therefore identify areas with risk infection. In this study, occurrence data for C. were compared by MaxEnt software several bioclimatic conditions as well soil characteristics land use. The results showed that distribution can be predicted along Mediterranean coast. analysis variables its limited low...
A domestic ferret (Mustela putorius furo) was presented with lymphadenopathy and acute bilateral blindness. Cytologic evaluation biopsy of an affected lymph node revealed pyogranulomatous lymphadenitis intralesional yeast consistent Cryptococcus sp. Subsequent studies demonstrated gattii serotype B VGI/AFLP4 as the causative agent. The treated fluconazole prednisone. After one month therapy, improvement clinical symptoms detected although blindness persisted. Seven months after presentation,...
This study analyzes the relationship between mycobiome of Lower Respiratory Tract (LRT) and fungi in domestic environment. Samples studied consisted Broncho-Alveolar Lavage (BAL) from 45 patients who underwent bronchoscopy for different diagnostic purposes, dust air houses (ENV) 20 them (44.4%). Additionally, five bronchoscopes (BS) were also analyzed negative controls included every procedure. All samples processed DNA extraction cultures, which performed Sabouraud Dextrose Potato Agar. The...
We report a new fungus as an agent of fungal keratitis in diabetic woman. The etiology was established by classic microbiology and PCR following 3 months antibacterial therapy. morphological features the isolate sequence analysis internal transcribed spacer region indicate species Pyrenochaeta (Coelomycetes).
The antifungal drug susceptibility of 70 Cryptococcus neoformans isolates obtained in Spain from 1994 to 1996 (23 isolates) and 1997 2005 (47 was investigated. MICs fluconazole, itraconazole voriconazole were determined by the modified Clinical Laboratory Standards Institute (CLSI; formerly National Committee for Standards) broth microdilution method. MIC(50) MIC(90) did not change significantly 2005. fluconazole remained stable decreased 2 log(2) dilution collected We conclude that vitro...
Mycetoma is one of the six Neglected Tropical Diseases that are prevalent in Turkana County (northwest Kenya). The aim study was to estimate prevalence mycetoma county, as well describe main causative agents involved disease using methods affordable locally. Based on data collected by team cooperative medicine Cirugia en (Surgery Turkana), a specific for started during 16 th humanitarian campaign February 2019. Patients with suspected were studied at Lodwar Referral Hospital (LCRH). After...