- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Yeasts and Rust Fungi Studies
- Infectious Diseases and Mycology
- Mycotoxins in Agriculture and Food
- Plant Disease Resistance and Genetics
- Digital Imaging for Blood Diseases
- Bacterial Identification and Susceptibility Testing
- Helminth infection and control
- Mycobacterium research and diagnosis
- COVID-19 diagnosis using AI
- Microbial infections and disease research
- Mosquito-borne diseases and control
- Plant Pathogens and Resistance
- Diverse Scientific Research Studies
- Vasculitis and related conditions
- Body Image and Dysmorphia Studies
- Dermatological diseases and infestations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Multicomponent Synthesis of Heterocycles
- Enterobacteriaceae and Cronobacter Research
- Essential Oils and Antimicrobial Activity
Université de Montpellier
2012-2023
Inserm
2015-2023
Institut de Recherche pour le Développement
2012-2023
Recherches Translationnelles sur le VIH et les Maladies Infectieuses
2014-2023
Agropolis International
2019-2023
Bipar
2021
Institut de Recherches Médicales et d’Etudes des Plantes Médicinales
2014
Hôpital Charles-Nicolle
2012
Sciences pour L’Œnologie
2005-2010
Malaria remains a global health problem, with 247 million cases and 619,000 deaths in 2021. Diagnosis of
In order to elucidate the distribution of Cryptococcus neoformans and C. gattii in Mediterranean basin, an extensive environmental survey was carried out during 2012-2015. A total 302 sites located 12 countries were sampled, 6436 samples from 3765 trees collected 5% found be colonized by cryptococcal yeasts. isolated 177 13. 27% Ceratonia, 10% Olea, Platanus Prunus a lower percentage other tree genera. The 13 isolates five Eucalyptus, four two Pinus Olea trees. distributed all around whereas...
Cryptococcosis is a major fungal disease caused by members of the Cryptococcus gattii and neoformans species complexes. After more than 15 years molecular genetic phenotypic studies much debate, proposal for taxonomic revision was made.
Background Ivermectin is known to cause severe encephalopathies in subjects infected with loiasis, an endemic parasite Sub-Saharan Africa (SSA). In addition, case reports have described ivermectin-related serious adverse drug reactions (sADRs) such as toxidermias, hepatic and renal disorders. The aim of this study was identify suspected sADRs reported after ivermectin administration VigiBase, the World Health Organization’s global individual safety database analyze their frequency relative...
ABSTRACT In recent years, Geosmithia argillacea has been increasingly reported in humans and animals can be considered an emerging pathogen. The taxonomy of was recently studied, related species were transferred to the new genus Rasamsonia . diversity among a set strains, including 28 clinical antifungal susceptibility profiles generated. Data obtained from morphological studies phylogenetic analyses internal transcribed spacer (ITS) partial β-tubulin calmodulin sequences revealed presence...
Abstract Fungal flora in coastal/inland beach sand and recreational water is a neglected field of study, despite its potential impact on human health. A joint ISHAM/ECMM working group was formed 2019 with the task to set up vast international initiative aimed at studying fungal contamination beaches bathing waters. Here we review importance topic, list main results achievements from 12 scientific publications. exists different levels genera most frequently found were Aspergillus spp.,...
ABSTRACT Infections due to Candida spp. are frequent, particularly in immunocompromised and intensive care unit patients. Antifungal susceptibility tests now required optimize antifungal treatment given the emergence of acquired resistance some species. An automated method, Vitek 2 system (VK2), was evaluated. VK2 compared CLSI broth microdilution reference method Etest procedure. For this purpose, 205 clinical isolates spp., including 11 different species, were tested for fluconazole,...
Fundamental niche prediction of Cryptococcus neoformans and gattii in Europe is an important tool to understand where these pathogenic yeasts have a high probability survive the environment therefore identify areas with risk infection. In this study, occurrence data for C. were compared by MaxEnt software several bioclimatic conditions as well soil characteristics land use. The results showed that distribution can be predicted along Mediterranean coast. analysis variables its limited low...
The genotypes of 52 strains Aspergillus fumigatus isolated from 12 patients with invasive aspergillosis were investigated using three typing methods (random amplified polymorphic DNA, sequence-specific DNA polymorphism, and microsatellite polymorphism) combined multilocus enzyme electrophoresis. Isolates hospitalized in different geographic areas (Lyon, France; Grenoble, Milan, Italy). In each case, the genetic polymorphism several colonies (two to five) within first respiratory clinical...
We have investigated the genotype at 14 enzyme-encoding loci in 275 isolates of pathogenic yeast Candida albicans sampled from 42 HIV-positive patients (all but one with AIDS) Abidjan (Côte d’Ivoire). separately analyzed following variables: patient, residence, age, gender, T cell count, hospitalization (yes or no), drug treatment, date sampling, multilocus genotype, and serotype. The most important factors contributing to genetic variability C. are individual patient gender. Our data...
Minor species of the Candida albicans complex may cause overestimation epidemiology C. albicans, and misidentifications could mask their implication in human pathology. Authors determined occurrence minor (C. africana, dubliniensis stellatoidea) among Yaoundé HIV-infected patients, Cameroon. Stool, vaginal discharge, urine oropharyngeal samples were analysed by mycological diagnosis. Isolates identified conventional methods mass spectrometry (MS; carried out matrix-assisted laser...
It seems that S. cerevisiae, which was thought for about 30 years to be a nonpathogenic yeast, should now considered an opportunistic pathogen. In this study, we estimated the discrimination ability of microsatellite sequence amplification technique within sample clinical and reference cerevisiae strains boulardii strains.
Genetic diversity analyses were performed by sero-genotyping and multi-locus sequence typing on 252 cryptococcal isolates from 13 HIV-positive Ivorian patients followed-up for meningitis. Antifungal susceptibility according to the CLSI M27A3 method. The majority (67.8%) of belonged Cryptococcus neoformans (serotype A) species complex, with 93% being VNI 7% VNII. deuterogattii VGII B) represented 16.7% strains, while C. neoformans/C. deneoformans VNIII AD) hybrids accounted 15.1% strains. One...
Mycoses caused by Candida and Cryptococcus species, associated with the advent of antifungal drug resistance have emerged as major health problems. Improved control measures innovative therapies are needed. This paper describes results from screening bio-guided fractionated extracts alone combinations Terminalia catappa, mantaly Monodora tenuifolia harvested in Cameroon. Crude ethanolic, hydro-ethanolic aqueous fractions were screened for activity against isolates C. albicans, glabrata,...
Cryptococcal meningitis is a severe opportunistic infection in HIV-infected patients. In Ivory Coast, despite the availability of antiretroviral treatment (ART), this still prevalent. The study investigates genetic diversity 363 clinical isolates Cryptococcus from 61 Ivorian HIV-positive patients, occurrence mixed infections and vitro antifungal susceptibility isolates. Serotyping was performed via LAC1 CAP64 gene amplification. Genotyping using phage M13 core (GACA)4 (GTG)5 primers...
Fungi belonging to the Cryptococcus genus and related genera (Filobasidium, Holtermanniella, Naganishia, Papiliotrema, Solicoccozyma, Vishniacozyma) are encapsulated yeasts found in either environment or animal sources. However, precise biotopes of most species remain poorly defined. To assess whether wild birds from southern France can carry spread pathogenic (i.e., C. neoformans gattii complexes), as well lesser-studied (non-neoformans/gattii former spp.), 669 89 received for care over a...
ABSTRACT This study aimed to assess the interlaboratory reproducibility at four university hospital laboratories in southeast region of France Etest technique for determination caspofungin (CAS) and amphotericin B (AMB) MICs compare it CLSI broth microdilution reference method. Consecutive clinical yeast isolates ( n = 198) were included study. AMB CAS read 24 48 h. Interlaboratory was estimated by using (i) an intraclass correlation coefficient (ICC), (ii) essential agreement (EA), (iii)...