A5052790042- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Nail Diseases and Treatments
- Infectious Diseases and Mycology
- Pneumocystis jirovecii pneumonia detection and treatment
- Indoor Air Quality and Microbial Exposure
- Neutropenia and Cancer Infections
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tuberculosis Research and Epidemiology
- Mycotoxins in Agriculture and Food
- Fungal Biology and Applications
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Oral microbiology and periodontitis research
- Pneumonia and Respiratory Infections
- Antimicrobial Resistance in Staphylococcus
- Sinusitis and nasal conditions
- Adrenal Hormones and Disorders
- Probiotics and Fermented Foods
- Peptidase Inhibition and Analysis
- Oral Health Pathology and Treatment
- Reproductive tract infections research
- Respiratory and Cough-Related Research
- Cystic Fibrosis Research Advances
University of Manchester
2015-2024
Manchester University NHS Foundation Trust
2017-2024
Manchester Academic Health Science Centre
2013-2023
Wythenshawe Hospital
2011-2023
NIHR Manchester Biomedical Research Centre
2021-2023
Genomics (United Kingdom)
2022
National Health Service
2021
Waitemata District Health Board
2020
University Foundation
2019
European Society of Clinical Microbiology and Infectious Diseases
2018
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare-associated infections. We report that this highly virulent the capacity to form antifungal resistant biofilms sensitive disinfectant chlorhexidine in vitro.
Resistance to azole antifungal drugs in Aspergillus fumigatus is now a major clinical problem some locations. Here we update our previous experience with data from 2008–09. We tested all A. isolates submitted the Mycology Reference Centre Manchester 2008 and 2009 for susceptibility itraconazole, voriconazole posaconazole. undertook CYP51A sequencing most of azole-resistant isolates. Of 230 isolates, 64 (28%) were resistant. In 2009, 14% 20% patients had resistant respectively. During this...
Overgrowth of oral yeast is a common problem among the elderly. Probiotic bacteria are known to inhibit growth pathogenic microbes. We tested hypothesis that cheese containing probiotic can reduce prevalence Candida. During this 16-week, randomized, double-blind, placebo-controlled study, 276 elderly people consumed daily 50 g either (n = 136) or control 140). The primary outcome measure was high salivary count (>or= 10(4) cfu/mL) analyzed by Dentocult method. decreased in group from 30% 21%...
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for management onychomycosis. document aims (i) offer an appraisal all relevant literature since January 2002, focusing on any key developments; (ii) address important, practical clinical questions relating primary objective, example accurate diagnosis and identification cases, suitable treatment minimize duration disease discomfort; (iii) and, where appropriate, with some health economic...
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also capacity form adherent biofilm communities on range of clinically important substrates. While we have comprehensive understanding how other species resist and respond challenge within the sessile phenotype, our current C. biofilm-mediated lacking. In this study, are first perform transcriptomic analysis temporally developing biofilms, which were shown...