A5088309223- Nutrition and Health in Aging
- Iron Metabolism and Disorders
- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Management of metastatic bone disease
- Gastroesophageal reflux and treatments
- Cardiac Arrhythmias and Treatments
- Intramuscular injections and effects
- Cardiac, Anesthesia and Surgical Outcomes
- Neuroblastoma Research and Treatments
- Acute Lymphoblastic Leukemia research
- Metabolism, Diabetes, and Cancer
- Inflammatory Bowel Disease
- Parkinson's Disease Mechanisms and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Multiple Myeloma Research and Treatments
- Hemoglobinopathies and Related Disorders
- Frailty in Older Adults
- Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Mechanical Circulatory Support Devices
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Jefferson Hospital
2024-2025
Albert Einstein College of Medicine
2025
Einstein Medical Center Philadelphia
2024
Thomas Jefferson University Hospital
2024
Jersey Shore University Medical Center
2024
Morehouse School of Medicine
2024
Translational Research in Oncology
2023
University of Port Harcourt
2022
Breast cancer patients are at risk of acute decompensated heart failure (ADHF) and protein-energy malnutrition (PEM) due to chemoradiation effects or itself. There no existing studies on the impact PEM breast hospitalized for ADHF. This study aims evaluate admitted Using 2020 US National Inpatient Sample (NIS), our analyzed aged 18 older. A multivariate logistic linear regression analysis determined odds ratio various outcomes. The primary outcome was inpatient mortality among ADHF based...
12098 Background: The economic burden of colorectal cancer (CRC), a major cause cancer-related death worldwide, is significant and fueled by extended hospital stays, intensive treatments, expensive end-of-life care, with costs expected to rise as the population ages. While clinical research has established benefits palliative care (PC) in improving patient outcomes, its impact within CRC pathways remains underexplored. This study employs large-scale, propensity-matched cohort analysis...
e24057 Background: Neuroendocrine tumors are slow-growing commonly found in the gastrointestinal tract. Diagnosis is often delayed as patients present either asymptomatically or with non-specific symptoms. Patients neuroendocrine at risk for protein-energy malnutrition (PEM) from treatment surgery and/or chemoradiation cancer itself. Data on impact of this PEM limited. Methods: A retrospective cohort study was conducted using TriNetX platform to compare outcomes between (Cohort 1, N = 2,531)...
e17112 Background: Prostate cancer (PC) is characterized by significant genomic heterogeneity, which drastically impacts its clinical course and therapeutic outcomes. It historically observed that race influences outcome in PC, with disparities between white black communities. These can be partially attributed to biological differences. This elucidates the differences profiling these groups identify molecular pathways affecting PC progression prognosis. Methods: Data analyzed from Memorial...
e17121 Background: Chromosome arm 8q is frequently amplified in prostate cancer, harboring genes that drive tumor progression, therapy resistance, and poor outcomes. Key loci include MYC , which regulates cell proliferation; AR central to cancer biology resistance; RAD21 essential for chromosomal stability. While the prognostic implications of gains have been explored, their role driving racial disparities outcomes remains underexplored. This study investigates chromosome amplification as a...
11041 Background: Breast cancer (BC) patients are at risk for iron deficiency anemia (IDA) due to the effects of chemotherapy on bone marrow and because potential malignant infiltration marrow. Additionally, BC increased heart failure either from chemoradiation myocardium or direct tumor invasion heart. Studies have shown that IDA is associated with worse functional outcomes, hospitalization, mortality in preserved ejection fraction (HFpEF). There limited data impact long-term cardiovascular...
12045 Background: Non-small cell lung carcinoma (NSCLC) predominantly affects older adults (≥65 years), where immune checkpoint inhibitors (ICIs) are a key treatment, especially in those without driver mutations. However, the effect of ICIs on age-related health issues (geriatric syndromes), which impact quality life this population, is unclear. This study aims to investigate geriatric syndromes with NSCLC. Methods: We utilized data from Global Collaborative Network-TrinetX evaluate...
e14014 Background: Renal cell carcinoma, lung breast and melanoma are cancers that commonly metastasize to the brain. Currently, it is unknown what makes a person more likely develop brain metastases. Anemia might be linked with tumor hypoxia, which induces angiogenesis increases aggressiveness. However, unclear how anemia affect risk of metastases in these patients. Methods: We utilized 2024 TriNetX database conducting this retrospective cohort study. identified patients since 2010 using...
Background Colorectal cancer (CRC) poses a significant burden on healthcare systems globally. Sociodemographic factors intricately influence CRC epidemiology, yet their impact inpatient care remains underexplored. This study aimed to assess trends in hospitalization and the effect of sociodemographic outcomes patients.
Autonomic dysfunction in Parkinson's disease (PD) includes cardiovascular dysregulations which may manifest as an increased risk of atrial fibrillation (AF). However, data on the impact PD AF patients is lacking. Our study aimed to investigate differences in-hospital mortality admitted for with underlying versus those without PD.We examined National Inpatient Sample (NIS) database from 2016 2019 hospitalizations a principal diagnosis and secondary diagnosis. The primary outcome was inpatient...
There is a class I indication for immediate angiography and, if indicated, revascularization in patients with out-of-hospital cardiac arrest (OOHCA) presenting STEMI. The role of early coronary OOHCA without STEMI remains unclear. Using the NIS database from January 2015 to December 2020, we examined utilization (coronary within 24 hours index hospitalization) patients, STEMI, initial shockable rhythm (ventricular tachycardia or fibrillation), ages 18-85, prior DNR/DNI, and not drowned...
11160 Background: Lung cancer is the leading cause of related deaths in United States. Patients with advanced lung tend to have varying degrees protein energy malnutrition (PEM), due multiple reasons including cachexia, sarcopenia, and adverse effect chemotherapy. However, impact PEM on clinical outcomes this subgroup needs further exploration. Methods: We utilized 2020 National Inpatient Sample (NIS) Database conducting retrospective cohort study. identified patients using appropriate...
6548 Background: Acute leukemia poses a significant burden to the society and healthcare system. Advances in chemotherapeutics hematopoietic stem cell transplantation (HSCT) have increased survival these patients. Protein energy malnutrition (PEM) frequently complicates clinical picture patients with cancer, however data on impact of PEM acute myeloid lymphoid is limited. Methods: We utilized 2020 National Inpatient Sample (NIS) Database conducting this retrospective cohort study. identified...
12030 Background: The breast cancer patient is at risk of acute decompensated heart failure (ADHF) and protein-energy malnutrition (PEM) either from the effects chemoradiation or primary cancer. There have been several studies on patients with ADHF. However, exact impact concurrent PEM admitted for ADHF unclear. We aim to assess how impacts Methods: examined 2020 US National Inpatient Sample (NIS) explore affects Participants aged 18 older were identified using relevant ICD-10 CM codes. A...
e15531 Background: Patients with colorectal cancer (CRC) commonly present gastrointestinal (GI) bleeding and are at risk of developing protein-energy malnutrition (PEM) either due to effects therapeutic interventions (chemotherapy, immunotherapy, radiation) or primary disease on appetite caloric intake. There several existing studies CRC hemorrhage, however the impact concurrent PEM in-hospital outcomes for patients admitted GI is unclear. Our study aims assess association clinical among...
e16292 Background: Neuroendocrine tumors (NET) affect less than 200,000 (52 per 100,000) of the US population, with malignant well-differentiated gastroenteropancreatic (GEP) NETs accounting for about 65% cases. Owing to its rarity, evidence on factors associated all-cause mortality is limited. To address this gap, study aims identify socio-demographic and clinical in-hospital patients GEP NET. Methods: We analyzed data from 2020 Nationwide Inpatient Sample survey hospitalized Using ICD10...
Introduction: Chest radiation has been well-documented to predispose major adverse cardiac events (MACE). However, preventing radiation-induced is still a research gap. There limited data assessing the preventive value of statins in cardiovascular outcomes and mortality chest radiation-treated cancer patients. This study aimed bridge knowledge Methods: Retrospective propensity-matched analysis lung patients aged 30-75 years treated with TriNetX database. Patients were divided into statin...