Background: Obstructive jaundice is one of the most common symptoms which can be caused by both malignant and benign hepato-biliary-pancreatic diseases.The differences differential diagnostic roles serum CA19-9, total bilirubin (TBIL) especially, ratio CA19-9 to TBIL in these patients have not been well elucidated.This study compared increase-folds 508 cases (MOJ) (BOJ) obstructive patients.Methods: Totally, with pathological results were retrospectively enrolled.342 MOJ, including...

Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular neoplasm with increasing incidence. However, its clinical characteristics remain unclear due to low This study aimed investigate the features of EHE.Patients EHE treated at our institution between January 2000 and June 2018 were enrolled. Data including demographic characteristics, treatment patterns, pathological results, prognosis collected, retrospective database was constructed for analysis.The cohort comprised 33...

Abstract The incidence of papillary thyroid microcarcinoma (PTMC) has increased dramatically in recent years. Compared with central lymph node metastases, lateral neck (LNLN) metastases patients PTMC were less studied. aim the present study is to analyze predicting factors associated LNLN PTMC. A total 3514 underwent surgery at our hospital from January 2017 December 2017, and 936 selected assessed retrospectively. They further divided into 2 groups based on whether existed or not....

Purpose: Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy with relatively early lymphatic metastatic spread. The clinical features of MTC remain controversial owing to the low incidence rate. This study aimed analyze characteristics, prognostic factors, and long-term follow-up MTC. Methods: Medical records patients treated at our hospital between December 2000 November 2020 were reviewed retrospectively. Clinicopathologic analyzed using univariate multivariate analyses....

Although incidental gallbladder cancer (IGBC) diagnosed after laparoscopic cholecystectomy (LC) is not rare, its incidence, management, and prognosis are still unclear controversial. The present study aimed to increase the understanding of IGBC LC in medical community.Patients with treated at our institution between January 2001 December 2018 were enrolled. Data collected included demographic characteristics, treatment pattern, pathological information, prognoses. We compared characteristics...

Objectives . Schwannomas are tumors arising from Schwan cells of the neural sheath. Gastrointestinal schwannomas (GS) rare and easily confused with a heterogeneous group neuroectodermal or mesenchymal neoplasms. The aim present study is to analyze clinicopathological features, surgical management methods, long‐term prognoses GS patients. Methods Between August 2004 July 2019, 51 patients were treated at Peking Union Medical College Hospital. medical records reviewed retrospectively. A...

Intraductal papillary neoplasm of the bile duct (IPNB) is a premalignant that can involve both intrahepatic and extrahepatic ducts. Owing to low incidence confusing nomenclature, its clinicopathological features remain controversial. Additionally, only few studies have reported on long-term prognosis IPNB date. Therefore, present study aimed clarify characteristics IPNB.Medical records patients with treated at our hospital between August 2000 October 2021 were retrospectively reviewed. A...

Abstract Background Neuroendocrine neoplasm (NEN) of the gallbladder is rare. It usually asymptomatic and occurs in older adults. Its clinicopathological characteristics remain controversial, diagnosis treatment strategies are based on models adenocarcinoma. The present study aimed to investigate clinical prognosis NEN. Methods data patients with NEN admitted Peking Union Medical College Hospital was reviewed, a database established for retrospective analysis. Clinicopathological features...

Objective Intraductal papillary neoplasm of the bile duct (IPNB) has been increasingly recognized and reported. However, its clinical features are still controversial because low incidence. In present study, we investigated characteristics IPNB. Methods total, 28 patients with IPNB were treated at our institution from January 2000 to December 2016. Clinical data collected a retrospective accurate database was constructed. Demographic characteristics, perioperative management, prognosis...

Curative resection stands as the sole potential cure for gallbladder cancer (GBC); nevertheless, a dearth of knowledge persists regarding long-term follow-up data and prognostic factors that hinder achieving post-surgery. A retrospective cohort study was conducted by analyzing pathologically confirmed initial resections GBC between 2000 2013 across three Chinese medical centers. The concept observed refers to 10-year survival period devoid any disease recurrence. Employing semiparametric...

The choledochal cyst (CC) is a rare cystic dilatory condition with malignant tendency, which more frequently reported in children. Surgical resection of cysts can significantly decrease the risk malignancy and reduce associated complications. However, CC has been paid lesser attention adults, its surgical parameters have to be dispute. This study aimed report experience treatment an adult suggest appropriate for surgery, including extent excision (complete or not), length Y limb, diameter...

Cholangiocarcinoma (CCA) is an aggressive solid tumour with a 5-year survival rate ranging from 7% to 20%. It is, therefore, urgent identify novel biomarkers and therapeutic targets improve the outcomes of patients CCA. SPRY-domain containing protein 4 (SPRYD4) contains SPRY domains that modulate protein-protein interaction in various biological processes; however, its role cancer development insufficiently explored. This study first SPRYD4 downregulated CCA tissues using multiple public...

Abstract Background Lymph node metastasis (LNM) is prevalent in papillary thyroid microcarcinoma (PTMC) and essential when determining tumor stage prognosis. Positive lateral LNM with negative central defined as skip metastasis. Thyroid carcinoma's risk factors for remain controversial, especially PTMC. This study aimed to determine the clinical features well of among patients Methods We conducted retrospective research PTMC who were subjected treatment at our Hospital between January 2018...

Bile duct cyst (BDC) is a rare congenital biliary malformation with 20% of cases initially diagnosed during adulthood. Although the incidence BDC in adults increasing worldwide, clinical features adult remain unclear. The present study was aimed at characterizing demographic and this disease. We constructed retrospective database analyzed records 106 patients (mean age, 41.0 ± 14.8 years; 18 men (17.0%)) treated our institution from May 2012 to October 2018. Data collected included...

Abstract Background Gallbladder carcinoma (GC) is a rare malignant tumor. Laparoscopic technology has revolutionized the reality of surgery. However, whether laparoscopic surgery suitable for GC not been clarified. We aimed to analyze safety, feasibility, and oncological outcomes in GC. Methods The medical records patients with treated at our hospital between January 2016 December 2021 were retrospectively reviewed. Patients who underwent open compared. Propensity score matched analysis was...

Background. Incidence of biliary tract cancers (BTCs) in China is high, and surgery the only curative option. Preoperative CA19-9 has been identified as a predictor for survival patients with resectable BTCs, but more potential predictors need to be studied. This retrospective study aimed establish prognostic significance CA19-9/TBIL ratio (CTR) BTCs. Methods. A analysis was performed who were diagnosed BTCs received surgical resection between 2013 2018 at PUMCH. Demographic clinical...

To evaluate the treatment of recurrent acute cholangitis with hepatolithiasis.We retrospectively analyzed clinical data patients who were treated in Peking Union Medical College Hospitals emergency department from January 1998 to December 2008.Totally 408 underwent surgery, which 167 received operations and 241 selective after medication interventional treatment. The incidence complications was 6.4% among those 3.2% operations. 30-day mortality rate zero.Along progress percutaneous...

Objective To study the impact of TNM staging (AJCC,7th edition,2010) and modes surgical treatment on prognosis patients with gallbladder cancer.Methods The data 151 primary carcinoma (PCG) treated in our hospital from January 1998 to June 2013 were retrospectively analyzed.Results For stage 0-Ⅰ PCG,survival after radical cholecystectomy was not significantly longer than that simple (x2 =0.820,P =0.365).However,in Ⅱ,those by had better those =4.151,P =0.042).The group superior palliative for...

Objective To study the clinical features of intraductal papillary mucinous neoplasm biliary tract (BT-IPMN) and to analyse diagnostic surgical patterns. Method The data 19 patients with BT-IPMN admitted from Jun. 2012 Jul. 2016 were retrospectively analyzed. Results These (2.3%) came 815 tumors who treated in our institution. There 9 males 10 females. The male female ratio was 1.0∶1.1. mean age 60.6±12.9 years a range 25 78 years. Jaundice (in patients) abdominal discomfort 6...

Abstract Introduction: Incidence of biliary tract cancers (BTCs) in China is high, and surgery the only curative option. Preoperative CA19-9 has been identified as a predictor for survival patients with resectable BTCs, but more potential predictors need to be studied. This retrospective study aimed establish prognostic significance CA19-9/TBIL ratio (CTR) BTCs.Methods: A analysis was performed who diagnosed BTCs received surgical resection between 2013 2018 at PUMCH. Demographic clinical...