A5116719957- Neuroendocrine Tumor Research Advances
- Circular RNAs in diseases
- Lung Cancer Research Studies
- Pancreatic and Hepatic Oncology Research
- MicroRNA in disease regulation
- Cardiovascular Function and Risk Factors
- Cancer-related molecular mechanisms research
- Cardiac Imaging and Diagnostics
- Gestational Trophoblastic Disease Studies
- Neuroblastoma Research and Treatments
- Bone health and treatments
- Parathyroid Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Pharmacological Effects of Natural Compounds
- Cardiac electrophysiology and arrhythmias
- Traditional Chinese Medicine Studies
- Gene expression and cancer classification
- Stroke Rehabilitation and Recovery
- Liver Disease and Transplantation
- Reconstructive Surgery and Microvascular Techniques
- Liver Disease Diagnosis and Treatment
- Dental Implant Techniques and Outcomes
- High Altitude and Hypoxia
- Lung Cancer Treatments and Mutations
- Cardiac Valve Diseases and Treatments
University of Technology Sydney
2025
Tianjin Medical University General Hospital
2008-2024
Mayo Clinic in Florida
2024
WinnMed
2024
Chongqing Medical University
2021-2024
First Affiliated Hospital of Jiangxi Medical College
2024
Nanchang University
2015-2024
First Affiliated Hospital of Xinjiang Medical University
2024
Xinjiang Medical University
2024
Sun Yat-sen University Cancer Center
2023
Abstract Objectives To compare the efficiency and safety of a novel flexible ureteral access sheath (f-UAS) traditional (UAS) during retrograde intrarenal surgery (RIRS). Patients methods Between January 2022 September 2022, total 152 consecutive cases with renal stones underwent RIRS f-UAS. Their outcomes were compared those another undergoing UAS using 1:1 scenario matched-pair analysis, matching parameters including age stone size. The f-UAS is 10-cm-long tube at tip that can follow bends...
Objectives We aimed to determine trends in incidence and survival patients with gastrointestinal neuroendocrine tumors (GI-NETs) from 1977 2016, then analyze the potential risk factors including sex, age, race, grade, Socioeconomic status (SES), site, stage. Methods Data were obtained Surveillance, Epidemiology, End Results Program (SEER) database. Kaplan-Meier analysis, relative rates (RSRs), Cox proportional regression model used evaluate relationship between these prognosis. Compared...
Background Limb allotransplantation is emerging as a promising solution to the loss of limb with development advanced surgical techniques and new, highly effective immunosuppressive agents. Methods We retrospectively reviewed records 15 hand allotransplantations in 12 patients China which were performed from September 1999 May 2008. Results In total, there 1 bilateral 5 unilateral transplantations, 3 2 forearm palm thumb transplantation. The average age recipients was 34 ± 11.3 years (range,...
Abstract Post stroke depression (PSD) is a serious complication of stroke. Brain imaging an important method studying the mechanism PSD. However, few studies have focused on single lesion location. The aim this study was to investigate brain frontal lobe PSD using combined voxel-based morphometry (VBM) and functional magnetic resonance (fMRI). In total, 30 first-time ischemic patients underwent T1 weighted MRI resting-state fMRI scans. Clinical assessments included 24-item Hamilton Rating...
BACKGROUNDRecently, more and studies have demonstrated the pivotal role of programmed death 1/programmed ligand 1 (PD-1/PD-L1) pathway in immune evasion tumors from host system.However, PD-1/PD-L1 gastric neuroendocrine carcinomas (G-NECs) remains unknown. AIMTo investigate expression G-NECs, which occur rarely but are highly malignant clinically defiant. METHODSWe investigated PD-L1 on tumor cells PD-1 + , CD8 FOXP3 T cell infiltration by immunohistochemistry 43 resected G-NEC tissue...
Biliary neuroendocrine neoplasms (NENs) represent <1% of all NENs. The aim this retrospective study is to present the clinical characteristics, management and prognosis profiles 28 biliary NEN patients from a large tertiary center, identify factors related prognosis. Nine tumors originated gallbladder, two extrahepatic bile duct 17 ampulla Vater. One patient was classified as tumor (NET) Grade 1, three were NET 2, 18 graded carcinoma (NEC) 3 six mixed adenoneuroendocrine (MANEC). overall...
Physical exercise is beneficial for the functional recovery of neurons after stroke. It has been suggested that regulates proliferation and differentiation endogenous neural stem cells (NSCs); however, underlying molecular mechanisms are still largely unknown. In present study, aim was to investigate whether physical activates extracellular signal‑regulated kinase (ERK) signaling pathway promote NSCs in rats with cerebral infarction, thereby improving neurological function. Following middle...
RET rearrangements are rare, and occur in 1%-2% of all non-small cell lung cancer (NSCLC) patients. Pralsetinib has a significant anti-tumor effect patients with advanced NSCLC rearrangement. Previous studies have confirmed the efficiency neoadjuvant target therapy for NSCLC. Herein we present case involving female patient who was diagnosed stage IIIA adenocarcinoma harbored KIF5B-RET rearrangement based on next-generation sequencing. Radiologic downstaging indicated after pralsetinib...
To investigate the effects of levocarnitine on cardiac function, urinary albumin (ALB), high-sensitivity C-reactive protein (hs-CRP), brain natriuretic peptide (BNP), and troponin in patients with coronary heart disease (CHD) failure (HF). In total, 246 CHD-caused HF were selected randomly divided into Group A B. fully automatic biochemical analyzer was used to measure levels ALB, hs-CRP, BNP, both groups patients, expression LVDD LVEF detected by color ultrasonography. Patients B...
Currently, the optimal lymphodepletion intensity for peripheral blood mononuclear cell-derived neoantigen-specific CD8 + T cell (Neo-T) therapy has yet to be determined. We report a single-arm, open-label and non-randomized phase 1 study (NCT02959905) of Neo-T with at various dose in patients locally advanced or metastatic solid tumors that are refractory standard therapies. The primary end point is safety secondary points disease control rate (DCR), progression-free survival (PFS), overall...
Abstract Background Neuroendocrine neoplasm (NEN) of the gallbladder is rare. It usually asymptomatic and occurs in older adults. Its clinicopathological characteristics remain controversial, diagnosis treatment strategies are based on models adenocarcinoma. The present study aimed to investigate clinical prognosis NEN. Methods data patients with NEN admitted Peking Union Medical College Hospital was reviewed, a database established for retrospective analysis. Clinicopathological features...
Background: 'Obesity paradox' was not consistently observed in Asians with coronary artery disease (CAD).Aim: The study investigated the association between body composition and outcomes Chinese patients CAD.Design: Cohort study.Method: A total of 3280 angiographically validated CAD were consecutively included.Body fat (BF) percentage lean mass index (LMI) evaluated using Clı ´nica Universidad de Navarra-Body Adiposity Estimator.The rate mortality from any cause compared across groups...
Circular RNAs (circRNAs) are a class of endogenous non-coding (ncRNAs) with structure covalently closed continuous loops, which can regulate gene expression by acting as microRNA sponge or through other mechanisms. Recent studies have identified that the candidate circRNAs dysregulated in various tumors and hence considered promising diagnostic therapeutic targets across cancer types. However, function lung adenocarcinoma (LUAD) remains unclear. In this article, we investigated LUAD via...