A5069879064- Health disparities and outcomes
- Urban, Neighborhood, and Segregation Studies
- Homelessness and Social Issues
- Gastric Cancer Management and Outcomes
- Intergenerational Family Dynamics and Caregiving
- Cancer, Lipids, and Metabolism
- Colorectal Cancer Surgical Treatments
- Employment and Welfare Studies
- Cancer Research and Treatments
- Inflammatory mediators and NSAID effects
- Food Security and Health in Diverse Populations
- Colorectal Cancer Treatments and Studies
- Cancer Mechanisms and Therapy
- Congenital Anomalies and Fetal Surgery
- CAR-T cell therapy research
- Migration, Health and Trauma
- Helicobacter pylori-related gastroenterology studies
- Lymphoma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Obesity, Physical Activity, Diet
- Pediatric health and respiratory diseases
- Multiple Myeloma Research and Treatments
- Colorectal and Anal Carcinomas
- Medical Imaging and Pathology Studies
- Pancreatic and Hepatic Oncology Research
Fujian Medical University
2013-2025
Union Hospital
2013-2025
The University of Texas at San Antonio
2018-2025
China Medical University
2008-2025
Shanghai Changning Maternity and Infant Health Hospital
2024
East China Normal University
2024
Chongqing Medical University
2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Shenzhen Luohu People's Hospital
2024
Shenzhen University
2024
Neoantigens are ideal targets for dendritic cell (DC) vaccines. So far, only a few neoantigen-based DC vaccines have been investigated in clinical trials. Here, we reported case of patient with metastatic gastric cancer who received personalized neoantigen-loaded monocyte-derived (Neo-MoDC) followed by combination therapy the Neo-MoDC and immune checkpoint inhibitor (ICI). The developed T responses against neoantigens after receiving vaccine alone. following triggered stronger response...
This study uses data from the Panel Study of Income Dynamics, in conjunction with neighborhood-level U.S. decennial census and American Community Survey, to examine trajectory individuals’ neighborhood characteristics initial household formation into mid-to-late adulthood. Multilevel growth curve models reveal both different starting points life course trajectories for blacks whites economic status racial composition. Among respondents who first established an independent during 1970s,...
Abstract Since the expansion of social insurance to migrants and abolition unequal regulations controls related rural–urban in recent years, increasing attention has been paid determinants migrants' settlement intentions. Using 2016 National Floating Population Dynamics Monitoring Survey (NFPDMS), this study examines associations between urban welfare participation their intentions, including long‐term intention transfer one's hukou status. Results from logistic regression show that schemes...
Background Statins, which are medications that lower lipid levels, extensively used to decrease cardiovascular disease risk. Recently, the use of statins in cancer prevention has attracted considerable interest. However, it is still unclear whether a causal effect on bladder cancer. Methods The two-sample Mendelian Randomization (MR) was performed infer relationship between statin therapy (atorvastatin, simvastatin, and rosuvastatin) Single-nucleotide polymorphisms (SNP)-based genome-wide...
Resveratrol (3,5,4'-trihydroxystilbene), a natural product derived from grapes, has been reported to exert plethora of biological functions. Recent studies suggest that resveratrol could act as cardioprotective agent by controlling the oxidation low density lipoproteins, well proliferation endothelial cells. Since migration and smooth muscle cells (SMCs) in intima susceptible vessels is also widely accepted requisite for atherogenesis, we investigated effects on cell cycle control cultured...
Late-life depression (LLD) has negative impacts on somatic, emotional and cognitive domains of the lives patients. Elucidating abnormality in brain networks LLD patients could help to strengthen understanding pathophysiology, however, studies exploring spontaneous activity during resting state remain limited. This study aimed at identifying voxel-level whole-brain functional connectivity changes patients.Fifty with late-life 33 healthy controls were recruited. All participants underwent a...
Early-stage breast cancer (BC) presents a certain risk of axillary lymph node (ALN) metastasis (ALNM), leading to different individualized treatment. Preoperative non-invasive prediction determine ALN status is great significance for avoiding ineffective surgery. Tumor total hemoglobin concentration (TTHC), strain ratio (SR), and Ki-67 expression are associated with ALNM in BC, but few studies have focused on T1 BC. This study aimed explore the usefulness these factors individually...
Robot-assisted surgery has increasingly gained recognition in the treatment of rectal cancer. This study aimed to assess incidence surgical site infection (SSI) that underwent robot-assisted radical cancer and evaluate their influence on patient outcomes. A retrospective analysis was conducted 360 patients who between 2017 2024 at Fujian Medical University Union Hospital Longyan First Affiliated University. The were categorized into non-surgical groups based presence infection. Baseline...
ABSTRACT Objective This study investigates the longitudinal association between caring for parents/in‐laws and cognitive functioning among adult children in China. It also examines how this is influenced by relationship type (own parents vs. in‐laws), caregiving intensity, gender of caregiver. Background While family often seen as stressful negatively impacting caregivers' health, recent evidence suggests that may improve particularly through cognitively stimulating activities can help...
Introduction: Vascular dementia (VaD) is a heterogeneous disease that can vary in clinical presentation and cognitive profile.The profiles of different VaD subtypes depend on the anatomical distribution vascular insults have been documented.Material methods: We reviewed demographic, cognitive, imaging data 402 patients who were clinically diagnosed with between January 2002 June 2012 at First Affiliated Hospital Gan Nan Medical College Ganzhou, China.Results: Based magnetic resonance (MRI)...
Currently, the optimal lymphodepletion intensity for peripheral blood mononuclear cell-derived neoantigen-specific CD8 + T cell (Neo-T) therapy has yet to be determined. We report a single-arm, open-label and non-randomized phase 1 study (NCT02959905) of Neo-T with at various dose in patients locally advanced or metastatic solid tumors that are refractory standard therapies. The primary end point is safety secondary points disease control rate (DCR), progression-free survival (PFS), overall...
Food insecurity is negatively related to child development and health. In this study, we use Early Childhood Longitudinal Study–Birth Cohort data assess the cognitive health consequences of household food for children immigrants compared with native-born parents. Results suggest that from insecure households fare worse than their native peers in but not skills after maternal demographic characteristics are taken into account. The remaining disparity between immigrant nonimmigrant explained...
PE vte Objective: We aimed to determine which combination of physical examination (PE), mammography (MAM), and ultrasonography (US) would optimize breast cancer detection in China. Methods: conducted a trial screening with pe, mam, us among Chinese women 25 years age older. All initial screenings using the three modalities were completed within 30 days each other, subjects followed approximately 1 year later. The performances methods used alone, parallel, or series compared. Data analyzed...
We examined the whole genome expression profile in advanced colorectal cancer (ACC) patients who had received FOLFOX4 chemotherapy to establish a genetic biomarker model predicting sensitivity.Eligible ACC were divided into two groups, based on postchemotherapy evaluation results: specifically, sensitive group (experimental group) and resistant (control group). The profiles of tissues using DNA microarray analysis, differential gene was identified significance analysis microarray. probe...