A5103009147- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Screening and Detection
- Metastasis and carcinoma case studies
- Radiomics and Machine Learning in Medical Imaging
- Anorectal Disease Treatments and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal Tumor Research and Treatment
- Surgical site infection prevention
- Nanoplatforms for cancer theranostics
- Diagnosis and treatment of tuberculosis
- Pelvic floor disorders treatments
- Congenital gastrointestinal and neural anomalies
- Gastrointestinal motility and disorders
- Inflammatory Biomarkers in Disease Prognosis
- Epigenetics and DNA Methylation
- Esophageal Cancer Research and Treatment
- Bladder and Urothelial Cancer Treatments
- Diverticular Disease and Complications
- Viral-associated cancers and disorders
- Cancer Mechanisms and Therapy
- Cancer, Lipids, and Metabolism
Fujian Medical University
2015-2025
First Affiliated Hospital of Fujian Medical University
2015-2025
Longyan University
2019-2024
Fujian University of Traditional Chinese Medicine
2024
Shanghai Jiao Tong University
2024
Kunming Medical University
2022
State Key Laboratory of Oncology in South China
2019
Chinese People's Liberation Army
2019
Sun Yat-sen University
2019
Sun Yat-sen University Cancer Center
2019
The efficacy of laparoscopic vs open surgery for patients with low rectal cancer has not been established.
To compare neoadjuvant chemotherapy (nCT) with CAPOX alone versus chemoradiotherapy (nCRT) capecitabine in locally advanced rectal cancer (LARC) uninvolved mesorectal fascia (MRF).nCRT is associated higher surgical complications, worse long-term functional outcomes, and questionable survival benefits. Comparatively, nCT seems a promising alternative treatment lower-risk LARC patients MRF.Patients between June 2014 October 2020 within 12 cm from the anal verge MRF were randomly assigned to...
The use of percutaneous transcatheter hepatic arterial chemotherapy and embolization in the treatment primary liver cancer has become increasingly popular recent years. authors employed this method, using a combination cisplatin, mitomycin C, 5-fluorouracil, ethiodized oil (Lipiodol) or absorbable gelatin sponge 30 patients with huge cancers (diameter range, 5.6-12.0 cm) as preliminary before resection. Significant tumor regression occurred after treatment, converting these tumors into...
The long-term survival of patients with laparoscopic total gastrectomy combined spleen-preserving splenic hilar lymphadenectomy (LSTG) for advanced upper-third gastric cancer (AUTGC) and the association lymph node (LN-10) metastasis remain controversial.To evaluate outcomes LSTG value index LN-10 AUTGC.The Chinese Laparoscopic Gastrointestinal Surgery Study 4 (CLASS-04) was a prospective, multicenter, single-arm trial that involved 19 centers in China. A 251 eligible clinical stage T2, T3,...
Background: The efficacy of laparoscopic completion total gastrectomy (LCTG) for remnant gastric cancer (RGC) remains controversial. Methods: primary outcome was postoperative morbidity within 30 days after surgery. Secondary outcomes included 3-year disease-free survival (DFS), overall (OS), and recurrence. Inverse probability treatment weighted (IPTW) used to balance the baseline between LCTG OCTG. Results: Final analysis 46 patients with RGC who underwent at FJMUUH June 2016 2020....
Objective: To investigate the prognostic impact of perineural invasion in patients with stageⅢ colon cancer and to clarify its guidance value for duration postoperative adjuvant chemotherapy. Methods: This study employed a retrospective cohort method. It analyzed 426 who underwent radical surgery at Sun Yat-sen University Cancer Center Longyan First Affiliated Hospital Fujian Medical University, between April 2008 June 2020. Inclusion criteria: received least 3 months CapeOX therapy...
Robot-assisted surgery has increasingly gained recognition in the treatment of rectal cancer. This study aimed to assess incidence surgical site infection (SSI) that underwent robot-assisted radical cancer and evaluate their influence on patient outcomes. A retrospective analysis was conducted 360 patients who between 2017 2024 at Fujian Medical University Union Hospital Longyan First Affiliated University. The were categorized into non-surgical groups based presence infection. Baseline...
Abstract The present study was designed to evaluate the dynamic survival and recurrence of remnant gastric cancer (RGC) after radical resection provide a reference for development personalized follow‐up strategies. A total 298 patients were analyzed their 3‐year conditional overall (COS3), disease‐specific (CDSS3), corresponding pattern changes, associated risk factors. 5‐year (OS) (DSS) entire cohort 41.2% 45.8%, respectively. COS3 CDDS3 RGC who survived 5 years 84.0% 89.8%, in with...
Conditional survival (CS) takes into consideration the duration of post-surgery and can provide valuable additional insights. The aim this study was to investigate risk factors associated with reduced one-year postoperative conditional in patients diagnosed stage III T3-T4 colon cancer real-time prognosis prediction. Furthermore, we develop pertinent nomograms predictive models.
The log odds of positive lymph nodes (LODDS) was considered a superior staging system to N stage in colon cancer, yet its value determining the optimal duration adjuvant chemotherapy for III cancer patients has not been evaluated. This study aims assess prognostic model that combines LODDS with clinicopathological information and stratify these using model, identifying individuals who could benefit from varying durations chemotherapy. A total 663 consecutive diagnosed underwent tumor...
Abstract Microwave surgery was employed for the treatment of 50 patients with hepatocellular carcinoma (HCC) and liver cirrhosis, including hepatectomy in 46 situ coagulation tumor 4 patients. In study, 2,450 MHz microwaves were generated transmitted to a monopolar needle electrode. For hepatectomy, electrode inserted into parenchyma coagulate tissue this repeated at 1 cm intervals along line where incision is anticipated. unresectable HCC, directly HCC cancer situ. The average amounts blood...
MicroRNAs can regulate the transcription of protein-coding genes associated with development and progression cancer. In this study, we explored potential diagnostic function exosome miR-3184-5p in gastric This was isolated from blood samples 150 patients cancer 60 healthy participants. The mean particle size concentration serum were 104.6 nm (93.97-115.84) 6.21e+009 particles/ml (5.15e+009-7.12e+009), respectively. expression substantially downregulated compared that cell line HGC-27...
Purpose The aim to assess treatment failure in patients with stage III colon cancer who underwent radical surgery and was analyzed using the nomogram. Methods Clinical factors survival outcomes for registered SEER database from 2018 2019 were analyzed, split into training testing cohorts (7:3 ratio). A total of 360 First Affiliated Hospital Longyan served as an external validation cohort. Independent predictors identified logistic regression analyses. nomograms evaluated by concordance index...
Abstract Purpose The optimal number of lymph nodes to be resected in patients with rectal cancer who undergo radical surgery after neoadjuvant therapy remains controversial. This study evaluated the prognostic variances between elderly and non-elderly determined ideal removed these patients. Methods Surveillance, Epidemiology, End Results (SEER) datasets were used gather information on 7894 diagnosed stage T3-4/N+ underwent from 2010 2019. Of patients, 2787 5107 non-elderly. A total 152...
Background Endoscopic obstruction (eOB) is associated with a poor prognosis in colorectal cancer (CRC). Our study aimed to investigate the association between tumor location and eOB, as well prognostic differences among non-endoscopic (N-eOB), eOB size ≤ 5 cm, > cm non-elderly patients. Methods We retrospectively reviewed clinicopathological variables of 230 patients CRC who underwent curative surgery. The multivariable logistic regression model was used identify risk factors for eOB....
Background . Remnant gastric cancer (RGC) is a rare malignant tumor with poor prognosis. There no universally accepted prognostic model for RGC. Methods We analyzed data 253 RGC patients who underwent radical gastrectomy from 6 centers. The prognosis prediction performances of the AJCC7th and AJCC8th TNM staging systems TRM system were evaluated. Web-based models based on independent factors developed to predict survival patients. External validation was performed using cohort 49 Chinese...