A5101967570- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Gastric Cancer Management and Outcomes
- Telomeres, Telomerase, and Senescence
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- RNA and protein synthesis mechanisms
- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- Child Nutrition and Feeding Issues
- Phytochemicals and Antioxidant Activities
- Genetics and Plant Breeding
- Genetic Associations and Epidemiology
- Plant Gene Expression Analysis
- Helicobacter pylori-related gastroenterology studies
- Ionic liquids properties and applications
- Gait Recognition and Analysis
- Bioinformatics and Genomic Networks
- Cystic Fibrosis Research Advances
- Machine Learning in Bioinformatics
- Mesenchymal stem cell research
- Evolution and Genetic Dynamics
- Genomics and Rare Diseases
- Tissue Engineering and Regenerative Medicine
- Plant biochemistry and biosynthesis
Guangxi Buffalo Research Institute
2025
Chinese Academy of Agricultural Sciences
2023-2025
Guangxi Medical University
2024
Hangzhou Hospital of Traditional Chinese Medicine
2024
Yangzhou University
2024
Beijing Jiaotong University
2023
Hubei University of Medicine
2023
Southwest University
2023
Institute of Crop Sciences
2023
Union Hospital
2016-2021
ObjectivesTo determine safety and efficacy of the 5HT1A serotonin partial agonist buspirone on core autism associated features in children with spectrum disorder (ASD).Study designChildren 2-6 years age ASD (N = 166) were randomized to receive placebo or 2.5 5.0 mg twice daily. The primary objective was evaluate effects 24 weeks Autism Diagnostic Observation Schedule (ADOS) Composite Total Score. Secondary objectives included evaluating social competence, repetitive behaviors, language,...
Clear cell renal carcinoma (ccRCC) is the most common and aggressive subtype of kidney cancer. Loss von Hippel-Lindau (VHL) consequent activation hypoxia-inducible factor-α (HIFα, especially HIF2α) plays an essential role in ccRCC initiation progression. The approved HIF2α inhibitor belzutifan faces challenge resistance, presenting opportunity co-targeting another vulnerability. This study elucidates synthetic essentiality TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)...
Single nucleotide polymorphisms in the human genome have become an increasingly popular topic that their analyses promise to be a key step toward personalized medicine. We investigate two related questions, how much haplotype information contributes linkage disequilibrium (LD) mapping and whether silico construction preceding LD analysis can help. For disease gene mapping, using both simulated real data sets on cystic fibrosis Alzheimer disease, we reached following conclusions: (1) for...
In this paper some parametric methods are introduced to characterize the self-similarity of DNA sequences. Compared with Fourier analysis, these perform statistically more stably and yield reliable results. Using methods, eight whole genomes bacteria provided by NCBI analyzed. Long-range correlation properties in nucleotide density distribution along sequences explored. Estimation results show that long-range structure prevails through entire molecule DNA. Higher order statistics coarse...
The aim of this work was to explore the predictive value changes in level carbohydrate antigen 19-9 (CA19-9) after neoadjuvant chemoradiotherapy (nCRT) and surgery patients with locally advanced rectal cancer (LARC).Patients LARC who underwent nCRT radical (between 2011 2016) were divided into three groups according pre-nCRT post-nCRT CA19-9 levels as follows: normal (normal group), elevated (normalized group) (nonnormalized group). pathological response criteria included ypCR downstaging...
Flowering time (FT) is a key maize domestication trait, variation in which allows to grow wide range of latitudes. Although previous studies have investigated the genetic control FT-related traits per se, few FT hybrid performance been published. We characterized genomic architecture associated with for panel by testcrossing Chang 7-2 328 Ye478 × Qi319 recombinant inbred lines (RILs). identified 11 quantitative trait loci (QTL) traits, including major QTL qFH10 that controls and heterosis...
Abstract Ionic liquids (ILs) are thought to have negative effects on human health. Researchers explored the of ILs zebrafish development during early stages, but intergenerational toxicity has rarely been reported. Herein, parental were exposed different concentrations (0, 12.5, 25, and 50 mg/L) [C n mim]NO 3 ( = 2, 4, 6) for 1 week. Subsequently, F1 offspring cultured in clean water 96 h. exposure inhibited spermatogenesis oogenesis F0 adults, even causing obvious lacunae testis atretic...
Metabolic engineering of anthocyanin synthesis is an active research area for pigment breeding and remains a hotspot involving AtPAP1 ZmLc transcription factors. Caladium bicolor desirable metabolic receptor, with its abundant leaf color stable genetic transformation system.We transformed C. successfully obtained transgenic plants. We then used combination metabolome, transcriptome, WGCNA PPI co-expression analyses to identify differentially expressed components transcripts between wild-type...
Atrophic gastritis is of high risk progressing to gastric cancer. Screening early cancer and predicting the atrophic developing into could improve prognosis This study evaluated significance miR-1260b in progression aiming explore a reliable biomarker. The enrolled 78 patients 77 patients. expression was detected serum tissue samples by PCR. assessed correlated with levels. potential distinguishing ROC. In vitro, cells were infected Helicobacter pylori, regulatory effect on cell growth...
The simultaneous occurrence of head and neck squamous carcinoma in two anatomical sites is rare, posing challenges treatment selection. This paper presents a clinical case concurrent hypopharyngeal nasopharyngeal carcinoma, successfully treated with combination chemoradiotherapy an immune checkpoint inhibitor. patient achieved complete remission progression-free survival nearly 3 years, preserved organ function minimal toxic side effects, leading to good quality life. highlights the...
In order to solve the problem of lack temporal and multi-scale information in gait recognition tasks based on energy images. A method two-branch network is proposed. convolutional branch, attention mechanism residual connection are combined design a feature extraction module obtain effective features. simple image constructed input into long short-term memory extract More accurate classification can be achieved by combining two types Experimental results open dataset CASIA-B show that...