- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Gastrointestinal motility and disorders
- Liver Disease and Transplantation
- Infant Health and Development
- Liver Diseases and Immunity
- COVID-19 Clinical Research Studies
- HIV, Drug Use, Sexual Risk
- SARS-CoV-2 and COVID-19 Research
- Homelessness and Social Issues
- Congenital gastrointestinal and neural anomalies
- Diet and metabolism studies
- Vaccine Coverage and Hesitancy
- Long-Term Effects of COVID-19
- Systemic Lupus Erythematosus Research
- Viral Infections and Outbreaks Research
- Diet, Metabolism, and Disease
- COVID-19 epidemiological studies
- Pancreatitis Pathology and Treatment
- Criminal Justice and Corrections Analysis
- Hepatitis Viruses Studies and Epidemiology
- Music Therapy and Health
- 3D Shape Modeling and Analysis
- Tryptophan and brain disorders
Link Campus University
2024-2025
University of Siena
2024
Azienda Ospedaliero-Universitaria Careggi
2011-2024
Agenzia Regionale di Sanità della Toscana
2014-2024
University of Florence
2014-2023
Regione Toscana
2022
Azienda USL di Bologna
2022
University of Bologna
2022
University of Bari Aldo Moro
2022
University of Pisa
2003-2015
Liver tissue alterations other than fibrosis may have an impact on liver stiffness measurement. In this study we evaluated 18 patients without a previous clinical history of disease, consecutively admitted for acute viral hepatitis. each patient, aminotransferase determination and measurement were performed the same day, at 3 different points: (1) peak increase in aminotransferase; (2) 50% or less peak; (3) levels ≤2× upper limit normal. all patients, degree time aminotransferases exceeded...
Hepatitis C virus (HCV)‐associated mixed cryoglobulinemia (MC) vasculitis commonly regresses upon eradication, but conventional therapy with pegylated interferon and ribavirin yields approximately 40% sustained virologic responses (SVR). We prospectively evaluated the efficacy safety of sofosbuvir‐based direct‐acting antiviral therapy, individually tailored according to latest guidelines, in a cohort 44 consecutive patients HCV‐associated MC. In two MC had evolved into an indolent lymphoma...
Background: Transient elastography (TE) has received increasing attention as a means to evaluate disease progression in patients with chronic liver disease. Aim: To assess the value of TE for predicting stage fibrosis. Methods: Liver biopsy and were performed 150 consecutive hepatitis C-related (92 men 58 women, age 50.6 (SD 12.5) years on same day. Necro-inflammatory activity degree steatosis at also evaluated. Results: The areas under curve prediction significant fibrosis (⩾F2), advanced...
Abstract Transient elastography (TE) is increasingly employed in clinical practice for the noninvasive detection of tissue fibrosis patients with chronic liver disease (CLD), and particularly hepatitis C virus (HCV)-related hepatitis. The present study was designed to provide a definitive characterization “confounding” increase stiffness (LS) following standardized meal consecutive population 125 HCV infection at different stages fibrotic evolution. LS values were obtained after overnight...
Limited data are available about the efficacy of antiviral treatment in hepatitis C virus (HCV)–associated mixed cryoglobulinemia (MC), especially concerning long‐term effects HCV eradication. The aim this study was to evaluate influence MC on virological response and viral eradication MC. We prospectively enrolled 424 + patients belonging following groups: syndrome (MCS)‐HCV (121 with symptomatic MC), MC‐HCV (132 asymptomatic (158 without MC). Pegylated interferon plus ribavirin...
Abstract Aims The aims of this study were to better define the relationship between irritable bowel syndrome (IBS) and psychiatric disorders examine efficacy paroxetine in treatment IBS patients. Methods One hundred fifty subjects with diagnosis (Roma III criteria) relative sub‐classification (constipated, diarrhea, mixed) assessed for psychopathological features gastrointestinal symptoms using Symptom Severity Score consecutively enrolled . Fifty patients assumed 16 weeks longitudinally...
One of the main objectives World Health Organization is eradication viral hepatitis by 2030 identifying subjects before disease progression. In 2019, only 21% 58 million people chronically infected with C virus (HCV) had been diagnosed, while overall 13% treated. The key recommendation international screening programs to reach at major risk and general population. National plans, including that in Italy, have dedicated budget lines support efforts achieve objective elimination. Italian...