Brenda Leticia Escobedo-Guajardo

ORCID: 0000-0002-9184-0296
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Influenza Virus Research Studies
  • Amoebic Infections and Treatments
  • SARS-CoV-2 and COVID-19 Research
  • Tuberculosis Research and Epidemiology
  • Long-Term Effects of COVID-19
  • Pancreatitis Pathology and Treatment
  • Pediatric Hepatobiliary Diseases and Treatments
  • Animal Disease Management and Epidemiology
  • Sepsis Diagnosis and Treatment
  • Viral gastroenteritis research and epidemiology
  • Reproductive tract infections research
  • Veterinary Medicine and Surgery
  • Nutritional Studies and Diet
  • Pneumonia and Respiratory Infections
  • Parasitic infections in humans and animals
  • RNA and protein synthesis mechanisms
  • Vitamin D Research Studies
  • Parasitic Infections and Diagnostics
  • Cancer therapeutics and mechanisms
  • Parasites and Host Interactions
  • Frailty in Older Adults
  • Respiratory viral infections research
  • Computational Drug Discovery Methods
  • Vaccine Coverage and Hesitancy

Mexican Social Security Institute
2007-2025

Universidad Autónoma de Nuevo León
2010-2013

People with comorbidities and the male sex are at a higher risk of developing severe COVID-19. In present study, we aim to investigate associated factors for infection, severity, death due COVID-19 in population from Nuevo León, México. Epidemiological data were collected 65 hospitals December 2020 May 2022. A total 75,232 cases compiled which 25,722 positive SARS-CoV-2. Male sex, older age, diabetes, obesity, hypertension infection. addition above-mentioned factors, renal disease,...

10.3390/jcm12072676 article EN Journal of Clinical Medicine 2023-04-03

Abstract The disease caused by the influenza virus is a global public health problem due to its high rates of morbidity and mortality. Thus, analysis information generated epidemiological surveillance systems has vital importance for decision making. A retrospective was performed using data four molecular diagnostic laboratories Mexican Social Security Institute between 2010 2016. Demographics, positivity, seasonality, treatment choices vaccination status analyses were vaccine according...

10.1017/s0950268819000694 article EN cc-by Epidemiology and Infection 2019-01-01

Background/Objectives: Metabolic syndrome (MetS) is a predisposing factor for severe COVID-19. The effectiveness of COVID-19 vaccines in patients with MetS has been poorly investigated. aim this study was to evaluate the vaccination before (BO) and after Omicron (AO) SARS-CoV-2 variant MetS. Methods: This retrospective observational carried out total 3194 PCR or rapid antigen test. main outcomes were vaccine against infection, hospitalization death resulting from Results: BO, only two doses...

10.3390/vaccines13030244 article EN cc-by Vaccines 2025-02-27

Drug-resistant tuberculosis is a pressing global health issue that requires the development of new drugs or identification therapeutic targets. The ESX-3 secretion system essential for Mycobacterium growth and plays role in iron/zinc homeostasis virulence. aim this study was to evaluate quaternary interface EccD3, component system, association an eccD3 mutant with drug resistance. molecular structures EccD3 protein other proteins M. were predicted based homology Mycolicibacterium smegmatis...

10.1371/journal.pcbi.1012936 article EN cc-by PLoS Computational Biology 2025-04-17

La influenza es una enfermedad infecciosa que se caracteriza por cuadros de fiebre alta y malestar general. Desde la pandemia originada en México 2009 el virus A(H1N1)pdm09, este ha estado circulando hasta actualidad, afectando a miles personas todo país cada temporada. Durante COVID-19, debido al aumento las medidas prevención, los casos reportados temporadas anteriores 2023 fueron menores, sin embargo, enero 2024, había tenido un nivel internacional, siendo subtipo predominante A(H1N1)....

10.29105/cienciauanl28.130-3 article ES Revista Ciencia UANL 2025-03-03

Abstract Background One of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age also associated with comorbidities, which are severe infection. Among tools that have been evaluated to predict intensive care unit (ICU) admission ABC-GOALScl. Aim In present study we validated utility ABC-GOALScl in-hospital in subjects over 60 years who were positive SARS-CoV-2 virus at moment purpose optimizing sanitary resources offering...

10.1186/s12877-023-03864-8 article EN cc-by BMC Geriatrics 2023-03-10

Neither phospholipase A1 (PLA A1) nor A2 A2), their respective genes, have been identified in Giardia lamblia, even though they are essential for lipid metabolism this parasite. A method to identify, isolate, and characterize these enzymes is needed. The activities of PLA were analyzed a total extract (TE) vesicular (P30) soluble (S30) subcellular fractions G. lamblia trophozoites; the effects several chemical physicochemical factors on investigated. assays performed using substrate labeled...

10.1645/ge-1038r3.1 article EN Journal of Parasitology 2007-10-01

The end of the coronavirus disease 2019 (COVID-19) pandemic has been declared by World Health Organization on May 5, 2023. Several vaccines were developed, and new data is being published about their effectiveness. However, clinical trials for performed before Omicron variant appeared there are population groups where vaccine effectiveness still needs to be tested. overarching goal present study was analyze effects COVID-19 vaccination after in patients considering comorbidities a from Nuevo...

10.3389/fpubh.2024.1402527 article EN cc-by Frontiers in Public Health 2024-06-12

Abstract Sexually transmitted diseases are a major cause of acute disease worldwide, and trichomoniasis is the most common curable disease, generating more than 170 million cases annually worldwide. Trichomonas vaginalis causal agent has ability to destroy in vitro cell monolayers vaginal mucosa, where phospholipases A2 (PLA2) have been reported as potential virulence factors. These enzymes partially characterized from subcellular fraction S30 pathogenic T. strains. The main objective this...

10.2478/s11686-013-0166-2 article EN cc-by-nc-nd Acta Parasitologica 2013-01-01

Aging is commonly accompanied by increased cardiovascular risk and diet plays a crucial role in health condition. The aim of this study was to determine factors as predictors nutritional Mexican older adults. A cross-sectional on patients aged ≥60 years with affiliated medical unit Northeast Mexico performed from July December 2021. evaluations were using the Mini Nutritional Assessment (MNA) questionnaire. After multivariate analysis, identified independent malnutrition hypertriglyceridemia...

10.3390/nu16162662 article EN Nutrients 2024-08-12
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