- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Neutropenia and Cancer Infections
- Cutaneous Melanoma Detection and Management
- Genetics, Bioinformatics, and Biomedical Research
- Fungal Infections and Studies
- Gene expression and cancer classification
- Trace Elements in Health
- AI in cancer detection
- Pharmacological Effects of Medicinal Plants
- Blood disorders and treatments
- Cancer Genomics and Diagnostics
- Oral health in cancer treatment
- Head and Neck Cancer Studies
- Childhood Cancer Survivors' Quality of Life
- Advanced Radiotherapy Techniques
- Cancer Treatment and Pharmacology
- Radiomics and Machine Learning in Medical Imaging
- Bone Metabolism and Diseases
- Breast Implant and Reconstruction
Hiroshima University
2024-2025
Masaryk University
2024
Hiroshima University Hospital
2022-2024
Axillary staging is commonly performed in patients with clinically node-positive (cN+) breast cancer undergoing neoadjuvant chemotherapy (NACT), regardless of pathological complete response (pCR). Recent evidence has suggested that ypT0 correlates ypN0 and favorable prognosis, potentially supporting the omission axillary such cases. This study aimed to evaluate as a predictive factor for ypN status its prognostic significance cN+ treated NACT. retrospective included 302 NACT at Hiroshima...
Radiofrequency ablation (RFA) is considered a promising alternative to surgical excision for patients with small, unifocal early-stage breast cancer. A significant concern the application of RFA in diagnosed ductal carcinoma situ (DCIS) via needle biopsy underdiagnosis invasive The extent this DCIS eligible has not been clearly defined. This retrospective study assessed lesions as and at our institution from April 2009 March 2024. eligibility criteria included lesion size ≤ 1.5 cm,...
e13033 Background: Based on the companion diagnostic function of Comprehensive Cancer Genome Profiling (CGP) test in Japan, pembrolizumab is standard treatment for patients with Tumor Mutational Burden (TMB)-high (H) solid tumors. In this report, we attempted to extract predictive factors TMB-H from CGP results. Methods: We carried out a retrospective cohort study 42 malignant breast tumors (excluding circulating tumor DNA blood) who underwent testing between June 1, 2019, and November 30,...
The tumor-infiltrating lymphocytes-ultrasonography score is a calculation system for predicting lymphocyte-predominant breast cancers in surgical specimens. A nomogram based on the was developed to predict pathological complete response cancer treated with neoadjuvant chemotherapy.
The failure of intracellular zinc accumulation is a key process in prostate carcinogenesis. Although cancer cells can accumulate after long-term exposure, chronic oversupply may accelerate carcinogenesis or chemoresistance. Because progression associated with energetically demanding cytoskeletal rearrangements, we investigated the effect presence on biophysical parameters, ATP production, and EMT characteristics two cell lines (PC-3, 22Rv1). Prolonged exposure to increased spare respiratory...
<title>Abstract</title> Background Radiofrequency ablation (RFA) is considered a promising alternative to surgical excision for patients with small, unifocal early-stage breast cancer. A significant concern the application of RFA in diagnosed ductal carcinoma situ (DCIS) via needle biopsy underdiagnosis invasive The extent this DCIS eligible has not been clearly defined. Methods This retrospective study assessed lesions as and at our institution from April 2009 March 2024. eligibility...
Docetaxel and cyclophosphamide (TC) combination therapy is widely used as adjuvant chemotherapy for early-stage breast cancer associated with a high incidence of febrile neutropenia (FN). Granulocyte colony-stimulating factor (G-CSF) recommended in the primary prevention This study aimed to evaluate FN-suppressing effect G-CSF patients receiving TC.We performed 272 treatment cycles after FN onset 106 TC. We retrospectively evaluated secondary prophylaxis. The frequency was calculated based...