A5101443432- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Tracheal and airway disorders
- Ferroptosis and cancer prognosis
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Inflammatory Biomarkers in Disease Prognosis
- Neurosurgical Procedures and Complications
- Cardiac Ischemia and Reperfusion
- MicroRNA in disease regulation
- Congenital Diaphragmatic Hernia Studies
- Healthcare and Venom Research
- Head and Neck Anomalies
- Acupuncture Treatment Research Studies
- Tumors and Oncological Cases
- Anesthesia and Neurotoxicity Research
- Heart Rate Variability and Autonomic Control
- Advanced Technologies in Various Fields
- Dysphagia Assessment and Management
- Foreign Body Medical Cases
- Traditional Chinese Medicine Studies
First Hospital of Jilin University
2016-2025
Jilin University
2016-2025
Zhengzhou Railway Vocational & Technical College
2023
Creative Commons
2019
UNSW Sydney
2019
The George Institute for Global Health
2019
Qilu Hospital of Shandong University
2013-2019
Beijing Jishuitan Hospital
2012
Peking University
2012
University of Maryland, Baltimore
2011
Background The changes in the platelet-to-lymphocyte ratio (PLR) before and after recombinant tissue plasminogen activator (rtPA) treatment time point at which PLR is a potentially valuable prognostic predictor patients wit ischemic stroke remain largely unknown. Therefore, purpose of this study was to explore characteristics evaluate their effects on clinical outcomes 24 h rtPA treatment. Methods This included 741 consecutive with acute who underwent intravenous thrombolysis rtPA. We...
BACKGROUND: Approximately half of the patients with acute ischemic stroke who receive intravenous thrombolysis (IVT) do not achieve an excellent outcome. Remote conditioning (RIC) as a promising neuroprotective treatment may improve clinical outcomes in this population. This study aimed to assess efficacy and safety RIC IVT. METHODS: multicenter, participant-blinded, blinded end point, randomized controlled trial included 558 underwent IVT 18 hospitals from August 2021 May 2023. After IVT,...
BACKGROUND Patients who undergo cardiac surgery often face postoperative pain and potential cognitive issues. Multimodal analgesia may address these problems. We hypothesized that multimodal can reduce opioid use improve recovery. AIM To investigate the effects of on consumption recovery in patients underwent surgery. METHODS A prospective, randomized controlled trial at General Hospital from January 2020 to April 2023 recruited a total 150 adult elective The were randomly divided into two...
Hyperalgesia and allodynia are commonly observed in patients with diabetic neuropathy. The treatment management of painful peripheral neuropathy is important these patients. purpose this study was to examine the role exercise modulating neuropathic pain induced by diabetes. Diabetes rats an intraperitoneal injection streptozotocin (STZ). Control received saline injections. Groups included control without (NT-control, n = 12), (EX-control, 16), STZ (NT-STZ, 18), (EX-STZ, 22). Rats EX groups...
Background: The association between patent foramen ovale (PFO) and migraine has been reported. However, whether transcatheter PFO closure is effective in alleviating remains controversial. objective of this study was to investigate the efficacy a 5-year follow-up. Methods: Migraineurs with from 2013 2015 were included divided into group non-PFO according their therapy. Contrast-enhanced transcranial Doppler (c-TCD) performed evaluate degree right-to-left shunt (RLS), headache impact test...
Background and purpose The burden of cervical arterial atherosclerosis, which is an important risk factor stroke, huge in China. visceral adiposity index (VAI) a convenient that related to series metabolic abnormalities variety diseases, including cerebrovascular diseases. This study aimed explore the relationship between VAI atherosclerosis. Methods cross‐sectional used multistage stratified random cluster sampling method acquire representative sample residents aged ≥40 general population...
Background and Purpose: Dynamic cerebral autoregulation (dCA) is probably impaired in the acute even subacute phases after ischemic stroke (AIS); however, relationship between relevant clinical factors dCA AIS has not been investigated. The identification of possible determinants may therefore provide potential therapeutic targets to improve AIS. Methods: This study enrolled 67 consecutive patients diagnosed with within 3 days from symptom onset. Serial measurements were performed 1-3...
Background and purpose: Intravenous thrombolytic therapy significantly improves the outcomes of acute ischemic stroke patients in a time-dependent manner. The aim this study was to investigate whether continuous nursing quality improvement nurses has positive effect on reducing time thrombolysis stroke. Methods: implementation measures includes establishing full-time nurses, pre-notification by emergency medical services (EMS), team notification protocols, rapid triage, publicity education,...
Background and Purpose: Platelet-to-neutrophil ratio (PNR) was suggested to be an independent protective predictor for 90-days outcomes in acute ischemic stroke (AIS) patients previous studies. This study aims investigate the association between PNR of AIS intravenous thrombolysis (IVT) group. Methods: Data on who received from April 2015 March 2019 were collected. We defined value at admission as pre-IVT after IVT within 24 h post-IVT PNR. Clinical outcome indicators included early...
Deep vein thrombosis (DVT) is common among patients with stroke. However, the incidence of DVT in acute ischemic stroke treated thrombolytic therapy and risk factors associated this condition are unknown.This study aimed to investigate after thrombolysis stroke.We retrospectively reviewed medical records all who underwent ultrasonic examination intravenous between April 2017 December 2019 at center First Hospital Jilin University, China. Color duplex ultrasound was used diagnosis within 72 h...
The influence of the anterior and posterior communicating artery (ACoA PCoA) on dynamic cerebral autoregulation (dCA) is largely unknown. In this study, we aimed to test whether substantial differences in collateral anatomy were associated with dCA two common types stenosis according digital subtraction angiography (DSA): either isolated basal and/or bilateral vertebral arteries severe stenosis/occlusion (group 1; group 1A: PCoAs; 1B: without PCoAs), or unilateral internal carotid 2; 2A:...
Background—From 2017, the Stroke Health Manager Training Project was carried out by Chinese Government to strengthen health management and follow-up intervention after ischemic stroke. The aim of this study investigate whether stroke manager, control blood pressure, low-density lipoprotein cholesterol (LDL-C), glucose level, use secondary prevention medications improved three months discharge from our center following Methods—The used a history-controlled approach. Patients who received...
It remains challenging to locate occult lesions in patients with multiple sclerosis (MS). Diffusion tensor imaging (DTI) has been demonstrated have the potential identify changes MS lesions. The present study used 3.0T magnetic resonance DTI investigate characteristics of different stages parameters, fractional anisotropy (FA), mean diffusivity (MD), λ// and λ┴ values were compared at 10 normal controls. results that FA silent subacute are decreased MD increased, as those appearing white...
The aim of this study was to establish a nomogram model for individualized early prediction the 3-month prognosis in patients with acute ischemic stroke (AIS) who were treated intravenous recombinant tissue plasminogen activator (rt-PA) thrombolysis.A total 691 included study; 564 training cohort, while 127 test cohort. main outcome measure unfavorable (modified Rankin Scale 3-6). To construct model, stepwise logistic regression analysis applied select significant predictors outcome....
Some common modified vascular risk factors remain poorly controlled among stroke survivors, and educational programs may help improve these conditions.
Generalized anxiety disorder (GAD) has been shown in previous studies to display abnormal cerebral blood flow velocity (CBFV); however, the characteristics of cardio-cerebrovascular modulation are unknown. We aimed analyze using parameters from a supine-to-standing test. There 2 parts this study; Part 1, 125 participants with Hamilton Anxiety scale scores ≥14 were enrolled, and 33 age- sex-matched medically psychiatrically healthy volunteers recruited as control participants. Patients...
Objective: There is increasing evidence that high blood pressure (BP) levels and BP variability (BPV) over 24 hours or longer are associated with poor clinical outcomes in patients intracerebral hemorrhage (ICH). The objective of this study was to examine the association between different beat-to-beat parameters in-hospital outcomes. Methods: Patients a diagnosis acute spontaneous ICH were recruited consecutively prospectively September 2018 January 2019. Beat-to-beat recordings measured...
Objective.Hematoma expansion is closely associated with adverse functional outcomes in patients intracerebral hemorrhage (ICH). Prediction of hematoma would therefore be great clinical significance. We attempted to predict using a dual-modal machine learning (ML) strategy which combines information from non-contrast computed tomography (NCCT) images and multiple variables.Approach.We retrospectively identified 140 ICH (57 expansion) 5616 NCCT (2635 10 variables. The ML consists two steps....