A5100745712- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Ginseng Biological Effects and Applications
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Pharmacological Effects of Natural Compounds
- Traditional Chinese Medicine Analysis
- Thermal Regulation in Medicine
- Atrial Fibrillation Management and Outcomes
- Magnolia and Illicium research
- Atherosclerosis and Cardiovascular Diseases
- Heart Rate Variability and Autonomic Control
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Blood groups and transfusion
- Mesenchymal stem cell research
- Hepatitis Viruses Studies and Epidemiology
- Blood Pressure and Hypertension Studies
- Platelet Disorders and Treatments
- Blood properties and coagulation
- Sepsis Diagnosis and Treatment
- Liver Diseases and Immunity
Beijing Chao-Yang Hospital
2013-2025
Capital Medical University
2011-2025
China-Japan Friendship Hospital
2023-2025
Huazhong University of Science and Technology
2020-2025
Shanghai Public Health Clinical Center
2020-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2024
Xiyuan Hospital
2013-2024
Jiangnan University
2024
Jining Medical University
2024
Shandong Provincial QianFoShan Hospital
2008-2023
Severity stratification and prognostic prediction at early stage is crucial for reducing the rates of mortality patients with acute pancreatitis (AP). We aim to investigate predicting performance neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte (PLR), red-cell distribution width (RDW) combined severity scores (sequential organ failure assessment [SOFA], bed-side index AP [BISAP], Ranson criteria, physiology chronic health evaluation II [APACHE II]) severe (SAP) mortality.A total 406...
High platelet reactivity and gastric mucosal injury after aspirin (ASA) treatment are associated with poor compliance an increased risk of cardiovascular events. Panax notoginseng saponins (PNS) have been widely used for the coronary heart disease (CHD) in addition to antiplatelet drugs China; however, joint effect possible mechanism PNS ASA on activation remain unclear. This study was designed investigate combinational effects ASA, explore underlying via arachidonic acid (AA) metabolism...
Objective: To summarize the clinical characteristics and liver biochemical parameters of 324 cases admitted with novel coronavirus pneumonia in Shanghai area. Methods: Clinical data baseline to Public Health Center from January 20, 2020 February 24, were retrospectively analyzed. Patients divided into two groups based on status illness: mild type (mild typical) severe (severe critical).The differences described compared. The t-test Wilcoxon rank-sum test used for measurement data....
Background The intricate interaction between oxidative stress and atherosclerotic cardiovascular disease (ASCVD) is an essential area of research because the potential role homeostasis in regulating ASCVD risk. This study aimed to investigate relationship balance score (OBS) 10-years risk gain insight into how affects health. Methods cross-sectional analyzed National Health Nutrition Examination Survey (NHANES) 2011–2020 data (40–79 age group), exploring OBS’s link OBS categorized dietary...
Background and Aims: Acute-on-chronic liver failure (ACLF) is a highly dynamic syndrome. The objective of this study was to delineate the clinical course patients with HBV-ACLF develop model estimate temporal evolution disease severity. Methods: We enrolled eligible from 2 large, multicenter prospective cohorts. ACLF grade, organ failures, outcomes were assessed at multiple time points (days 1/4/7/14/21/28). Probabilities for transitions between these states death within 28 days calculated...
To investigate the effects of semaphorin 3A (sema 3A) on cardiac autonomic regulation and subsequent ventricular arrhythmias (VAs) in post-infarcted hearts.In order to explore functions sema hearts, lentivirus-Sema 3A-shRNA negative control vectors were delivered peri-infarcted myocardium rats respectively. Meanwhile, recombinant (0.9% NaCl solution) injected intravenously into infarcted test therapeutic potential 3A. Results indicated that levels higher hearts compared with sham rats....
Inflammation after myocardial infarction (MI) causes cardiac nerve sprouting and consequent ventricular arrhythmias (VAs). Macrophages, as major immune cells, are involved in the entire inflammation response process serve a link between sympathetic hyperinnervation by regulating growth factor (NGF) expression. Accumulating evidence shows that statins possess antiarrhythmogenic properties, aim of this study was to explore mechanism which atorvastatin ameliorates via macrophage...
XueShuanTong (XST) comprising therapeutically active ginsenosides, a lyophilized extract of Panax notoginseng roots, is extensively used in traditional Chinese medicine to treat ischemic heart and cerebrovascular diseases. Our recent study shows that treatment with XST inhibits shear-induced thrombosis formation but the underlying mechanism remained unclear. This aimed investigate hypothesis inhibited platelet aggregation via targeting mechanosensitive Ca 2+ -permeable Piezo1 channel by...
Previous observational studies have shown that the prevalence of cardiovascular diseases (CVDs) is related to particulate matter (PM). However, given methodological limitations conventional research, it difficult identify causality conclusively. To explore PM on CVDs and biomarkers, we conducted a Mendelian randomization (MR) analysis.In this study, obtained summary-level data for biomarkers including atrial fibrillation (AF), heart failure (HF), myocardial infarction (MI), ischemic stroke...
Acute kidney injury (AKI) is a common complication in heart failure (HF) patients. Patients with who experience renal tend to have poor prognosis. The objective of this study examine the correlation between occurrence AKI patients and different mean arterial pressure (MAP) trajectories, goal improving early identification intervention for AKI. A retrospective was conducted on using data from Medical Information Mart Intensive Care IV (MIMIC-IV). We utilized group-based trajectory modeling...
Inherited macrothrombocytopenia (IMT) is characterized by increased platelet volume. Using parameters, including count, mean volume (MPV), platelet-large cell ratio (P-LCR), and distribution width, to differentiate IMT from acquired thrombocytopenia (AT) in the Chinese population unclear. This study aimed evaluate these parameters determine optimal thresholds for early identification. single-center, retrospective case-control included patients 1 January 2022 31 2024. Age- sex-matched AT...
Understanding the regional HPV genotype profile is critical for informing targeted vaccination strategies and optimizing cervical cancer screening programs to enhance their effectiveness. This study investigated prevalence distribution of human papillomavirus (HPV) genotypes among women with squamous cell carcinoma (CSCC) in Linyi city, China, from 2015 2023. Data were obtained 606 histologically diagnosed CSCC at Cancer Hospital between January December DNA was extracted paraffin-embedded...