A5089666655- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Airway Management and Intubation Techniques
- Full-Duplex Wireless Communications
- Polyomavirus and related diseases
- Ultrasound in Clinical Applications
- Antenna Design and Analysis
- Esophageal and GI Pathology
- Pneumothorax, Barotrauma, Emphysema
- Respiratory Support and Mechanisms
- Parasites and Host Interactions
- Pneumocystis jirovecii pneumonia detection and treatment
- Climate Change and Health Impacts
- Trauma Management and Diagnosis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced Radiotherapy Techniques
- Medical Imaging and Pathology Studies
- Cancer Immunotherapy and Biomarkers
- Vascular Anomalies and Treatments
- Viral Infections and Vectors
- Thermal Regulation in Medicine
- Salivary Gland Tumors Diagnosis and Treatment
- Sarcoidosis and Beryllium Toxicity Research
- Mycobacterium research and diagnosis
The University of Texas MD Anderson Cancer Center
2018-2024
Aga Khan University Hospital
2023
Tecnológico de Monterrey
2023
Pulmonary Associates
2022
Greater Baltimore Medical Center
2016-2020
Johns Hopkins University
2008-2009
Johns Hopkins Medicine
2009
National Institute of Neurological Disorders and Stroke
2001-2006
National Institutes of Health
2001-2006
To explore knowledge and management of childhood fever among ethnically diverse parents identify opportunities for educational intervention, we administered a cross-sectional survey to convenience sample 487 children enrolled in 2 urban hospital-based pediatric clinics. Outcomes included parental definition fever, level concern, fever. Latino were least likely temperature as nonfebrile from 97-100.3°F (adjusted odds ratios [AOR] 0.06) or 100.4-107°F (AOR 0.52). African Americans believe that...
ABSTRACT JCV, a small DNA virus of the polyomavirus family, has been shown to infect glial cells central nervous system, hematopoietic progenitor cells, and immune system lymphocytes. A family binding proteins called nuclear factor-1 (NF-1) linked with site-coding specific transcription cellular viral genes replication some viruses, including JC (JCV). It is unclear which NF-1 gene product must be expressed by promote JCV multiplication. Previously, it was that elevated levels class D mRNA...
Facing an unprecedented surge of patient volumes and acuity, institutions around the globe called for volunteer healthcare workers to aid in effort against COVID-19. Specifically being sought out are retirees. But retired taking on significant risk themselves answering these calls. Aside from risks that come frontlines epidemic, they also at due their age comorbidities often accompany age. If, current or future COVID efforts, we as a society will be so bold exhort vulnerable population take...
Fever is a common childhood condition that often misunderstood and incorrectly managed by parents. This study uses questionnaire about fever administered to convenience sample of Spanish-speaking-only parents bringing their child hospital-based urban pediatric clinic. The elicits information definition cause fever, concerns methods temperature measurement, treatment modalities used the Latino have numerous misconceptions its role in illness. Educational interventions should target...
Background: Computed tomography to body divergence (CTBD) is one of the main barriers bronchoscopic techniques for diagnosis peripherally located lung nodules. Cone-beam CT (CBCT) guidance being rapidly adopted correct this phenomenon and potentially increase diagnostic outcomes. In trial, we hypothesized that addition mobile CBCT (m-CBCT) could improve rate tool in lesion (TIL) yield shape-sensing robotic-assisted bronchoscopy (SS-RAB). Methods: This was a prospective, single-arm study,...
Introduction Diagnostic biomarkers for immune checkpoint inhibitor pneumonitis (ICIP) are lacking. Bronchoalveolar lavage (BAL) lymphocytosis has been associated with ICIP, but studies have not evaluated BAL as a diagnostic biomarker ICIP. Purpose This study aimed to measure the association of cell percentage ICIP and test its performance biomarker. Methods We performed retrospective chart review 476 patients treated ICIs solid organ or hematologic malignancies who underwent between 2016...
The infectious cycle of the human polyomavirus JC (JCV) is ultimately regulated in cellular nuclei at level viral protein expression and genomic replication. Such activity prompted by interactions between variant nucleotide sequences within JCV regulatory region (promoter) transcription factors that bind specific DNA consensus sites. In previous work we identified an NF-1 class member, NF-1X, as a critical factor affecting host range. Within promoters, well other adjacently located AP-1...
The tyrosine kinase inhibitor pazopanib is used for treatment of sarcoma. Recent studies have suggested that the use may lead to development pneumothorax, an unexpected adverse effect in patients with sarcoma metastatic chest.We conducted a retrospective case control study metastases chest pneumothorax (cases) and without (controls). population was selected from tumor registry 1:4 (cases controls) ratio. primary outcome interest association between risk chest. Secondary objective evaluate...
Point-of-care (POC) ultrasonography is considered fundamental in emergency medicine training and recently has become a milestone critical care fellowship programs as well. Currently, there no such standard requirement for internal residency the United States. We present new case briefly review another at our institution – community hospital which house staff trained were able to uncover unexpected diagnoses that significantly changed patient outcomes. also growing evidence of application...
Pleuroscopy with pleural biopsy has a high sensitivity for malignant effusion (MPE). Because MPEs tend to recur, concurrent diagnosis and treatment of MPE during pleuroscopy is desired. However, proceeding directly at the time requires confidence in on-site diagnosis. The study's primary objective was create predictive model estimate probability pleuroscopy.A prospective observational multicentre cohort study consecutive patients undergoing conducted. We used logistic regression evaluate...
Narrow band imaging (NBI) has been widely applied for the evaluation of numerous disease conditions that present with increased vascularity mucosa, most often malignancies. It is increasingly being used in benign as well. We first case which NBI was used, rather, to detect areas bronchial hypovascularity due its ability increase visual contrast between normal and hypovascular mucosa. Endobronchial biopsy these nodules led diagnosis sarcoidosis. Had conventional white light alone utilized,...
Background Pleural infection is a common clinical problem resulting in prolonged hospitalization and increased mortality. In patients with active malignancy, management decisions are based on the need for further immunosuppressive therapies, ability to tolerate surgery, consideration of limited life expectancy. Identifying at risk death or poor outcomes very important as it will guide care. Study design methods This retrospective cohort study all malignancy empyema. The primary outcome was...
Early stage acute kidney injury (AKI) is an independent risk factor for increase in mortality. Accurate assessment of volume status a major challenge during the early stages renal injury. Determining based on history and physical exam lacks accuracy. Urine sodium free excretion (FENa) provide objective evidence intravascular when interpreted carefully helpful to delineate prerenal from intrinsic failure. In recent years point care ultrasound has been used assess status. Our team conducted...
Central airway obstruction often presents with narrowing of differing internal diameters. Conventional straight stents do not fit these airways well and are prone to migration. We present a series cases where hourglass-shaped silicone were customized intra-operatively obstructions both malignant non-malignant etiologies improve patient performance status. Modified hourglass versatile tool manage inoperable unique anatomical characteristics.
An 84-year-old man with hypertension and a history of deep venous thrombosis (on warfarin) was admitted shortness breath presumed to be due congestive heart failure. Echocardiogram performed the following day showed low-normal ejection fraction signs elevated right-sided pressures but otherwise normal. He improved diuretic therapy after few days found hypotensive concomitant rise in creatinine decreased urine output. This felt secondary over-diuresis he did not respond small boluses...