Pediatric pulmonary embolism (PE) is rare but associated with adverse outcomes. We aimed to characterize PE cases admitted in a tertiary hospital and evaluate sensitivity of selected diagnostic prediction tools.Retrospective, descriptive study from 2008 2020 using data collected records. Patients were grouped according severity setting (outpatients vs. inpatients). Links correlation demographic characteristics, risk factors, clinical presentation, management, outcomes analyzed. tools...

Abstract Background We evaluated different pain profiles as prospective predictors of multisite in 13‐year‐old adolescents (1300 girls and 1457 boys) enrolled Generation XXI, a birth cohort study Portugal. Methods Pain history was queried using the Luebeck Questionnaire through parent proxy‐ (ages 7 10) adolescent (age 13) self‐reports. estimated risk (2 or more sites) at age 13, according to previous experiences, including accumulation timing. defined five that combined adverse features...

To estimate agreement in the point prevalence of any pain, high-intensity pain and two or more sites according to parental child report.We conducted a prospective study 5639 children from Portuguese birth cohort - Generation XXI, where parents 7-year-old answered same questions at time. We assessed accuracy report, considering children's self-report as gold standard.At 7 years age, 499 (8.8% (95% confidence interval (CI) 8.1-9.6)) reported having time interview. Of those, 44.1% had (3.9% CI...

The prevalence of hypertension in the pediatric age range is estimated at 1–5% worldwide, with higher rates adolescence. Although primary more common, due to increasing obesity and metabolic syndrome among adolescents, secondary should be always considered excluded. We present case an adolescent a challenging diagnosis associated coarctation aorta Turner Mosaicism.

Abstract Pain is a distinctive burden in atopic dermatitis and recognized as an important highly prevalent symptom. It unknown if the presence of disease may sensitize children to adverse pain profiles long term. We aimed assess impact early-life dermatitis-like symptoms on at 10 years age. used data from 1302 874 participants Generation XXI birth cohort evaluated 6 15 months, respectively, years. Atopy-like since birth, including dermatitis, were collected ages months by interviewing...

Wolfram syndrome (WFS) is a neurological and endocrinological degenerative disorder, also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes Mellitus, progressive Optic Atrophy, Deafness) syndrome. It an autosomal recessive mostly involving the 1 gene (WFS1). The phenotypic pleiomorphism, rarity, molecular complexity complicate follow-up of these patients.We aimed to describe clinical characteristics 11 patients with this disorder. We retrospectively analysed all WFS diagnosed...

Extubation failure (EF) is characterized by the need for reintubation after removal of endotracheal tube. The prevalence in pediatric age estimated at 2-20%. Although causes are almost always multifactorial, EF has been associated with several risk factors and generally a worse prognosis higher morbidity. We aimed to characterize patients admitted Pediatric Intensive Care Unit (PICU) Tertiary Hospital. It was performed retrospective descriptive study cases, considering all children PICU...

Introduction: Pediatric pulmonary embolism (PE) is rare but associated with adverse outcomes. We aimed to characterize PE cases admitted in a tertiary hospital and evaluate sensitivity of diagnostic prediction tools. Methods: Retrospective, descriptive study from 2008 2020. Data was collected records. Patients were grouped according severity setting (outpatients, inpatients). Associations demographic characteristics, risk factors, clinical presentation, management outcomes analyzed. tools...

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<h3>Introduction</h3> A Diagnosis Related Groups is a patient classification system that standardizes prospective payment to hospitals considering the main and secondary diagnoses, surgical procedures, complications, patient's age sex discharge status. There are hospitalizations of normal duration, short admissions, long-term admissions prolonged according episode whose hospitalization time expected, lower, upper or greater than maximum threshold respective defined time, respectively. The...

Department of Pediatrics. Centro Materno Pediátrico, Hospitalar e Universitário de São João, Oporto, Portugal <h3>Introduction and aim</h3> Level III hospitals are the last resource health care, covering more complex patients. According to literature, these patients hospitalized often for longer. Long-term hospitalizations defined as episodes whose hospitalization time is equal or greater than upper threshold exception lower maximum DRG which they belong. We aim characterize long-term in...

<h3>Introduction</h3> Pediatric pain has been considered an important public health issue which motivates studies about a wide variety of dimensions around the world. Although epidemiological have increased over past years, information to characterize pediatric from population-based is still limited, more even when children reported their own pain. <h3>Aim</h3> We aim prevalence, localization and intensity experience in Generation XXI birth cohort (G21) at age 10 by children. <h3>Materials...

<h3>Introduction</h3> Malaria is a parasitic disease (<i>Plasmodium</i>) transmitted by <i>Anopheles</i> mosquitoes. The diagnose made after positive result in the rapid diagnostic test or presence of parasite blood smear. Complicated malaria, classified with clinical and laboratory criteria, medical emergency presupposes injectable treatment. In endemic countries it serious problem public health resource consumption. objective this study was intended to reality Paediatrics hospital...

A 31 +2 weeks gestational age, birthweight 1,490 g female was born after an emergency C-section due to abruptio placenta. The Apgar score 4/8/8, needing positive pressure followed by nasal continuous airway (NCPAP). One dose of poractant alfa administered in the first hour life. On day 4 (D4) life, 2D-echocardiogram performed a systolic murmur showed presence hemodynamically significant patent ductus arteriosus. After two cycles intravenous ibuprofen standard doses (three per cycle: 10...

PDA varies according to gestational age and birth weight; it is more frequent among girls too. According some series, about 30% of preterm infants with a weight below 1,500 g present hemodynamically significant (HS-PDA) in the first days life. Clinical course: On day 25 (D25) life, fluoroscopic exam confirmed diagnosis left hemidiaphragmatic paralysis. Due increase respiratory work despite support NCPAP for 18 X-ray repetition, we decided perform plication. She had good recovery after...

Abstract Background: Impaired sensitivity to thyroid hormone refers any process that negatively affects its action, including defects in transport, metabolism and action on the receptor. Resistance due beta-receptor mutations (RTH-beta) is most common form of this entity characterized by reduced response peripheral tissues hormone. The genetic variability cofactors involved explains heterogeneity resistance among affected individuals. Generally, patients with disorder, have increased levels...

Lupus erythematosus (LE) is a group of autoimmune disorders with clinical spectrum ranging from localized discoid lesions (DLE) to life-threatening systemic manifestations (1). Lupus panniculitis rare variant that may occur as separate disease or coexist DLE SLE (2). The incidence estimated between 1-3% LE cases, more prevalent (2:1) among females (5), especially at young age. It characterized by persistent, tender, and hard nodules on the face, arms, shoulders, breasts, buttocks. Healing...

Herpetic esophagitis (HE) is an uncommon condition in immunocompetent, and even less common young children. We present the case of a 6-year-old-child with HE food allergy. Recently association between atopic conditions, eosinophilic, herpetic has been suggested. Clinical suspicion key to diagnosis, especially persistent symptoms.

We present a male newborn referred to pediatric cardiology due heart murmur, whose echocardiographic evaluation showed an intrahepatic inferior vena cava interruption with azygos continuation and two small mesoseptal ventricular septal defects. Although mainly incidental, the early diagnosis of interrupted can be crucial avoid complications invasive vascular procedures.

Background. Type 1 diabetes (T1D) is the most common chronic metabolic disease among children and autoimmune process can induce development of additional diseases. We performed a retrospective study clinical records analytical determinations pediatric patients with T1D during five-year-period. Methods. identify 102 patients, similar gender distribution. In 98% was performed, at least, one tracking other disease. found positive autoantibodies in 31%: thyroid antibodies (n = 16), for celiac...