A5084898181- Pregnancy and Medication Impact
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Maternal Mental Health During Pregnancy and Postpartum
- Assisted Reproductive Technology and Twin Pregnancy
- Pharmacological Effects and Toxicity Studies
- Nanoparticles: synthesis and applications
- Prenatal Screening and Diagnostics
- Endometriosis Research and Treatment
- Fetal and Pediatric Neurological Disorders
- Connective tissue disorders research
- Reproductive Biology and Fertility
- melanin and skin pigmentation
- Reproductive Health and Contraception
- Elasticity and Material Modeling
- Graphene and Nanomaterials Applications
- Prenatal Substance Exposure Effects
- Breastfeeding Practices and Influences
- COVID-19 Impact on Reproduction
- Ectopic Pregnancy Diagnosis and Management
- Global Maternal and Child Health
- Eosinophilic Esophagitis
- Gene expression and cancer classification
- Cerebrospinal fluid and hydrocephalus
- Reconstructive Facial Surgery Techniques
Medical University of Graz
2013-2024
University of Graz
2002-2024
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2009
Swiss Epilepsy Center
2005
Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities study design and methodology. This aimed examine patterns factors associated with medications from a multinational perspective, emphasis type of utilised indication for use.Cross-sectional, web-based performed within the period 1 October 2011 29 February 2012. Uniform collection drug utilisation data was via an anonymous online questionnaire.Multinational Europe (Western, Northern...
An increasing and early-onset use of immunosuppressives biologics has become more frequently seen among patients with inflammatory bowel diseases (IBD) rheumatic disorders. Many women in their childbearing years currently receive such medications, some them an interdisciplinary setting. questions arise already pregnant or wishing to conceive respect continuing discontinuing treatment, the risks borne by newborns mothers long-term safety. Together Austrian Society Rheumatology Rehabilitation,...
Background No previous studies have explored how closely women follow their psychotropic drug regimens during pregnancy. This study aimed to explore patterns of and factors associated with low adherence medication Methods Multinational web-based was performed in 18 countries Europe, North America, Australia. Uniform data collection ensured via an electronic questionnaire. Pregnant were eligible participate. Adherence measured the 8-item Morisky Medication Scale (MMAS-8). The Beliefs about...
A thorough understanding of nanoparticle bio-distribution at the feto-maternal interface will be a prerequisite for their diagnostic or therapeutic application in women childbearing age and teratologic risk assessment. Therefore, tissue interaction biocompatible dendritic polyglycerol nanoparticles (dPG-NPs) with first- trimester human placental explants were analyzed compared to less sophisticated trophoblast-cell based models. First-trimester explants, BeWo cells primary trophoblast from...
This study aimed at exploring the prevalence of self-reported antenatal and postnatal depressive symptoms by severity across multiple countries association between antidepressant treatment in pregnancy symptom severity.This was a multinational web-based conducted 12 European (n=8069). Uniform data collection ensured via an electronic questionnaire. Pregnant women any gestational week mothers children with <1 year age could participate. We used Edinburgh Postnatal Depression Scale (EPDS) to...
<h3>Background/aims</h3> To gain more knowledge about presence and dermatological associations of iris nevi as well possible pathways involved in the formation nevi. <h3>Methods</h3> We conducted a prospective, interdisciplinary observational study. Presence, morphology, topography cutaneous factors indicating sun-exposure were noted. <h3>Results</h3> A total 632 participants including 360 (57%) women examined. Of those, 26 subjects revealed 27 According to current classification, all judged...
Background. The phenotypes of patients with the recently discovered, dominant, ETV6-linked leukaemia predisposition and familial thrombocytopenia syndrome are variable, exact mechanism leukaemogenesis remains unclear. Patients Methods. Here, we present novel clinical laboratory seven individuals from three families ETV6 germline mutations a refined genetic analysis one child additional high-hyperdiploid acute lymphoblastic (HD-ALL), aiming to elucidate second oncogenic hits. Results. Four...
In early human gestation, maternal arterial blood flow into the intervillous space of developing placenta is obstructed by invaded trophoblasts, which form cellular plugs in uterine spiral arteries. These trophoblast have recently been described to be loosely cohesive with clear capillary-sized channels 7 weeks gestation. Here, we analysed localisation platelets at maternal-foetal interface first trimester pregnancy, and tested hypothesis whether HLA-G, primarily expressed extravillous...
Highly diluted solutions of Gentian Violet and Evans Blue were used to visualize the elastin network in viable porcine right common carotid artery (RCCA) preparations. The two simple, alternative methods staining applied proximal, intermediate, distal sections RCCA under various experimental conditions. These included state vessel wall soon after excision, relaxed smooth muscle condition preconditioning, during vasoconstriction. Micrographs arterial rings, sectors, axial strips show that is...
Angiotensin II receptor 1 blockers are commonly used to treat hypertension in women of childbearing age. While the fetotoxic effects these drugs second and third trimesters pregnancy well documented, their possible impacts on placenta development early gestation unknown. Candesartan, a member this group, also acts as peroxisome proliferator-activated gamma (PPARγ) agonist, key regulator shown be important for placental development. We have previously that trophoblasts do not express...