A5079696064- Bacterial Identification and Susceptibility Testing
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Streptococcal Infections and Treatments
- Mycobacterium research and diagnosis
- Infective Endocarditis Diagnosis and Management
- Infection Control in Healthcare
- Pneumocystis jirovecii pneumonia detection and treatment
- Bartonella species infections research
- Actinomycetales infections and treatment
- Infectious Diseases and Mycology
- Herpesvirus Infections and Treatments
- Antibiotic Use and Resistance
- Infection Control and Ventilation
- Urinary Tract Infections Management
- Antimicrobial Resistance in Staphylococcus
- Orthopedic Infections and Treatments
- Clostridium difficile and Clostridium perfringens research
- Nosocomial Infections in ICU
- Central Venous Catheters and Hemodialysis
- Drug-Induced Adverse Reactions
- Tuberculosis Research and Epidemiology
- Acne and Rosacea Treatments and Effects
- Peripheral Neuropathies and Disorders
- Long-Term Effects of COVID-19
Allegheny Health Network
2014-2025
Allegheny General Hospital
2015-2024
Drexel University
2022-2023
GlaxoSmithKline (United States)
2020
Temple University
2017
Astellas Pharma (Japan)
2016
Astellas Pharma (Canada)
2016
Office of Infectious Diseases
2012
University of Chicago
2009-2010
Society for Healthcare Epidemiology of America
2010
We present a case of Guillain- Barré Syndrome (GBS) in patient with confirmed COVID-19 infection. GBS commonly encountered after an antecedent trigger, most To date, only one associated this infection has been described. Clinicians should consider entity since it may warrant appropriate isolation precautions especially who not primarily typical constitutional and respiratory symptoms COVID-19.
Safety monitoring is of paramount importance for vaccines authorized emergent use (EUA) by the US Food and Drug Administration (FDA) against SARS-CoV-2. Mass immunization an essential tool to end current pandemic, but vaccine surveillance necessary identify any potentially associated harms. At same time, probability temporal bias should be borne in mind before making conclusions about causality between attributable undesired effect. We report a case Guillain-Barré syndrome after first dose...
To evaluate the feasibility of using an electronic hand hygiene surveillance and feedback monitoring device.A 2-phase pilot study included initial direct observation practices as part routine hospital quality assurance (phase I) subsequent device II).A 700-bed tertiary care teaching hospital.Phase I a convenience sample healthcare workers. Phase II 7 medical interns registered nurses recruited through email at work-related meetings.During phase I, workers were directly observed patient room...
Gram-negative bacteria (GNB) are a leading cause of bloodstream infections (BSI) and management is complicated by antibiotic resistance. The Accelerate Pheno™ system (ACC) can provide rapid organism identification antimicrobial susceptibility testing (AST).
Buschke-Lowenstein tumor is a relatively rare sexually transmitted disease. It neoplasm of the anogenital region which has benign appearance on histopathology but locally destructive. carries high recurrence rate and significant potential for malignant transformation. Human papilloma virus been implicated as an etiologic agent this tumor. Since disease no controlled studies exist, radical excision lesion generally recommended first line therapy close vigilance followup are essential. We have...
Abstract Background Enterococcus spp. represent a frequent cause of blood stream infections in the United States. We wanted to gather data on clinical characteristics and outcomes associated with enterococcal bloodstream encountered at our quaternary care integrated health network.Table 1:Patient demographics comorbiditiesBaseline patients reviewed study, including their demographic underlying medical history Methods conducted multicenter retrospective chart review from 2022 2023...
Abstract Background Catheter associated urinary tract infections (CAUTIs) have significant clinical and financial impact on the US healthcare system. In a systematic review published in 2018, attributable cost of CAUTI was estimated to exceed $1000 (1). Indwelling catheters increase risk for CAUTIs proportionate length catheter use (figure 1). External Urethral Catheters (EUC) potential reduce CAUTIs. We conducted this quality improvement project study EUC ICUs at our institution. Figure 1....
Sepsis is a severe and often life-threatening condition which can lead to widespread organ dysfunction, septic shock, even death. Antimicrobials are critical in improving outcomes for patients with sepsis. This chapter details the general principles of antimicrobial therapy, appropriate selection de-escalation antimicrobials, challenges stewardship.
Abstract Objective: To evaluate the impact of implementing a multi-step Clostridioides difficile infection (CDI) testing algorithm on hospital-onset (HO)-CDI rates and clinical outcomes. Design: Retrospective pre-intervention/post-intervention study. Setting: Two academic hospitals in Pittsburgh, Pennsylvania. Methods: In pre-intervention period, standalone polymerase chain reaction (PCR) assay was used for diagnosing CDI. post-intervention positive PCR assays were reflexed to glutamate...
Abstract Background Electronic Health Record (EHR) implementation has created an unprecedented library of patient data. Data extraction tools provide opportunity to retrieve clinico-epidemiological information on a wide scale. Slicer Dicer is data exploration tool in the EPIC EHR that allows one customize searches large populations. This software contains variety models present de-identified from EPIC’s Caboodle database. We explored applicability and potential utility this utilizing...
Propionibacterium acnes infections are likely under-recognized and underreported. This is partly because of low clinical suspicion, perceived non-pathogenicity, or lack adequate culture incubation time. We conducted a study to assess the optimal period recover P. from specimens acquired during workup suspected infections.A 5-year retrospective chart review was between January 2010 December 2014 at single tertiary-care hospital. All patient cases which recovered were included for analysis....
Abstract Objective: Central-line–associated bloodstream infection (CLABSI) surveillance in home infusion therapy is necessary to track efforts reduce infections, but a standardized, validated, and feasible definition lacking. We tested the validity of home-infusion CLABSI feasibility acceptability its implementation. Design: Mixed-methods study including validation cases semistructured interviews with staff applying these approaches. Setting: This was conducted 5 large agencies prevention...
Gram-negative microorganisms are uncommon pathogens responsible for infective endocarditis. Pseudomonas mendocina, a water-borne and soil-borne bacterium, was first reported to cause human infection in 1992. Since then, it has rarely been as pathogen the literature. We describe case of native valve endocarditis due P. mendocina USA.A 57-year-old white man presented with bilateral large leg ulcers, fever, marked leukocytosis. His past medical history included gout chronic alcohol use....