- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Micro and Nano Robotics
- Differential Equations and Numerical Methods
- Innovative Microfluidic and Catalytic Techniques Innovation
- Dark Matter and Cosmic Phenomena
- 3D Printing in Biomedical Research
- Particle physics theoretical and experimental studies
- Nanofabrication and Lithography Techniques
- Matrix Theory and Algorithms
- Nutrition and Health in Aging
- COVID-19 and Mental Health
- Pancreatitis Pathology and Treatment
- Numerical methods in inverse problems
- Electromagnetic Scattering and Analysis
- Numerical methods for differential equations
- Acoustic Wave Resonator Technologies
- Autonomous Vehicle Technology and Safety
- Water Quality Monitoring and Analysis
- Cosmology and Gravitation Theories
- Astrophysics and Cosmic Phenomena
- Liver Disease and Transplantation
- Orbital Angular Momentum in Optics
- Mercury impact and mitigation studies
- COVID-19 Impact on Reproduction
Sinochem Group (China)
2022-2025
Massachusetts Institute of Technology
2023-2024
Tsinghua University
2012-2023
Washington University in St. Louis
2018-2023
Methodist Dallas Medical Center
2023
Texas Liver Institute
2023
Technical University of Munich
2023
Clinical Research Institute
2022
Purple Mountain Observatory
2021
Chinese Academy of Sciences
2021
We report a label-free acoustic microfluidic method to confine single, cilia-driven swimming cells in space without limiting their rotational degrees of freedom. Our platform integrates surface wave (SAW) actuator and bulk (BAW) trapping array enable multiplexed analysis with high spatial resolution forces that are strong enough hold individual microswimmers. The hybrid BAW/SAW tweezers employ high-efficiency mode conversion achieve submicron image while compensating for parasitic system...
Recently, there has been a lot of interest in using gold nanoparticles (GNPs) for biomedical applications due to their biocompatibility. To increase GNP cell uptake and circulation half-life, improve its bio-distribution vivo, we chose coat GNPs with 1-palmitoyl-2-oleoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (POPG) polyethylene glycol (PEG). Two different methods were used synthesize POPG-GNPs or PEG-GNPs, but the resulting nanoparticle sizes morphologies similar. Under same...
Glass-based surface acoustic wave (SAW) devices enable trapping and analysis of swimming <italic>Chlamydomonas reinhardtii</italic> cells without the excessive heating associated with PDMS-based SAW devices.
Knowledge, attitude, and practices (KAP) have been widely used during times of pandemic to quantify locate gaps care pandemics. Using this tool, we can identify target populations who underwent solid organ transplant (SOT) bolster preventative in these patients COVID-19.An institution-based cross-sectional study was conducted between June 1, 2020 30, 2021 on a liver and/or kidney at Methodist Dallas Medical Center Dallas, Texas, USA. A KAP questionnaire 26 questions about COVID-19 designed...
Microfluidic technologies are increasingly implemented to replace manual methods in biological and biochemical sample processing. We explore the feasibility of an acoustofluidic trap for confinement microparticle reaction substrates against continuously flowing reagents chemical synthesis detection applications. Computational models used predict flow ultrasonic standing wave fields within two longitudinal bulk acoustic (LSBAW) microchannels operated 0.5–2.0 MHz range. Glass (gLSBAW) silicon...
For the newly discovered $W$-boson mass anomaly, one of simplest dark matter (DM) models that can account for anomaly without violating other astrophysical/experimental constraints is inert two Higgs doublet model, in which DM ($m_{S}$) found to be within $\sim 54-74$ GeV. In this annihilation via $SS\to b\bar{b}$ and WW^{*}$ would produce antiprotons gamma rays, may excesses identified previously both particles. Motivated by this, we re-analyze AMS-02 antiproton Fermi-LAT Galactic center...
We introduce an acoustic microfluidic device architecture that locally augments the pressure field for separation and enrichment of targeted microparticles in a longitudinal trap. Pairs pillar arrays comprise "pseudo walls" are oriented perpendicular to inflow direction. Though sample flow is unimpeded, support half-wave resonances correspond array gap width. Positive contrast particles supracritical diameter focus nodal locations held against drag from bulk fluid motion. Thus, standing wave...
In this paper, two point boundary value problems of 2mth‐order nonlinear differential equations are considered. The existence the solution and a new iterative algorithm which is large‐range convergent proposed for in reproducing kernel space. advantage approach must lie fact that, on one hand, arbitrary fixed initial function, method convergent. On other approximate its derivatives converge uniformly to exact derivatives, respectively. Some examples displayed demonstrate computation...
Micropatterning technology offers powerful methods for biological analyses at the molecular level, enabling investigation of cell heterogeneities, as well high throughput detection. We herein propose an approach single-cell patterning. The substrate was prepared using micro fabrication and surface modification processes, patterning template bovine serum albumin streptavidin, which can be employed any molecules containing biotin. Subsequent to photolithography, etching, chemical vapor...
Bioconjugates are important next-generation drugs and imaging agents. Assembly of these increasingly complex constructs requires precise control over processing conditions, which is a challenge for conventional manual synthesis. This inadequacy has motivated the pursuit new approaches efficient, controlled modification high-molecular-weight biologics such as proteins, carbohydrates, nucleic acids. We report novel, hands-free, semiautomated platform synthetic manipulation biomolecules using...
Background Severe acute pancreatitis (SAP) has a mortality rate as high 40%. Early identification of SAP is required to appropriately triage and direct initial therapies. The purpose this study was develop prognostic model that identifies patients at risk for developing managed according guideline-based standardized early medical management (EMM) protocol. Methods This single-center included all diagnosed with (AP) the EMM protocol Methodist Acute Pancreatitis Protocol (MAPP) between April...
DArk Matter Particle Explorer (DAMPE), a space-borne high energy cosmic ray and gamma-ray detector, has surveyed the whole sky for five years collected more than 220,000 photons above 2 GeV since launching on Dec. 17, 2015. The instrument response functions (IRFs) are derived dedicated software named DmpST is developed data analysis of DAMPE. Here we present method DAMPE bright sources search spectral analyses these sources.
Droplet spraying is utilized in diverse industrial processes and biomedical applications, including nanomaterial synthesis, biomaterial handling, inhalation drug delivery. Ultrasonic droplet generators transfer energy into bulk liquids using acoustic waves to disrupt the free liquid surface fine microdroplets. We previously established a method combining ultrasonic actuation, resonant operation, wave focusing for efficient of various (e.g., low tension fuels, high viscosity inks, suspensions...
Introduction: Frailty is widely recognized as an important tool in the assessment of patients with end stage liver disease (ESLD). The only current metric used by United Network for Organ Sharing to assess frailty Karnofsky Performance Status (KPS) score, a subjectively assigned value based on perceived functional status. index (LFI) instead integrates several objective instruments (i.e. grip strength, chair strands, and balance testing). While previous studies have shown that higher LFI...
Introduction: Frailty assessment is a critical component of liver transplant (LT) evaluation. has been defined through various subjective and objective tools, ranging from an “eyeball test” to 6-minute walk test; however, no single test emerged as universal standard. The frailty index (LFI) integrates several instruments (i.e., grip strength, chair stands balance testing) that have utilized in other fields. Previous studies showed higher LFI scores are associated with waitlist mortality...
<title>Abstract</title> Rapid industrialization has led to centralized industrial parks, particularly for heavily polluting industries like coatings, which generate significant volumes of hazardous wastewater. Effective influent management and process monitoring are essential the stable operation wastewater treatment plants in these parks. This study collected samples from factories a coating park its plant characterize water quality. Fluorescence spectra were analyzed using Parallel Factor...