- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Pluripotent Stem Cells Research
- Animal Genetics and Reproduction
- Ovarian function and disorders
- Renal and related cancers
- Reproductive biology and impacts on aquatic species
- Reproductive Health and Technologies
- CRISPR and Genetic Engineering
- Tissue Engineering and Regenerative Medicine
- Seed Germination and Physiology
- Reproductive Physiology in Livestock
- Mesenchymal stem cell research
- Animal Nutrition and Physiology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA Interference and Gene Delivery
- Saffron Plant Research Studies
- Magnetic and Electromagnetic Effects
- Reproductive System and Pregnancy
- Cardiac and Coronary Surgery Techniques
- 3D Printing in Biomedical Research
- Epigenetics and DNA Methylation
- COVID-19 Impact on Reproduction
- Bee Products Chemical Analysis
- Prenatal Screening and Diagnostics
Academic Center for Education, Culture and Research
2016-2025
Royan Institute
2016-2025
Shahid Beheshti University
2014
Tarbiat Modares University
2007-2010
University of Science and Culture
2009
Agricultural Biotechnology Research Institute of Iran
2009
Hyaluronic acid (HA) plays a prominent role in various aspects of reproductive biology and assisted technologies (ART). This review describes the multifaceted influence HA, ranging from primordial germ cell migration, ovarian follicle development, ovulation females to sperm structure, physiology, motility, capacitation males. In addition, HA also an important fertilization promotes embryo implantation by mediating cellular adhesion communication within uterus. Against this physiological...
Amino acids seem to be crucial components for semen freezing extender due antioxidant properties. Therefore, this study aimed assess motility parameters, membrane integrity, intracellular reactive oxygen species (ROS), mitochondrial potential (MMP) and DNA damage detect the optimum concentrations of cysteine glutamine buffalo cryopreservation. Twenty ejaculates four bulls were diluted in tris-egg yolk divided into seven equal groups consisting (5, 7.5 10 mmol), (10, 15 20 mmol) no additive....
Summary Although vitamin D deficiency is one of the most common health problems throughout world, including Iran, conflicting information exists on potential association between serum levels and semen quality. This study intended to evaluate [25( OH ) D3] with quality hormones in Iranian subfertile men. We also compared mean hormone normospermic men oligoasthenoteratozoospermia ( OAT cross‐sectional was conducted 278 who were referred Royan Infertility Clinic (Tehran, Iran) from March...
The CD133(+) bone marrow cell (BMC) population includes primitive multipotent stem cells which induce neoangiogenesis. Studies suggested transplantation of these to infarcted myocardium can have a favorable impact on tissue perfusion and contractile performance. We assessed the feasibility, safety functional outcomes autologus BMC during coronary artery bypass grafting (CABG) in patients with recent myocardial infarction. In prospective, nonrandomized, open-label study, 27 infarction...
The aim of this study was to investigate the effects several dietary fatty acids (FAs) on semen quality and blood parameters in rams. We gave diet-supplemented treatments (35 g day(-1) ram(-1)) by C16:0 (palm oil), C18:2 [sunflower oil (SO)] an n-3 source [fish (FO)] 12 rams, who were fed for 15 weeks during their breeding season. Semen collected once per week. samples extended with Tris-based cryoprotective diluents, then cooled 5 °C stored liquid nitrogen. Positive responses seen FO after...
Ovarian tissue transplantation is performed to preserve fertility in patients undergoing chemotherapy and radiotherapy. However, ischemia/reperfusion (IR) injury free radical production occurring during the revascularization of transplanted are major limitations this procedure. The aim study was investigate effect erythropoietin (EPO) as an antioxidant on oxidative stress ovary survival following transplantation. Naval Medical Research Institute (NMRI) mice (4-5 weeks old) were divided into...
Cryopreservation of semen requires optimized conditions to minimize the harmful effects various stresses. The main approach for protection sperm against stress is based on use antioxidants and cryoprotectants, which are described as defensive methods. Recently, application controlled mild stressors has been de- scribed activation a temporary response in oocyte, embryo somatic cells. In this study sub-lethal oxidative induced by precise concentrations nitric oxide (NO) evaluated during...
Abstract Background Subfertility in obese and diabetic men during the reproductive age is evident, but mechanisms by which obesity diabetes mellitus cause male infertility are not entirely understood . The current study aimed to evaluate effects potential of on fertility. Methods We enrolled control = 40, Lean-DM 35, Obese-DM 35 individuals. obesity-associated markers, hormonal lipid profile, inflammatory indices, semen analysis were assessed four experimental groups. Results Our finding...
Microfluidic systems have been extensively studied in recent years as potential alternatives for problematic conventional methods of sperm selection. However, despite the widespread use simple straight channels these systems, impact channel geometry on selected quality has not thoroughly investigated. To explore this further, we designed and fabricated serpentine microchannels with different radii curvature, inspired by tortuous structure cervix. Our results showed that presence gentle...
5-Aza-2′-deoxycytidine (AzC), trichostatin A (TSA), and its natural mimetic, sodium butyrate (NaB), are antineoplastic drugs that can modify the epigenetic status of donor cells prior to somatic cell nuclear transfer (SCNT). In this study, we used fibroblast treated with these investigate direct indirect effects induced changes in DNA methylation acetylation lysine 9 residue histone H3 (H3K9). Additionally, assayed cellular characteristics (cell growth, proliferation, cycle progression,...