A5051798464- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Pluripotent Stem Cells Research
- Ovarian function and disorders
- Reproductive Health and Technologies
- Animal Genetics and Reproduction
- CRISPR and Genetic Engineering
- Adipose Tissue and Metabolism
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- RNA Interference and Gene Delivery
- Assisted Reproductive Technology and Twin Pregnancy
- Electrospun Nanofibers in Biomedical Applications
- Renal and related cancers
- Tissue Engineering and Regenerative Medicine
- Peroxisome Proliferator-Activated Receptors
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Bone Tissue Engineering Materials
- Birth, Development, and Health
- Selenium in Biological Systems
- Reproductive System and Pregnancy
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
Royan Institute
2016-2025
Academic Center for Education, Culture and Research
2016-2025
Isfahan Fertility and Infertility Center
2016-2025
Soil Conservation and Watershed Management Research
2012-2025
Agricultural Research & Education Organization
2018-2025
Isfahan University of Medical Sciences
2015-2024
University of Tehran
2024
University of Isfahan
2016-2023
Biotechnology Research Center
2019-2023
Ragheb Esfahani Institute
2022-2023
ABSTRACT We describe a fluorimetric method for measuring the level of H2O2 in individual mouse oocytes and early embryos. Levels are low but detectable unfertilized recovered freshly from female reproductive tract. The levels cleaving embryos (1-cell to 8-cell stages) immediately after recovery tract seem be slightly higher later stage examined. However, when cultured vitro 1-cell or 2-cell stage, rise reach mid-2-cell remain elevated until they enter 4-cell stage. No equivalent elevation is...
Fabrication of scaffolds with suitable chemical, mechanical, and electrical properties is critical for the success nerve tissue engineering. Electrical stimulation was directly applied to electrospun conductive nanofibrous enhance regeneration process. In present study, nanofibers were prepared by mixing 10 15 wt% doped polyaniline (PANI) poly (epsilon-caprolactone)/gelatin (PG) (70:30) solution (PANI/PG) electrospinning. The fiber diameter, pore size, hydrophilicity, tensile properties,...
Infertile men have higher levels of semen reactive oxygen species (ROS) than fertile men. High ROS can cause sperm dysfunction, DNA damage and reduced male reproductive potential. This study investigated the effects supplementation with N-acetyl-cysteine (NAC) on quality, chromatin integrity oxidative stress in infertile The was carried out unit ACECR Infertility Research Center, Qom, Iran. patients consisted 50 asthenoteratozoospermia who received NAC (600 mg/d) orally for 3 months, after...
Tissue engineering techniques using a combination of polymeric scaffolds and cells represent promising approach for nerve regeneration. We fabricated electrospun by blending Poly (3-hydroxybutyrate) (PHB) (3-hydroxy butyrate-co-3- hydroxyvalerate) (PHBV) in different compositions order to investigate their potential the regeneration myelinic membrane. The thermal properties nanofibrous blends was analyzed differential scanning calorimetry (DSC), which indicated that melting glass...
The mammalian retina contains multiple cellular layers, each carrying out a specific task. Such controlled organization should be considered as crucial factor for designing retinal therapies. maintenance of layered complexity through the use scaffold-free techniques has recently emerged promising approach clinical ocular tissue engineering. In an attempt to fabricate such model, we are proposing herein unique inkjet bioprinting system applied deposition photoreceptor cells (PRs) layer on top...
ABSTRACT The increase in production of reactive oxygen species such as H2O2 at the G2/M phase second cell cycle may be related to vitro block development mouse 2-cell embryos. occurrence rise is independent activation embryonic genome and passage through S, G2 M phases first G1 cycle, but does require unfertilized oocyte. produced via dismutation superoxide by enzyme dismutase. Production mitochondrial, NADPH-oxidase xanthine/xanthine oxidase systems has been investigated. evidence suggests...
The effect of iron and chelators on the development mouse embryo in vitro from 1-cell stage to blastocyst has been investigated. An adverse was found. high affinity chelator, desferal, also blocked development, whilst transferrin (whether as apoprotein or saturated with iron), DETAPAC EDTA promoted development. addition permitted embryos strains normally exhibiting 2-cell block. Under such circumstances both rate embryonic proportion reaching approached levels found vivo. Based these...
Summary. Analysis over the first 48 h of development in vitro from one-cell stage to early four-cell indicated that (i) ethylenediaminetetraacetic acid (EDTA) exerts major beneficial effect on culture blastocyst F1 and MF1 embryos, (ii) glutamine assists MF1, but not F1, embryos probably functions as part a metabolic response oxidative damage mitochondria (iii) exposure glucose at some time during cleavage is essential for full blastocysts. None conditions examined affected significantly...