A5029795078- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- SARS-CoV-2 and COVID-19 Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pediatric health and respiratory diseases
- Cystic Fibrosis Research Advances
- Inhalation and Respiratory Drug Delivery
- COVID-19 Clinical Research Studies
- Mycobacterium research and diagnosis
- Long-Term Effects of COVID-19
- Lung Cancer Treatments and Mutations
- Nutrition, Genetics, and Disease
- COVID-19 and Mental Health
- Infectious Diseases and Mycology
- Inflammatory Myopathies and Dermatomyositis
- Esophageal and GI Pathology
- IL-33, ST2, and ILC Pathways
- Antifungal resistance and susceptibility
- Pneumocystis jirovecii pneumonia detection and treatment
- Actinomycetales infections and treatment
- Neurogenetic and Muscular Disorders Research
- Autoimmune and Inflammatory Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Dupuytren's Contracture and Treatments
- Infectious Diseases and Tuberculosis
University Hospital Centre Zagreb
2013-2023
Opća Bolnica Zadar
2019
The patients with hematological malignancies are a vulnerable group to COVID-19, due the immunodeficiency resulting from underlying disease and oncological treatment that significantly impair cellular humoral immunity. Here we report on beneficial impact of passive immunotherapy convalescent plasma treat prolonged, active COVID-19 infection in patient history nasopharyngeal diffuse large B-cell lymphoma treated therapy inducing substantial impairment particularly arm immune system. specific...
Aim- To compare the effectiveness of different biologic medications for treatment severe asthma. We retrospectively collected data on 74 patients treated with one four biologics (omalizumab, mepolizumab, reslizumab, or benralizumab) at Jordanovac Clinic Pulmonary Diseases, Zagreb, Croatia least two years. The were compared in terms number exacerbations, dose oral corticosteroids (OCS), asthma control test (ACT), forced expiratory volume 1 second (FEV1), vital capacity, fraction exhaled...
During the ongoing COVID-19 epidemic many efforts have gone into investigation of SARS-CoV-2-specific antibodies as possible therapeutics. Currently, conclusions cannot be drawn due to lack standardization in antibody assessments. Here we describe an approach establishing characterisation emergent times which would, if followed, enable comparison results from different studies. The key component is a reliable and reproducible assay wild-type SARS-CoV-2 neutralisation based on banking system...
Although the antineoplastic agent bleomycin is known for more than 50 years, its exact pharmacological and side-effect mechanisms remain incompletely understood. The major limitation of therapy risk pulmonary toxicity which can be diverse, potentially fatal in 10% patients. optimal treatment lung has not been established no clinical trials have performed. Here we present first successful case report nintedanib a patient with bleomycin-induced injury (BILI). prevention, early diagnosis,...
Lung transplantation is a therapeutic option for the treatment of advanced lung disease. The risk pulmonary infections increased in transplant recipients. We report case coinfection with Mycobacterium tuberculosis and Nocardia species recipient.
<b>Introduction:</b> Hypersensitivity pneumonitis (HP) is an ILD characterized by a complex immunological reaction of the lung parenchyma in response to repetitive inhalation sensitized allergen. Patients with HP and presence fibrosis have worse outcome. <b>Aim objectives:</b> To evaluate tretment annual change function tests patients fibrotic non-fibrotic HP. <b>Methods:</b> In this retrospective, observational study, data were collected from treated our Clinic during last 10 years. We...
Aspergillosis includes a group of disorders caused by Aspergillus species that affect the respiratory system most commonly. The clinical spectrum aspergillosis is divergent. Allergic bronchopulmonary result hypersensitivity to antigens. Although it known for many years, pathogenesis not entirely clarified and there are no exact diagnostic criteria. results delay, incompletely management can cause serious disability. Keywords: allergic; bronchopulmonary; aspergilosis; asthma.
Currently in Croatia, there are 275 severe asthma patients treated with biological therapy. Most of them (201) receiving anti-IL5 To assess the outcomes most used therapy we conducted a real-life study, including 41 at Clinical Center for Lung Diseases Jordanovac. Some parameters to were: number annual exacerbations asthma, disease control measured by ACT scale, FeNO, lung function parameters, and corticosteroid dose reduction. Results: 41 were three different agents – mepolizumab...