A5024393356- Synthesis and biological activity
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Urinary Tract Infections Management
- COVID-19 Clinical Research Studies
- Synthesis of Organic Compounds
- Phytochemistry and Biological Activities
- Phytochemicals and Antioxidant Activities
- Neonatal and Maternal Infections
- Sirtuins and Resveratrol in Medicine
- Antibiotic Resistance in Bacteria
- Listeria monocytogenes in Food Safety
- Iron Metabolism and Disorders
- Bacterial Identification and Susceptibility Testing
- Bioactive natural compounds
- Coconut Research and Applications
- Pediatric Urology and Nephrology Studies
- Bee Products Chemical Analysis
- Dietary Effects on Health
- Synthesis and Characterization of Heterocyclic Compounds
- Nosocomial Infections in ICU
- Computational Drug Discovery Methods
- Pregnancy and preeclampsia studies
- Antibiotic Use and Resistance
University of Ha'il
2022-2025
Middle Tennessee State University
2017-2020
While it is reported that COVID-19 patients are more prone to secondary bacterial infections, which strongly linked the severity of complications disease, coinfections associated with not widely studied. This work aimed investigate prevalence and antibiotic resistance profiles among hospitalised patients. Age, gender, weight, identities, sensitivity were collected retrospectively for 108 admitted intensive care unit (ICU) non-ICU ward a single center in Saudi Arabia. ICU (60%) showed...
The prevalence of non-small cell lung cancer (NSCLC), particularly in the Eastern Region Saudi Arabia, is concerning and highlights need for novel treatments, despite recent progress NSCLC treatment. Plant-derived natural compounds, such as those found Catharanthus roseus, have shown promising results research. By employing cutting-edge computational analysis techniques, molecular docking network pharmacology, study aimed to understand mechanism action compounds isolated from C. roseus....
Infections caused by multi-drug-resistant bacteria in patients with chronic diseases have been associated high mortality and morbidity. While few reports evaluated bacterial infections multiple disease patients, the focus of current study was to investigate prevalence susceptibility profiles causative strains among various groups suffering from diseases. Microbiological cancer, diabetes mellitus, cardiovascular diseases, kidney skin burns were retrospectively collected a tertiary hospital...
Introduction Anaemia remains a major public health issue. This condition adversely impacts women of reproductive age, especially in low-income countries. Although there is an ongoing global effort to reduce anaemia prevalence, progress slow and uneven. exhibits unique patterns the Eastern Mediterranean Region (EMR) due this region’s economic disparities variations access services. study examined trends prevalence among pregnant nonpregnant EMR by national income. Material methods...
The level of association between hemoglobin level/anemia and obesity during pregnancy is not yet fully understood. A cross-sectional study was conducted in Hail Maternity Hospital northern Saudi Arabia from March to May 2023 assess the associations levels, anemia, among pregnant women. Reproductive history gathered through a questionnaire. Body mass index (BMI) calculated/computed women's weight height. Linear binary regression analyses were performed. total 334 women enrolled. median...
Neonatal infections including sepsis and urinary tract are considered among the leading causes of mortality in neonatal intensive care units (NICU). Thus, use empiric antibiotics is very important infected neonates success this practice mainly reliant on availability an up-to-date antibiogram for currently used antibiotic drugs. In study, we aim to determine bacteriological profile susceptibility pattern bacteria isolated from blood or/and urine cultures belonging patients at NICU. A total...
Plant-derived compounds are renowned for their remarkable pharmacological properties, holding immense promise therapeutic interventions in human health. In this study, we aimed to assess the antimicrobial, anti-hemolytic, antioxidant, and wound healing attributes of watercress oil incorporated into Vaseline gel (OLG) compared alone. OLG was formulated through a meticulous process involving addition under agitation conditions. High-performance liquid chromatography analysis unveiled rich...
The failure to treat infectious diseases due the continual emergence of drug-resistant microbes poses a huge and serious challenge for human health globally. Currently, discovery development natural therapeutic compounds are attracting considerable attention from researchers worldwide. In this project, two types pollen grains (maize clover) were evaluated potential antimicrobial activities. Extracts both purified using HPLC, which has been shown have numerous phenolic flavonoid compounds....
Background: Aurones are a sub-set of the flavone family that possess number biological activities, including anti-cancer, anti-inflammatory, anti-microbial, anti-parasitic and anti-viral. Due to their high availability, simple synthesis, generally low toxicity, aurones could be attractive candidates for safer cancer drugs. This study aims evaluate anti-proliferation anti-metastasis activity series synthesized aurone derivatives. Keywords: Aurones, benzofuranone, selectivity, apoptosis, cell motility.
Persimmon (Diospyros kaki L.) leaves are popular as a tea infusion in Asia and their main active ingredients flavonoids. The present study aimed to explore the anticancer properties of flavonoids isolated from persimmon (PLF).We investigated vitro anti-proliferative activity PLF against several human cancer cell lines. Apoptosis intracellular reactive oxygen species (ROS) induced by were accessed using high-content analysis with florescent staining. ability scavenge free radicals was...
Background:The oligostilbenes cis-and trans-gnetin H were previously studied for their ability to inhibit cancer cell proliferation and induce apoptosis.However, an in-depth understanding of the proteins involved in this process remains poorly understood.Methods: The act as antioxidant by scavenging one stable free radicals DPPH was tested.We also tested both compounds generate oxidative stress through elevating reactive oxygen species (ROS) resulting apoptosis using lung line A549.Also,...