A5042594044- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Global Maternal and Child Health
- Cerebral Palsy and Movement Disorders
- Prenatal Screening and Diagnostics
- Infant Development and Preterm Care
- Neonatal and fetal brain pathology
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- COVID-19 Impact on Reproduction
- Preterm Birth and Chorioamnionitis
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy-related medical research
- Child Nutrition and Water Access
- Gestational Diabetes Research and Management
- Global Health Workforce Issues
- Reproductive Health and Contraception
- Trauma and Emergency Care Studies
- Family and Disability Support Research
- Congenital Diaphragmatic Hernia Studies
- Folate and B Vitamins Research
- Neuroscience of respiration and sleep
- Global Health and Surgery
- Neonatal and Maternal Infections
- Respiratory viral infections research
Dalhousie University
2016-2025
World Health Organization
2025
Izaak Walton Killam Health Centre
2002-2024
Women's and Children's Health Network
2008-2024
McMaster University
2024
University of Ottawa
2001-2024
Edwards (United Kingdom)
2024
St. Michael's Hospital
2024
St Michaels Hospital
2024
Public Health Agency of Canada
2024
The extent to which birth defects after infertility treatment may be explained by underlying parental factors is uncertain.We linked a census of with assisted reproductive technology in South Australia registry births and terminations gestation period at least 20 weeks or weight 400 g registries (including cerebral palsy for any gestational period). We compared risks (diagnosed before child's fifth birthday) among pregnancies women who received technology, spontaneous (i.e., without...
In Brief OBJECTIVE: To determine if the rates of pregnancy complications, preterm birth, small for gestational age, perinatal mortality, and serious neonatal morbidity are higher among mothers aged 35–39 years or 40 older, compared with 20–24 years. METHODS: We performed a population-based study all women in Nova Scotia, Canada, who delivered singleton fetus between 1988 2002 (N = 157,445). Family income 1995 was obtained through confidential linkage tax records (n 76,300). The primary...
There are limited high-quality, population-level data about the effect of SARS-CoV-2 infection on pregnancy using contemporaneous comparator cohorts.To describe maternal and perinatal outcomes associated with in to assess variables severe disease pregnant population.CANCOVID-Preg is an observational surveillance program for SARS-CoV-2-affected pregnancies Canada. This analysis presents exploratory, from 6 Canadian provinces period March 1, 2020, October 31, 2021. A total 6012 persons a...
OBJECTIVES. It is unclear whether declines in neonatal and infant mortality have led to changes the occurrence of cerebral palsy. We conducted a study examine investigate recent temporal prevalence palsy population-based cohort very preterm infants who were 24 30 weeks gestational age. METHODS. A born between January 1, 1993, December 31, 2002, was evaluated by Perinatal Follow-up Program Nova Scotia. extended age 2 years ascertain presence or absence for overall survival. Infant survival...
The aim of this study was to establish the outcome very severe birth asphyxia in a group babies intensively resuscitated at birth. 48 infants, born between 1966 and 1971 inclusive, were selected; 15 apparently stillborn 33 had not established spontaneous respirations by 20 minutes after One-half them died, but 3 7 years later three-quarters survivors are normal. Later handicap associated with factors leading prolonged partial intrapartum asphyxia, while acute periods more complete...
To briefly outline the strengths and limitations of cerebral palsy (CP) registers, to report on findings Australian Cerebral Palsy Register (ACPR) pertaining a population cohort children with CP.De-identified data were extracted from ACPR for people CP in birth years 1993 2006, South Australia, Victoria, Western Australia. Live prevalence was estimated risk factors described.The overall (including those whose postneonatally acquired) 2006 2.1 per 1000 live births (95% confidence interval...
Davies, Michael J.*†‡; Moore, Vivienne M.*†§; Willson, Kristyn J.*†§; Van Essen, Phillipa∥; Priest, Kevin¶; Scott, Heather∥; Haan, Eric A.‡∥#; Chan, Annabelle∥¶ Author Information
<h3>Background:</h3> Operative vaginal delivery (OVD) is considered safe if carried out by trained personnel. However, opportunities for training in OVD have declined and, given these shifts practice, the safety of unknown. We estimated incidence rates trauma following Canada, and quantified variation instrument, region, level obstetric care institutional volume. <h3>Methods:</h3> conducted a cohort study all singleton, term deliveries Canada between April 2013 March 2019, excluding Quebec....
<h3>Background:</h3> Hypertensive disorders of pregnancy (HDP) are a leading cause severe maternal morbidity (SMM). We sought to explore trends in HDP and related outcomes Canada. <h3>Methods:</h3> In this retrospective population-based study, we used hospital discharge data from Canada, excluding Quebec, identify females who had an diagnosis during birth admission between 2012 2021. analyzed temporal geographical HDP, as well adverse associated with HDP. <h3>Results:</h3> Among 2 804 473...
Abstract Background There is no international consensus on the definition and components of severe maternal morbidity (SMM). Objectives To propose a comprehensive SMM, to create an empirically justified list SMM types subtypes, use this examine in Canada. Methods Severe was defined as set heterogeneous conditions known be associated with illness prolonged hospitalisation or high case fatality. Candidate types/subtypes were evaluated using information all hospital deliveries Canada (excluding...
The COVID-19 pandemic posed a unique set of risks to pregnant women and people. SARS-CoV-2 infection in pregnancy is associated with increased risk severe illness adverse perinatal outcomes. However, evidence regarding the use vaccines shows safety efficacy. Despite eligibility recommendations for vaccination among people Canada, uptake remains lower compared general population, warranting exploration influencing factors. COVERED study, national prospective cohort, utilized web-based surveys...
Accumulating evidence has linked the use of assisted reproductive techniques (ARTs) with increased risk birth defects. Both in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are associated A proportion excess defects after IVF or ICSI may result from patient characteristics related to infertility. The extent contribution parental factors is unknown. It also unknown whether similar ICSI. aim this study was compare among pregnancies women who conceived ART those had...
This study sought to quantify temporal trends and provincial territorial variations in severe maternal morbidity (SMM) Canada.The used data on all hospital deliveries Canada (excluding Québec) from 2003 2016 examine 2012 regional variations. SMM was identified using diagnosis intervention codes. Contrasts among periods regions were quantified rate ratios (RRs) 95% confidence intervals (CIs). Temporal changes also assessed chi-square tests for trend (Canadian Task Force Classification...
The purpose of this study was to determine the prevalence, clinical characteristics, prenatal diagnosis and occurrence other birth defects with abdominal wall in births terminations pregnancy South Australia (SA) Western (WA) over period 1980–90. Cases gastroschisis, exomphalos, bladder exstrophy, cloacal exstrophy body stalk anomaly were ascertained from WA Birth Defects Registry (1980–90) SA Register (1986–90). registers are comparable population‐based data collections information on...
Several studies have documented changes in the rates preterm birth and stillbirth during COVID-19 pandemic. We carried out a study to examine obstetric intervention, birth, Canada from March August 2020.The included all singleton hospital deliveries (excluding Québec) 2020 (and for years 2015-2019) with information obtained Canadian Institute Health Information. Data Ontario were examined separately because this province had highest of population. Rates odds ratios 95% confidence intervals...
To estimate the incidence and factors associated with combined vaginal-cesarean delivery in twin pregnancies.We studied all births weighing 500 g or more during a 20-year period (1980-1999) at tertiary care center. Major anomalies, monoamniotic conjoined twins, antepartum fetal deaths were excluded.During this period, 105,987 women delivered, of whom 1565 (1.5%) had twins. Of these, 1151 sets fulfilled study criteria. The mode was vaginal 653 (56.8%), cesarean 448 (38.9%), 50 (4.3%). During...
To review evidence for the increased incidence of late diagnosed developmental dysplasia hip (DDH) in South Australia; to identify perinatal risk factors associated with DDH babies born between 2003 and 2009 SA.Linkage study data collected prospectively by Australian Birth Defects Register (SABDR) Pregnancy Outcome Statistics Unit (SA Department Health), supplemented medical records review.All children 2003-2009 whom was 3 months 5 years age notified SABDR (data inclusion range, 2003-2014)....
Aim: Cytokine polymorphisms may alter the fetal inflammatory response, increasing susceptibility to cerebral palsy (CP). This study investigates associations between selected mediator and cytokine gene (Toll‐like receptor‐4 (TLR‐4) Asp299Gly, interleukin‐6 G‐174C interleukin‐4 C‐589T) CP from 443 infants 883 control infants. Results were correlated with viral nucleic acids in same samples. Results: At all gestational ages (GA), TLR‐4 was associated a decreased risk of developing...
Maternal death surveillance in Canada relies on hospitalization data, which lacks information the underlying cause of death. We developed a method for identifying causes maternal death, and quantified frequency by cause.