A5016576073- Immune Response and Inflammation
- Immune cells in cancer
- Aquaculture disease management and microbiota
- Immune Cell Function and Interaction
- Invertebrate Immune Response Mechanisms
- Immunotherapy and Immune Responses
- Adipokines, Inflammation, and Metabolic Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Antimicrobial Peptides and Activities
- Glycosylation and Glycoproteins Research
- Inhalation and Respiratory Drug Delivery
- Tuberculosis Research and Epidemiology
- Helicobacter pylori-related gastroenterology studies
- Cancer Research and Treatments
- Cytokine Signaling Pathways and Interactions
- Cancer, Hypoxia, and Metabolism
- Pediatric health and respiratory diseases
- Gut microbiota and health
- Probiotics and Fermented Foods
- Angiogenesis and VEGF in Cancer
- RNA Interference and Gene Delivery
- Transgenic Plants and Applications
- Escherichia coli research studies
- Fatty Acid Research and Health
- Natural Antidiabetic Agents Studies
Niigata University of Pharmacy and Medical and Life Sciences
2016-2025
Photonics Electronics Technology Research Association
2017-2025
National Cancer Center Hospital East
2025
Kagawa University
2010-2018
National Fisheries University
2004-2016
Tokushima Bunri University
2001-2009
Tokyo University of Science
2004-2009
Takano Hospital
1997-2000
The University of Tokyo
1997-1998
Teikyo University Hospital
1992
Objectives To examine (1) the effects of trauma on changes in neutrophil L-selectin and CD11b expression levels soluble (2) whether these alterations are different leukocyte subpopulations those patients who develop multiple organ dysfunction syndrome. Materials Methods Twenty with Injury Severity Score (ISS) >or=to 16 15 ISS score < were studied. Arterial blood collected serially after injury. The staining surface adhesion molecules was performed antibodies against CD11b. Positive cell...
Lipopolysaccharide (LPS), an endotoxin, induces systemic inflammation by injection and is thought to be a causative agent of chronic inflammatory diseases, including type 2 diabetes mellitus (T2DM). However, our previous studies found that oral LPS administration does not exacerbate T2DM conditions in KK/Ay mice, which the opposite response from injection. Therefore, this study aims confirm aggravate investigate possible mechanisms. In study, mice with were orally administered (1 mg/kg...
TPS605 Background: Carbonic Anhydrase (CA)IX is a type of carbonic anhydrase and expected to be useful target for detecting tumors with poor prognosis. Particularly in clear cell renal carcinoma, high CAIX expression has been reported large proportion patients. In this study, we developed novel radioligand agent called PD-32766 that specifically binds administered it recurrent cases carcinoma (ccRCC) patient. Safety, imaging, pharmacokinetics dosimetry are evaluated. Methods: Between May...
The pathogenesis of Alzheimer's disease (AD) remains unclear, but an imbalance between the production and clearance amyloid-β (Aβ) peptides is known to play a critical role in AD progression. A promising preventative approach enhance normal Aβ activity brain phagocytes such as microglia. In mice, intraperitoneal injection Toll-like receptor 4 agonist was shown exhibit effect on AD-related pathology. Our previous clinical study demonstrated that orally administered Pantoea agglomerans-derived...
We cloned two cDNAs denoted as RT-LBP/BPI-1 and RT-LBP/BPI-2, respectively, which were derived from the mRNA of head kidney rainbow trout. They showed structural homology with LPS-binding protein (LBP) bactericidal/permeability-increasing (BPI) in mammals. The full-length cDNA RT-LBP/BPI-2 is 1666 1741 bp, respectively. Both encoded 473 aa residues, including amino acids conserved mammalian LBP BPI proteins that assumed to be involved LPS binding. overall coding sequence has 33% acid human...