Background Data has emerged on possible beneficial effects of probiotics in respiratory tract viral infections, but it is unclear if the promising positive evidenced are due to a reduced load during infections. The aims this work were investigate effect peroral probiotic Lactobacillus rhamnosus GG (American Type Culture Collection [ATCC], Accession No. 53103) consumption human rhinovirus (HRV) nasopharyngeal lavage samples experimental HRV infection, and correlate clinical symptoms. Methods...

Abstract Background In recent years, enhanced recovery after surgery (ERAS) guidelines have been developed to optimize pre-, intra-, and postoperative care of surgical oncology patients. The aim this study was compare management outcome patients undergoing head neck cancer (HNC ) with free flap reconstruction at our institution before the implementation ERAS guidelines. Methods This retrospective comprised 283 HNC between 2013 2020. Patients operated protocol in October 2017 formed pre-ERAS...

Objectives To evaluate the incidence and nature of complications associated with diagnostic interventional sialendoscopies to report intervention failures in a prospective setup. Study Design Prospective observational study. Setting Academic tertiary care university hospital. Subjects Methods Patients who underwent or sialendoscopy between October 2015 December 2016 were prospectively enrolled. Patient data, operation‐related factors, treatment failures, recorded into database analyzed....

Conclusion: Lactobacillus rhamnosus GG (L.GG) was present in all adenoids of children receiving the L. product. However, since L.GG also found from placebo group, one cannot confirm its effect on occurrence rhinovirus (RV) or enterovirus (EV). Objectives: The study conducted to determine whether a 3-week oral consumption would lead presence probiotic adenoid tissue. Furthermore, nasopharyngeal RV and EV findings symptom data were investigated. Method: tissue samples collected 40 aged 1–5...

Abstract Purpose To identify complications of surgical tracheostomies in otorhinolaryngologic patients and adjust our processes to be properly prepared the future. Methods We reviewed retrospectively all ( n = 255) performed by otolaryngologist-head neck surgeons at Helsinki University Hospital between Jan 2014 Feb 2017. Patient demographics, details, medical complications, tracheostomy-related mortality were recorded from hospital charts. Risk factors for assessed. Results Altogether, 55...

Background: Various detection methods to identify the primary in head and neck cancer of unknown (HN-CUP) require evaluation improve standardize management.Objectives: To evaluate use different diagnostic methods, which aim at decreasing incidence HN-CUP.Material methods: We conducted a retrospective analysis patients with HN-CUP Helsinki University Hospital during 1995–2011. evaluated clinical assessment, definitive treatment, histopathology, follow up. analyzed success identifying site...

Abstract Background The majority of new oropharyngeal squamous cell carcinoma (OPSCC) cases are associated with human papillomavirus and favorable prognosis. Post‐treatment follow‐up should be targeted to patients at greatest risk for disease recurrence. Methods To assess the benefits routine clinical surveillance in OPSCC, we reviewed all visits conducted 2014 Helsinki University Hospital Department Otorhinolaryngology. Results Of 366 visits, 26 (7%) were from presenting a symptom,...

Primary treatment of papillary thyroid carcinoma (PTC) with lateral lymph node metastasis is surgery, but the extent neck dissection remains undefined. Preoperative imaging used to guide although its sensitivity and specificity for defining number level affected nodes on relatively modest. Our aim was assess role preoperative magnetic resonance (MRI) in predicting requisite levels patients regionally metastatic PTC, a focus Levels II V. All PTC who had undergone at Department...

To review indications, patient characteristics, frequency, and safety for surgical tracheostomies performed by otolaryngologist-head neck surgeons in a single tertiary care center. Surgical at Helsinki University Hospital between January 2014 February 2017 were retrospectively reviewed. Patient demographics, data, peri- postoperative mortality information collected from the hospital charts. Minimum follow-up was 18 months. The total population 255, with majority (n = 181; 71%) of males....

In acute epiglottitis (AE) or supraglottitis (AS), the management of airway is crucial. We hypothesized that tracheotomized patients recover faster than intubated do. retrospectively reviewed all adult AE and AS patients, who underwent intubation tracheotomy between 2007 2018 in a tertiary care center. Patient demographics, treatment, complications were analyzed. The cohort comprised 42 patients. was secured with 50% 50%. All (n = 21) three treated intensive unit (p < 0.0001)....

To investigate clinical and radiological factors predicting worse outcome after (chemo)radiotherapy ([C]RT) in oropharyngeal squamous cell carcinoma (OPSCC) with a focus on apparent diffusion coefficient (ADC). This retrospective study included 67 OPSCC patients, treated (C)RT curative intent diagnosed during 2013-2017. Human papilloma virus (HPV) association was detected p16 immunohistochemistry. Of all tumors, 55 were positive, 9 negative, 3 the status unknown. Median follow-up time 38...

The association of the surgical approach, specialty, and other factors with outcomes treatment Zenker diverticulum (ZD) have been debated in literature.

Abstract Purpose Laryngeal fracture is a rare but potentially life-threatening trauma. Fractures vary from mild to dislocated and extensive with risk of severe complications. This study investigated the occurrence, clinical characteristics management laryngeal fractures in last 15 years. Material methods A retrospective population-based cohort reviewing all at Helsinki University Hospital 2005–2019. Patient records imaging studies were systematically reviewed for mode injury, type, secondary...

Although needle biopsy is widely used in work-up of lymphadenopathy, lymph node excision (LNE) often required especially lymphoma diagnostics. LNE an invasive procedure, which carries a potential risk complications. However, comprehensive studies evaluating the spectrum and occurrence complications are lacking.This study addresses role preoperative biopsies patients who underwent LNE. Furthermore, surgical related to analyzed.Altogether 321 patients, two-year period 2018-19, fulfilled our...

Evidence on the risk of second primary cancer (SPC) following laryngeal squamous cell carcinoma (LSCC) is limited, especially in Europe.Patients diagnosed with LSCC from 1953-2018 were retrieved Finnish Cancer Registry. A total 6241 patients identified adding to 49,393 person-years (PY) follow-up until end 2019. Only one patient emigrated and was lost follow-up. Both standardized incidence ratios (SIR) excess absolute (EAR) per 1000 at (PYR) calculated relative general population....

Retrospective, questionnaire survey.