A5086821225- Optical Imaging and Spectroscopy Techniques
- Non-Invasive Vital Sign Monitoring
- Heart Rate Variability and Autonomic Control
- Spectroscopy and Chemometric Analyses
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Stroke Rehabilitation and Recovery
- Mental Health Research Topics
- Digital Mental Health Interventions
- Peripheral Artery Disease Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Musculoskeletal pain and rehabilitation
- Noise Effects and Management
- Water Quality Monitoring and Analysis
- Phonocardiography and Auscultation Techniques
- Transcranial Magnetic Stimulation Studies
- Muscle activation and electromyography studies
- Skin and Cellular Biology Research
- Folate and B Vitamins Research
- Drug Transport and Resistance Mechanisms
- Inflammatory Myopathies and Dermatomyositis
- Visual perception and processing mechanisms
- Liver Disease Diagnosis and Treatment
- Tactile and Sensory Interactions
Oldenburger Institut für Informatik
2023-2025
RWTH Aachen University
2023-2025
Carl von Ossietzky Universität Oldenburg
2018-2024
Universitätsklinikum Aachen
2023
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
2022
University of Tübingen
2022
Abstract Compared to functional magnetic resonance imaging (fMRI), near infrared spectroscopy (fNIRS) has several advantages that make it particularly interesting for neurofeedback (NFB). A pre-requisite NFB applications is with fNIRS, signals from the brain region of interest can be measured. This study focused on supplementary motor area (SMA). Healthy older participants (N = 16) completed separate continuous-wave (CW-) fNIRS and (f)MRI sessions. Data were collected executed imagined hand...
The expansion of functional near-infrared spectroscopy (fNIRS) methodology and analysis tools gives rise to various design analytical decisions that researchers have make. Several recent efforts developed guidelines for preprocessing, analyzing, reporting practices. For the planning stage fNIRS studies, similar guidance is desirable. Study preregistration helps transparently document study protocols before conducting study, including materials, methods, analyses, thus, others verify,...
The optical brain imaging method functional near-infrared spectroscopy (fNIRS) is a promising tool for real-time applications such as neurofeedback and brain-computer interfaces. Its combination of spatial specificity mobility makes it particularly attractive clinical use, both at the bedside in patients' homes. Despite these advantages, optimizing fNIRS use requires careful attention to two key aspects: ensuring good maintaining high signal quality. While detects superficial cortical...
Researchers using functional near infrared spectroscopy (fNIRS) are increasingly aware of the problem that conventional filtering methods do not eliminate systemic noise at frequencies overlapping with task frequency. This is a when signals averaged for analysis, even more so single trial data used as in online neurofeedback or BCI applications where insufficiently preprocessed means feeding back instead brain activity looking brain-behavior relationships on trial-by-trial basis. For...
Functional near-infrared spectroscopy (fNIRS) is a promising tool for neurofeedback (NFB) or brain-computer interfaces (BCIs). However, fNIRS signals are typically highly contaminated by systemic activity (SA) artifacts, and, if not properly corrected, NFB BCIs run the risk of being based on noise instead brain activity. This can likely be reduced correcting SA, in particular when short-distance channels (SDCs) available. Literature comparing correction methods with and without SDCs still...
A shared understanding of terminology is essential for clear scientific communication and minimizing misconceptions. This particularly challenging in rapidly expanding, interdisciplinary domains that utilize functional near-infrared spectroscopy (fNIRS), where researchers come from diverse backgrounds apply their expertise fields such as engineering, neuroscience, psychology. The fNIRS Glossary Project was established to develop a community-sourced glossary covering key terms, including...
The hepatic Na+-taurocholate cotransporting polypeptide NTCP/SLC10A1 is important for the uptake of bile salts and selected drugs. Its inhibition results in increased systemic salt concentrations. NTCP also entry receptor hepatitis B/D virus. We investigated interindividual SLC10A1/NTCP expression using various omics technologies. mRNA expression/protein abundance was quantified well-characterized 143 human livers by real-time PCR LC-MS/MS-based targeted proteomics. Genome-wide SNP arrays...
Neurofeedback allows individuals to monitor and self-regulate their brain activity, potentially improving human function. Beyond the traditional electrophysiological approach using primarily electroencephalography, haemodynamics measured with functional magnetic resonance imaging (fMRI) more recently, near-infrared spectroscopy (fNIRS) have been used (haemodynamic-based neurofeedback), particularly improve spatial specificity of neurofeedback. Over recent years, especially fNIRS has...
In neuroimaging research, efforts to enhance replication and reproducibility have increased the focus on improving transparency, particularly in complex data analysis processes. We conducted a multi-lab collaborative study involving 38 international teams that analyzed two functional Near-Infrared Spectroscopy (fNIRS) datasets. These tested seven group-level forty individual-level hypotheses, they submitted detailed reports their pipelines testing outcomes. The results showed significant...
Significance A shared understanding of terminology is essential for clear scientific communication and minimizing misconceptions. This particularly challenging in rapidly expanding, interdisciplinary domains that utilize functional near-infrared spectroscopy (fNIRS), where researchers come from diverse backgrounds apply their expertise fields such as engineering, neuroscience, psychology. Aim The fNIRS Glossary Project was established to develop a community-sourced glossary covering key...
Introduction In acute ischemic stroke, progressive impairment of cerebral autoregulation (CA) is frequent and associated with unfavorable outcomes. Easy assessment blood flow CA in stroke units bedside tools like near-infrared spectroscopy (NIRS) might improve early detection deterioration. This study aimed to assess dynamic multichannel CW-NIRS (AIS) patients compared agematched healthy controls. Methods reaction was amplified by changes head bed position. Long- short channels were used...
Major Depressive Disorder (MDD) has a significant impact on the daily lives of those affected. This concept paper presents project that aims at addressing MDD challenges through innovative therapy systems. The consists two use cases: multimodal neurofeedback (NFB) and an AI-based virtual assistant (VTA). NFB integrates EEG fNIRS to comprehensively assess brain function. goal is develop open-source toolbox for EEG-fNIRS integration, augmented by VTA optimized efficacy. will be able collect...
The optical brain imaging method functional near-infrared spectroscopy (fNIRS) is a promising tool for real-time applications such as neurofeedback and brain-computer interfaces. Its combination of spatial specificity mobility makes it particularly attractive clinical use, both at the bedside in patients’ homes. Despite these advantages, optimizing fNIRS use requires careful attention to two key aspects: ensuring good maintaining high signal quality. While detects superficial cortical...
Abstract Significance Functional near-infrared spectroscopy (fNIRS) is a promising tool for neurofeedback (NFB) or brain–computer interfaces (BCIs). However, fNIRS signals are typically highly contaminated by systemic activity (SA) artifacts, and, if not properly corrected, NFB BCIs run the risk of being based on noise instead brain activity. This can likely be reduced correcting SA, in particular when short-distance channels (SDCs) available. Literature comparing correction methods with and...
<title>Abstract</title> In occupational medicine, monitoring individual stress-related physiological responses is an effective tool for minimizing health risks at the workplace. From audiology perspective, this particularly concerns effects of auditory stress, which leads to increased listening effort with subsequent hearing fatigue. A study was conducted investigate whether cardio-respiratory can detect a multi-level combination physical and stressors. To their measurability determine...
Parkinson's disease (PD) is commonly treated with pharmacological or physical therapies, which are often associated side effects. Combining motor imagery (MI) neurofeedback (NFB) offers a potential complementary non-pharmacological therapy. The aim of this study was to develop and evaluate functional near-infrared spectroscopy (fNIRS)-guided NFB protocol that integrates MI whole-body movements changes in deoxygenated hemoglobin concentration (d[HbR]) alleviate symptoms PD.Three groups (N =...
In neuroimaging research, efforts to enhance replication and reproducibility have increased the focus on improving transparency, particularly in complex data analysis processes. We conducted a multi-lab collaborative study involving 38 international teams that analyzed two functional Near-Infrared Spectroscopy (fNIRS) datasets. These tested seven group-level forty individual-level hypotheses, they submitted detailed reports their pipelines testing outcomes. The results showed significant...
The temporal properties of visual selective attention change with age as reflected in a longer and deeper impairment identifying the second two targets rapid stream distracters. In younger adults, identification rates for both can be improved by simultaneous, task irrelevant sound. Research response time tasks has shown that older participants benefit more from bimodal stimulation than subjects. Here we examine whether this facilitation also found setting which relevant items need to...