A5081523515- Optical Imaging and Spectroscopy Techniques
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Neural and Behavioral Psychology Studies
- Photoacoustic and Ultrasonic Imaging
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Neonatal and fetal brain pathology
- Hemodynamic Monitoring and Therapy
- Visual perception and processing mechanisms
- Face Recognition and Perception
- Spectroscopy Techniques in Biomedical and Chemical Research
- Heart Rate Variability and Autonomic Control
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Motor Control and Adaptation
- Evolutionary Psychology and Human Behavior
- Diabetes Management and Research
- Analog and Mixed-Signal Circuit Design
- Musculoskeletal pain and rehabilitation
- Cognitive and developmental aspects of mathematical skills
- Stroke Rehabilitation and Recovery
- Infant Nutrition and Health
- Balance, Gait, and Falls Prevention
- Facial Nerve Paralysis Treatment and Research
- Neonatal Respiratory Health Research
University of Padua
2016-2025
Institute of Developmental Physiology
2020
University College London
2015-2019
University of Trento
2017
Rosie Hospital
2016
In recent years, it has been demonstrated that using functional near-infrared spectroscopy (fNIRS) channels with short separations to explicitly sample extra-cerebral tissues can provide a significant improvement in the accuracy and reliability of fNIRS measurements. The aim these short-separation is measure same superficial hemodynamics observed by standard while also being insensitive brain. We use Monte Carlo simulations photon transport anatomically informed multilayer models determine...
Despite motion artifacts are a major source of noise in fNIRS infant data, how to approach correction this population has only recently started be investigated. Homer2 offers wide range methods and previous work on simulated adult data suggested the use Spline interpolation Wavelet filtering as optimal for recovery trials affected by motion. However, differ from those adults' both amplitude frequency occurrence. Therefore, artifact recommendations derived might not data. We hypothesized that...
This report is the second part of a comprehensive two-part series aimed at reviewing an extensive and diverse toolkit novel methods to explore brain health function. While first focused on neurophotonic tools mostly applicable animal studies, here, we highlight optical spectroscopy imaging relevant noninvasive human studies. We outline current state-of-the-art technologies software advances, most recent impact these neuroscience clinical applications, identify areas where innovation needed,...
Abstract Functional near infrared spectroscopy and electroencephalography are non-invasive techniques that rely on sensors placed over the scalp. The spatial localization of measured brain activity requires precise individuation sensor positions and, when individual anatomical information is not available, accurate registration these to a head atlas. Both issues could be successfully addressed using photogrammetry-based method. In this study we demonstrate can accurately detected from video...
Seizures in the newborn brain represent a major challenge to neonatal medicine. Neonatal seizures are poorly classified, under-diagnosed, difficult treat and associated with poor neurodevelopmental outcome. Video-EEG is current gold-standard approach for seizure detection monitoring. Interpreting EEG requires expertise impact of on developing remains understood. In this case study we present first ever images haemodynamic human infant brain, obtained using simultaneous diffuse optical...
The position of each source and detector "optode" on the scalp, their relative separations, determines sensitivity functional near-infrared spectroscopy (fNIRS) channel to underlying cortex. As a result, selecting appropriate scalp locations for available sources detectors is critical every fNIRS experiment. At present, it standard practice user undertake this task manually; select what they believe are best place optodes so as sample given cortical region-of-interest (ROI). This process...
Functional near-infrared spectroscopy (fNIRS) is a non-invasive vascular-based functional neuroimaging technology that can assess, simultaneously from multiple cortical areas, concentration changes in oxygenated-deoxygenated hemoglobin at the level of microcirculation blood vessels. fNIRS, with its high degree ecological validity and very limited requirement physical constraints to subjects, could represent valid tool for monitoring responses research field neuroergonomics. In virtual...
Motion artifacts are a notorious challenge in the functional near-infrared spectroscopy (fNIRS) field. However, little is known about how to deal with them resting-state data.
Tracking the connectivity of developing brain from infancy through childhood is an area increasing research interest, and fNIRS provides ideal method for studying infant as it compact, safe robust to motion. However, data analysis methods are still underdeveloped compared those available fMRI. Dynamic causal modelling (DCM) advanced technique developed fMRI data, that aims estimate coupling between regions how this might be modulated by changes in experimental conditions. DCM has recently...
The ability to produce high-quality images of human brain function in any environment and during unconstrained movement the subject has long been a goal neuroimaging research. Diffuse optical tomography, which uses intensity back-scattered near-infrared light from multiple source-detector pairs image changes haemoglobin concentrations brain, is uniquely placed achieve this goal. Here, we describe new generation modular, fibre-less, high-density diffuse tomography technology that provides...
Objective. In the last few years, interest in applying virtual reality systems for neurorehabilitation is increasing. Their compatibility with neuroimaging techniques, such as functional near-infrared spectroscopy (fNIRS), allows investigation of brain reorganization multimodal stimulation and real-time control changes occurring activity. The present study was aimed at testing a novel semi-immersive visuo-motor task (VMT), which has features being adopted field upper limb motor function....
ABSTRACT When humans move both hands simultaneously, bimanual coupling or interference can occur. The circles‐lines paradigm is used to study the and effects: Participants simultaneously draw either lines circles with (congruent), one hand other (incongruent condition). Despite extensive behavioral research on this paradigm, our knowledge of neural circuitry involved remains limited. Here, we capitalized advantages provided by functional near‐infrared spectroscopy unveil substrates within an...
Here, we studied posture and movement coordination adopted by expert climbers. The investigation of such expertise might be particular interest to gain understanding about the mechanisms underlying biomechanical control vertical quadrupedal locomotion. A novel custom setup was developed analyze motion center-of-mass (COM) complementary information dynamic distribution reaction forces under feet during climbing in nine elite climbers (EC) subjects. Two adaptive features were found EC. First,...
The present study was aimed at describing a semi-immersive virtual reality environment, driven by 3D hand sensing device (LEAP Motion Controller), to define task based on ball moving path. prefrontal cortex haemodynamic responses during the execution of this demanding were evaluated 16-channel functional near-infrared spectroscopy (fNIRS) system. A bilateral ventrolateral activation found task. Although proposed has not been yet applied in neuro-rehabilitation field, it potential be adopted...
In diffuse optical tomography (DOT), overlapping and multidistance measurements are required to reconstruct depth-resolved images of oxy- ([Formula: see text]) deoxy- (HHb) hemoglobin concentration changes occurring in the brain. These can be considered an indirect measure brain activity, under assumption intact neurovascular coupling. Broadband systems also allow redox state cytochrome c oxidase (oxCCO) measured, which important biomarker when coupling is impaired. We used DOT [Formula:...
Abstract A consolidated practice in cognitive neuroscience is to explore the properties of human visual working memory through analysis electromagnetic signals using cued change detection tasks. Under these conditions, EEG/MEG activity increments posterior parietal cortex scaling with number memoranda are often reported hemisphere contralateral objects' position array. This highly replicable finding clashes several failures observe compatible hemodynamic modulations fMRI or fNIRS comparable...