A5068050568- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Nosocomial Infections in ICU
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Rabies epidemiology and control
- Venomous Animal Envenomation and Studies
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- COVID-19 diagnosis using AI
- COVID-19 epidemiological studies
- Patient Satisfaction in Healthcare
- Zoonotic diseases and public health
- Cardiac tumors and thrombi
- Mycobacterium research and diagnosis
- Antimicrobial Resistance in Staphylococcus
- Vascular Procedures and Complications
- Streptococcal Infections and Treatments
- COVID-19 and Mental Health
- Antibiotic Resistance in Bacteria
- COVID-19 Pandemic Impacts
- Central Venous Catheters and Hemodialysis
- Viral Infections and Vectors
- Computational Drug Discovery Methods
Institute of Human Virology
2025
University of Abuja Teaching Hospital
2012-2024
University of Abuja
2016-2023
Iran University of Medical Sciences
2023
University of Nigeria
2023
Nigerian Institute of Medical Research
2022-2023
University of Sharjah
2023
Aminu Kano Teaching Hospital
2014-2020
Bayero University Kano
2015-2018
Abstract Background As part of the Global Action Plan against antimicrobial resistance (AMR), countries are required to generate local evidence inform context-specific implementation national action plans AMR (NAPAR). We aimed evaluate knowledge, attitude, and practice (KAP) regarding antibiotic prescriptions (APR) among physicians in tertiary hospitals Nigeria, determine predictors KAP APR AMR. Methods In this cross-sectional study, we enrolled practicing from all six geopolitical zones...
With reports of surges in COVID-19 case numbers across over 50 countries, country-level epidemiological analysis is required to inform context-appropriate response strategies for containment and mitigation the outbreak. We aimed compare features first second waves Nigeria.We conducted a retrospective Surveillance Outbreak Response Management Analysis System data waves, which were between 27 February 24 October 2020, 25 2020 3 April 2021, respectively. Descriptive statistical measures...
Snakebite envenoming is a major cause of morbidity and mortality in rural areas the tropics. Timely administration effective antivenom remains mainstay management.The study was quantitative descriptive aimed at exploring causes effects delay, distance time taken to access care on snakebite outcomes Nigeria. All prospective victims reporting Kaltungo General Hospital were enrolled. Data demography, date bitten, admitted, site bite, circumstances snakebite, responsible snake, clinical...
Snakebite envenoming is a major public health problem throughout the rural tropics. Antivenom effective in reducing mortality and remains mainstay of therapy. This study aimed to determine cost-effectiveness using antivenoms for Nigeria.Economic analysis was conducted from healthcare system perspective. Estimates model inputs were obtained literature. Incremental Cost Effectiveness Ratios (ICERs) quantified as deaths Disability-Adjusted-Life-Years (DALY) averted antivenom A decision analytic...
The COVID-19 pandemic has had a great toll on global health. Frontline healthcare workers (FHCW) directly involved in the treatment of patients have faced some physical and psychological challenges. This study explored stigma traumatic experiences FHCW during Nigeria.We recruited twenty through purposive snowball sampling techniques. Face-to-face in-depth interviews were conducted for all participants, qualitative analysis data was done using Colaizzi's phenomenological method.Five themes...
Snakebite though neglected, affects 5 million people yearly. More neglected is the psychological effect of envenomation. We determined prevalence and pattern depression among patients admitted into snakebite wards Kaltungo General Hospital Nigeria, percentage recognized by clinicians. also assessed for factors associated with depression.In a descriptive hospital based study, we used Patient Health questionnaire (PHQ-9) to make diagnosis patients. reviewed patients' clinical records determine...
Hospital-acquired infections (HAI) are a global problem and major public health concern in hospitals throughout the world. Quantification of HAI is needed developing countries; hence we describe results 2-year surveillance data tertiary hospital Nigeria.This study review using secondary collected at referral center northwestern Nigeria. The was forms modeled based on Centre for Disease Control (CDC) protocol. Descriptive statistics were used to present as frequencies percentages.518 patients...
Hospital-acquired infections (HAIs) are an important cause of morbidity and mortality. This study examined the epidemiology, clinical outcomes microbiological profile HAIs. prospective was carried out on patients identified to have developed HAIs while admitted medical wards, surgical dialysis unit intensive care (ICU) hospital. Patients were recruited consecutively until target population reached. A evaluation relevant laboratory investigations out. total 100 who had 144 episodes studied....
COVID-19 mortality rate has not been formally assessed in Nigeria. Thus, we aimed to address this gap and identify associated risk factors during the first second waves This was a retrospective analysis of national surveillance data from all 37 States Nigeria between February 27, 2020, April 3, 2021. The outcome variable amongst persons who tested positive for SARS-CoV-2 by Reverse-Transcriptase Polymerase Chain Reaction. Incidence rates calculated dividing number deaths total person-time...
Several efforts to repurpose drugs for COVID-19 treatment have largely either failed identify a suitable agent or agents identified did not translate clinical use. Reasons that been suggested explain the failures include use of inappropriate doses, are clinically achievable, in screening experiments, and pre-clinical laboratory surrogates predict efficacy. In this study, we used an innovative algorithm, incorporates dissemination implementation considerations, potential using iterative...
Abstract Background Infections are the leading cause of hospitalization and mortality in transplant recipients. Nigeria has a growing number renal The aim this study was to determine pattern infections allograft recipients one major centers Nigeria. Methods All case records on follow‐up were retrieved. Those that had infection at any time after transplantation selected. Demographic clinical information collected analyzed. Results Thirty‐three analyzed, out which 24/33 (72.7%) males, with...
Tuberculosis (TB) is a serious disease of public health concern, mainly in low- and middle-income countries. Most these countries have challenges diagnosis treatment TB people with smear-negative pulmonary tuberculosis (SNPTB), which remains significant challenge because the global burden disease. We evaluated epidemiology clinical presentation SNPTB cohort patients high HIV burden. The study was cross-sectional among four major hospitals that care for TB/HIV north-central Nigeria. All 18...
Abstract Introduction: The COVID-19 pandemic has had a great toll on global health. Frontline healthcare workers (FHCW) directly involved in the treatment of patients have faced some physical and psychological challenges. This study explored stigma traumatic experiences FHCW during Nigeria. Methods: We recruited twenty through purposive snowball sampling techniques. Face-to-face in-depth interviews were conducted for all participants, qualitative analysis data was done using Colaizzi's...
Cardiac myxoma is a benign (non-malignant) neoplasm that represents the most common primary tumour of heart. We present case 36 year old woman with background hypertension who presented features left ventricular failure and seizures, was found during transthoracic echocardiography to have atrial protruding through mitral valve orifice. She subsequently had excision myxoma. The usefulness early in any patient presenting heart even when aetiology seems obvious cannot be over-emphasised.
Presentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients complicated outcomes, foetal loss and live premature delivery at 5 7 months gestation, respectively, maternal loss, were diagnosed pulmonary TB. Chest radiography computed tomography showed widespread reticuloalveolar infiltrates consolidation cavitations, respectively. Both Human Immunodeficiency Virus (HIV) seronegative sputum smear negative for Sputum GeneXpert MTB/Rif (Xpert MTB/RIF)...
Background Although tremendous success has been achieved in the development and deployment of effective COVID-19 vaccines, developing therapeutics for treatment those who do come down with disease limited success. To repurpose existing drugs COVID-19, we previously showed, qualitatively, that erythromycin, retapamulin, pyridoxine, folic acid, ivermectin inhibit SARS-COV-2-induced cytopathic effect (CPE) Vero cells. Aim This study aimed to quantitatively explore inhibition SARS-CoV-2-induced...
Abstract Background There are challenges in the diagnosis of TB people with smear-negative pulmonary (SNPTB) resource-limited settings. We evaluated diagnostic usefulness Xpert MTB/RIF compared culture among SNPTB. Methods The study was a cross-sectional patients tests and sputum (using Lowenstein-Jensen medium) were performed. Sensitivity specificity calculated. Results Of 150 studied, sensitivity GeneXpert 81.8 97.4%, respectively. Conclusion assay comparative SNPTB patients.
globally, the ravaging effect of coronavirus disease-2019 (COVID-19), pandemic is evident on public health and global economy. We aimed at describing clinical characteristic management outcome COVID-19 patients in Abuja, Nigeria.we conducted a retrospective study by reviewing hospital charts first 200 admitted isolation center, University Abuja Teaching Hospital (UATH), Gwagwalada. Extracted data includes; demographic data, symptoms, underlying comorbidities, outcomes. The interest was...
Background: Nigeria has a sizable population of Fulani pastoralists. Zoonotic infections like Bovine tuberculosis [TB] are common among Nomadic (NF) and their livestock. Close interaction between the nomads animals provide critical human-animal interface with potential for transmission zoonoses. We conducted survey to determine prevalence primary infection cattle in Kano, north-Western Nigeria. Methods & Materials: performed TST all inhabitants nomadic setting randomly selected cattle....