A5015078723- Viral Infections and Immunology Research
- Animal Disease Management and Epidemiology
- Animal Virus Infections Studies
- Microbial infections and disease research
- Chinese history and philosophy
- China's Ethnic Minorities and Relations
- Traffic control and management
- RNA and protein synthesis mechanisms
- Aquaculture disease management and microbiota
- Respiratory viral infections research
- Immune Response and Inflammation
- Evolution and Science Education
- Autonomous Vehicle Technology and Safety
- Biosensors and Analytical Detection
- Animal Genetics and Reproduction
- Mitochondrial Function and Pathology
- CRISPR and Genetic Engineering
- Viral Infections and Vectors
- Plant-Microbe Interactions and Immunity
- Metabolism and Genetic Disorders
- Photosynthetic Processes and Mechanisms
- Vehicle Dynamics and Control Systems
- Tea Polyphenols and Effects
- Virology and Viral Diseases
- Fungal Plant Pathogen Control
Harbin Medical University
2024
State Administration of Traditional Chinese Medicine of the People's Republic of China
2021-2024
Air Force Medical University
2021-2024
Hebei Normal University of Science and Technology
2024
Craft Group (China)
2023
Weifang University
2003-2022
Shanghai University of Electric Power
2020
Hefei University of Technology
2018-2019
Sichuan University
2019
State Key Laboratory of Hydraulics and Mountain River Engineering
2019
Plant pathogens, such as bacteria, fungi, oomycetes and nematodes, rely on wide range of virulent effectors delivered into host cells to suppress plant immunity. Although phytobacterial have been intensively investigated, little is known about the function plant-parasitic Globodera pallida, a cyst nematode responsible for vast losses in potato tomato industries. Here, we demonstrate using vivo vitro ubiquitination assays (Globodera pallida) effector RHA1B an E3 ubiquitin ligase that employs...
Gray mold, caused by the fungus Botrytis cinerea, is most significant postharvest disease of kiwifruit. In present study, iTRAQ with LC-ESI-MS/MS was used to identify kiwifruit proteins associated response B. cinerea. A total 2,487 in were identified. Among them, 292 represented differentially accumulated (DAPs), 196 DAPs having increased, and 96 decreased accumulation cinerea-inoculated vs. water-inoculated, control kiwifruits. penetration site reorganization, cell wall degradation, MAPK...
Haemophilus parasuis is classified mainly through serotyping, but traditional serotyping always yields non-typable (NT) strains and unreliable results via cross-reactions. Here, we surveyed the serotype prevalence of Chinese H. isolates using (gel immuno-diffusion test, GID) molecular (multiplex PCR, mPCR). We also investigated why discrepant between these methods were obtained, mPCR failure whole-genome sequencing. Of 100 isolate tested, 73 (73%) 93 (93%) serotyped by GID test mPCR,...
Abstract A reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) assay was rapidly used to detect serotype Asia 1 of foot-and-mouth disease virus (FMDV) within 45 min at 61°C. All FMDV reference strains were positive by RT-LAMP, while other viruses such as serotypes O, C, and classical swine fever virus, vesicular porcine reproductive respiratory syndrome Japanese encephalitis remained negative. Furthermore, sreotype samples able RT-LAMP assay. This may be suitable...
Mycoplasma bovis is a major bovine pathogen that causes considerable economic losses in the cattle industry worldwide. Moreover, M. biofilm can persist environment and its host. To date, antigens recognized by convalescent sera their comparison with planktonic cells have not yet been explored. This study utilized an immunoproteomic approach using two-dimensional electrophoresis, immunoblotting serum, subsequent matrix-assisted laser desorption/ionization time-of-flight tandem mass...
Myocardial ischemia-reperfusion injury (MI/RI) is associated with increased oxidative damage and mitochondrial dysfunction, resulting in an elevated risk of mortality. MI/RI may be alleviated by protecting cardiomyocytes from stress. Lutein, which belongs to a class carotenoids, has proven effective cardiovascular disease treatment due its remarkable antioxidant properties, but application limited poor stability low bioavailability vivo.
Sirtuin 6 (SIRT6) is an NAD+-dependent deacetylase with a significant role in 20% of all cancers, such as colon cancers and rectal adenocarcinoma. However, there currently no effective drug for related to SIRT6. To explore potential inhibitors SIRT6, it essential reveal details the interaction mechanisms between SIRT6 at atomic level. The nature small molecules from herbs have many advantages inhibitors. Based on conformational characteristics inhibitor Compound 9 (Asinex ID: BAS13555470),...
Haemophilus parasuis infection is of considerable economic importance in the swine industry due to high costs associated with treatment and loss animals all over world. In present study, loop-mediated isothermal amplification (LAMP) described for rapid specific detection this species. A primer set derived from inf B gene H. was used validate assay using 15 reference strains, 39 clinical isolates, 75 positive samples, 18 other pathogens. The results indicated that reactions were confirmed...
A short linear peptide was designed according to the antigenic site analysis of VP1 protein foot-and-mouth virus (FMDV) serotype O and synthesized as immunogen. The peptide, which covers region from amino acid 133 160 FMDV, linked N-terminal cysteine conjugated with carrier keyhole limpet hemocyanin (KLH). Normal 6- 8-week-old BALB/c mice were immunized 20 μg dose antigen four times. splenocytes fused SP2/0 mouse myeloma cells, positive hybridomas selected by indirect enzyme-linked...
Aiming at traditional control methods are not suitable for solving the multiconstraint problem of vehicle steering and lane-change maneuvering process, a hybrid optimization scheme based on dynamic adaptive salp swarm algorithm Gaussian pseudospectral method (DASSA-GPM) is proposed its strong global search capability. Based inverse dynamics model, lane change motion planning converted into an optimal which then nonlinear programming by applying group solved through sequential quadratic (SQP)...
In order to accelerate national industrial upgrading of transportation and deepen the development logistics industry, it is imperative construct land-sea channel between Shandong Liaoning provinces. Taking practical situations two places into account, paper aims investigate application M N mode in process cargo roll on-roll off, drop pull transport then elaborate site selection issue centers from perspective P-median model. Meanwhile, proposes adopt “south bridging-north rolling” concept...