Joaquim Soares da Costa Júnior

ORCID: 0000-0002-9849-201X
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About
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Research Areas
  • Phytochemistry Medicinal Plant Applications
  • Essential Oils and Antimicrobial Activity
  • Natural Compound Pharmacology Studies
  • Phytochemicals and Antioxidant Activities
  • Agricultural and Food Sciences
  • Carcinogens and Genotoxicity Assessment
  • Natural product bioactivities and synthesis
  • Synthesis of Organic Compounds
  • Chemistry and Chemical Engineering
  • Bee Products Chemical Analysis
  • Business and Management Studies
  • Phytochemical compounds biological activities
  • Phytochemistry and Bioactive Compounds
  • Phytochemicals and Medicinal Plants
  • Horticultural and Viticultural Research
  • Plant tissue culture and regeneration
  • Solar-Powered Water Purification Methods
  • Polysaccharides Composition and Applications
  • Soil Management and Crop Yield
  • Garlic and Onion Studies
  • Rural Development and Agriculture
  • Medicinal Plants and Neuroprotection
  • Herbal Medicine Research Studies
  • Food Science and Nutritional Studies
  • Growth and nutrition in plants

Instituto Federal do Piauí
2010-2023

Universidade Federal do Rio Grande do Norte
2020

Bellingham Technical College
2015

Universidade Luterana do Brasil
2011

Universidade Federal do Piauí
1999-2007

On-line a 20 de julho 2020Os cistos teratóides são hamartomas, que contém tecidos derivados do endoderma, mesoderma e ectoderma, relativamente raros na cavidade oral, onde frequentemente encontrados região da linha média assoalho bucal.Este estudo relata um caso cisto teratoide assintomático, localizado em sublingual,

10.24873/j.rpemd.2020.07.697 article PT cc-by-nc-nd Revista Portuguesa de Estomatologia Medicina Dentária e Cirurgia Maxilofacial 2020-07-16

Combretum leprosum Mart. (Combretaceae), a shrub popularly known as mofumbo, is used in folk medicine for treatment of uterine bleeding, pertussis, gastric pain, and sedative. The aim this study was to (1) determine the phytochemical profile,(2) identify chemical constituents (3) examine antioxidant cytogenotoxic activity ethanolic extracts fractions stem bark leaves. plant material (leaf bark) submitted extraction with ethanol, followed by partition using hexane, chloroform, ethyl acetate....

10.1080/15287394.2021.1875345 article EN Journal of Toxicology and Environmental Health 2021-01-25

Phytochemical profile, antioxidant potential, total phenolic content and cytogenotoxic effect (Allium cepa test) were assessed in hexane (HE), ethyl acetate (EA) methanol (ME) extracts of Jatropha mollissima leaves. analysis revealed the presence triterpenes HE, which also observed conjunction with flavonoids EA. Saponins, catechins, phenols, tannins, flavonoids, flavones, flavonols xanthones present ME. The highest activity, determined by DPPH free radical scavenging ABTS assay, phenol...

10.1016/j.sajb.2019.02.007 article EN cc-by South African Journal of Botany 2019-02-25

The Indoor positioning systems have gained significant attention in recent decades, and currently remain a challenging task, given the inherent characteristics of indoor environments. In this paper, novel approach to resolving problem is proposed through development an extension method naive Bayesian classifier, known as dynamic classifier. exhibited better performance than algorithms used for comparison with average error 0.92 m.

10.55905/oelv23n1-174 article EN cc-by-nc OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA 2025-01-23

Garcinielliptone FC (GFC) isolated from hexanic fraction seed extract of species Platonia insignis Mart. It is widely used in folk medicine to treat skin diseases both humans and animals as well the decoction has been diarrheas inflammatory diseases. However, there no research on GFC effects central nervous system rodents. The present study aimed evaluate at doses 25, 50 or 75 mg/kg seizure parameters determine their anticonvulsant activity its amino acid (γ-aminobutyric (GABA), glutamine,...

10.1016/j.pbb.2014.05.021 article EN publisher-specific-oa Pharmacology Biochemistry and Behavior 2014-06-06

Poincianella bracteosa has been widely used in folk medicine to treat catarrhal infections, diarrhea, and anemia; however, phytochemical toxicogenetic data are still lacking. The objective of this study was examine the antioxidant characteristics as well assess cytogenotoxicity antigenotoxicity hexane (HF), ether (EF) ethyl acetate (AF) fractions P. leaves using Allium cepa bioassay. Phytochemical analysis revealed presence saponins phenolic groups. EF fraction contained a higher content...

10.1080/15287394.2020.1824136 article EN Journal of Toxicology and Environmental Health 2020-09-30

Flavorings used in cookies, electronic cigarettes, popcorn, and breads contain approximately 30 chemical compounds, which makes it difficult to determine correlate signs symptoms of acute, subacute or chronic toxicity. The aim this study was characterize a butter flavoring chemically subsequently examine the vitro vivo toxicological profile using cellular techniques, invertebrates, lab mammals. For first time, ethyl butanoate found as main compound (97.75%) 24 h-toxicity assay employing...

10.1080/15287394.2023.2172502 article EN Journal of Toxicology and Environmental Health 2023-02-15

Context: Platonia insignis Mart. (Clusiaceae), commonly known as "bacuri," is a timber and fruit native species of the Brazilian Amazon. Some plants Clusiaceae family have their pharmacological properties associated with presence xanthone polycyclic polyprenylated acylphloroglucinols derivatives, which antioxidant anticarcinogenic activities.

10.3109/13880209.2011.611146 article EN Pharmaceutical Biology 2011-12-01

Commercialization of Mauritia flexuosa (buriti) fruits in Brazil is at an early stage. Herein, we evaluate the nutritional value pulp, peel and endocarp samples from buriti fruits, perform macroscopic microscopic evaluations analyze their physicochemical properties. Size mass, pH, sugar protein contents, soluble/insoluble fiber, total titratable acidity energy were analyzed. Mineral profiling was performed by dispersive X-ray fluorescence spectrometry, fatty acids phytosterols determined gas...

10.17113/ftb.60.02.22.7106 article EN cc-by Food Technology and Biotechnology 2022-03-29

The objective of present study was to evaluate the antioxidant and anticonvulsant activities dichloromethane fraction (DMF) from Platonia insignis Mart., Clusiaceae. DMF P. (2 mg/kg) tested by intraperitoneal (i.p.) effects on lipid peroxidation level, nitrite formation, as well locomotor activities. Wistar rats were treated with, (saline/Tween 80 0.5%, i.p., control group), mg/kg, pilocarpine (400 P400 or combination i.p.) plus P400). After treatments all groups observed for 24 h. In group...

10.1590/s0102-695x2011005000163 article EN cc-by-nc-nd Revista Brasileira de Farmacognosia 2011-09-08

ABSTRACTHeliotropium elongatum is used to treat inflammation, cough, and flu. This study aimed characterize the phytochemical profile determine total phenolic content (TPC), antioxidant cytogenotoxic activity of ethanolic extract (EE), fractions H. leaves. In analysis, organic acids, reducing sugars, flavonoids, saponins, anthraquinones, steroids/triterpenes, depsides/depsidones were detected in EE and/or (hexanic/FH, chloroformic/FC, ethyl acetate/FAE, hydromethanolic/FHM). The highest TPC...

10.1080/15287394.2023.2254815 article EN Journal of Toxicology and Environmental Health 2023-09-08

Introdução: O processo de cicatrização é uma sequência reações para reconstituir o tecido. bacurizeiro (Platonia insignis Mart.) nativo da Amazônia e usado como cicatrizante antibiótico. Objetivo: Analisar a feridas cutâneas tratadas com banha bacuri. Metodologia: Utilizaram-se 46 ratos Wistar, machos. Confeccionou-se ferida 2 cm diâmetro no dorso dos animais em seguida foram distribuídos dois grupos: controle tratado Foram avaliados 4º, 7º 14º dias do pós-operatório. Resultados: A...

10.5585/conssaude.v9i4.2357 article PT ConScientiae Saúde 2010-12-30

Poincianella bracteosa (Tul.) L.P. Queiroz. (Fabaceae), known as catingueira, is traditionally used in medicine to treat catarrhal infections, diarrhea, hepatitis and anemia. However, there are no studies on toxicogenetics effects of P. bracteosa. The present study aimed investigate the phytochemical profile well mutagenic antimutagenic potential aqueous barks extract Allium cepa Mus musculus. Barks from were collected Teresina (PI, Brazil) male Swiss mice (Mus musculus) provided by vivarium...

10.15517/rbt.v67i6.33883 article EN cc-by Revista de Biología Tropical 2019-11-04

CHEMICAL CONSTITUENTS OF Philodendrom imbe Schott.The chemical composition of the ethanolic extract leaves and roots from Philodendron Schott was investigated.The main constituents isolated were β-sitosterol one polyprenoid hexaprenol, 6β-hydroxy-stigmast-4-en-3-one, a steroid, not yet reported in gender.A mixture constituents, namely, ethyl myristoleate, α-bisabolol, isopalmitate, 3-octadecenyl-phenol major component palmitate, roots.Structure elucidation these secondary metabolites...

10.1590/s0100-40422007000100009 article EN cc-by-nc Química Nova 2007-02-01

Platonia insignis Mart. is a vegetable of the Clusiaceae Lindl., family that popularly known as “bacuri” in Brazil. It widely used folk medicine to treat human diarrheas and inflammatory diseases. has antiparasitic activity, antioxidant, anticarcinogenic action, addition vasorelaxant potential. The present study investigates leishmanicidal, cytotoxic genotoxic activities different biological systems, well chemical constituents hexane extract from P. seeds. analysis non-volatile was analyzed...

10.33448/rsd-v11i2.25504 article EN Research Society and Development 2022-01-21

In this work, a metabolic profile of Mansoa hirsuta was investigated, and in vitro assays theoretical approaches were carried out to evaluate its antioxidant potential. The phytochemical screening detected saponins, organic acids, phenols, tannins, flavonoids, alkaloids extracts leaves, branches, roots. Through LC-MS analysis, the triterpenes oleanolic acid (m/z 455 [M-H]-) ursolic identified as main bioactive components. roots revealed moderate potential DPPH test all more active ABTS test....

10.3390/molecules27186016 article EN cc-by Molecules 2022-09-15

In this study, secondary metabolites, toxicology and antioxidant properties of chloroform fractions from leaves (FCFMh), branches (FCGMh), roots (FCRMh) Mansoa hirsuta were investigated. The phytochemical screening detected flavonoids, especially chalcones. Through Liquid chromatography with mass spectrometry—LC–MS analysis, the flavonoids (isoorientin-2″-O-arabinoside), triterpenes (oleanolic acid ursolic acid) ceramide (phytosphingosine) identified. From Artemia salina assay, fraction...

10.3390/biophysica3030028 article EN cc-by Biophysica 2023-06-28

Terminalia actinophylla (Mart), commonly known as "chapada", is used in folk medicine for the treatment of diarrhea, diabetes and anti-inflammatory. However, studies on its toxicity are still incipient. The present work was carried out with objective evaluating phytochemical profile cytogenotoxic effect ethanolic extract T. bark using Allium cepa L. seed. Seeds A. were subjected to different concentrations (1.25, 2.5, 5 10 mg/mL), a negative control (NC - distilled water) well trifluralin...

10.33448/rsd-v9i9.7322 article EN Research Society and Development 2020-08-21

The major constituent from the hexane extract of seeds P. insignis is GFC (garcinielliptone FC).Doses 25, 50 and 75 mg/kg were aseptically suspended in 0.05% Tween 80 dissolved 0.9% saline (vehicle) orally administered for 30, 90 120 consecutive days to adult Swiss mice.In this work, repeated oral administration, animals both sexes, demonstrates that compound not able induce mortality and/or behavioral changes addition, body weight gain, feed intake disposal excreta altered by administration...

10.17265/2328-2150/2015.07.002 article EN cc-by-nc Journal of Pharmacy and Pharmacology 2015-07-28

A hipertensão arterial é fator de morbimortalidade no mundo, por isso necessário explorar outras formas tratamento mais acessíveis e que possibilitem um efetivo bloqueio do mecanismo fisiopatológico envolvido. Assim, o presente trabalho tem como objetivo principal avaliar os parâmetros farmacocinéticos metabolização in silico para moléculas derivadas triazolonas bis-triazolonas inibidoras da enzima conversora angiotensina (ECA). Os foram analisados meio utilização programa PreADMET....

10.5753/sbcas.2021.16085 article PT 2021-06-15
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