A5002223377- Phytochemistry Medicinal Plant Applications
- Neuroscience and Neuropharmacology Research
- Phytochemistry and Biological Activities
- Cholinesterase and Neurodegenerative Diseases
- Agricultural and Food Sciences
- Essential Oils and Antimicrobial Activity
- Plant-Derived Bioactive Compounds
- Medicinal Plant Extracts Effects
- Natural Compound Pharmacology Studies
- Pharmacological Effects of Natural Compounds
- Pharmacology and Obesity Treatment
- Medicinal Plants and Neuroprotection
- Pharmacogenetics and Drug Metabolism
- Helminth infection and control
- Synthesis of Organic Compounds
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemistry and biological activity of medicinal plants
- Plant Toxicity and Pharmacological Properties
- Biochemical Analysis and Sensing Techniques
- Natural product bioactivities and synthesis
- Chemical synthesis and alkaloids
- Neurotransmitter Receptor Influence on Behavior
- Phytochemicals and Antioxidant Activities
- Olfactory and Sensory Function Studies
- Phytochemical compounds biological activities
Universidade Federal do Piauí
2012-2023
Instituto Federal do Piauí
2011
The objective of the present study was to evaluate antinociceptive effects phytol using chemical and thermal models nociception in mice assess its antioxidant vitro. Phytol administered intraperitoneally (i.p.) at doses 25, 50, 100, 200 mg/kg. In acetic acid-induced writhing test, significantly reduced number contortions compared control group (P < 0.001). formalin amount time spent paw licking both phases (the neurogenic inflammatory phases), this effect being more pronounced second phase...
Phytol, a branched chain unsaturated alcohol, is particularly interesting because it an isolated compound from essential oils of different medicinal plants. The aim this study was to evaluate the anxiolytic-like effects phytol in animal models clarify their possible action mechanism. After acute intraperitoneal treatment with at doses 25, 50 and 75 mg/kg behavioral open-field, elevated-plus-maze, rota-rod, light–dark, marble-burying pentobarbital sleeping time tests were utilized. In open...
The present study evaluated anxiolytic activity of (+)-limonene epoxide (EL), through the marble burying test (MBT) assay, and antioxidant potential in vitro vivo mice hippocampus adult subjected to experimental anxiety protocol. For behavioral studies, analyses, were treated orally with 0.05% Tween 80 dissolved 0.9% saline solution (vehicle), ascorbic acid 250 mg/kg, diazepam (2 mg/kg) EL (25, 50 75 mg/kg). Results suggest an effect epoxide. A reduction number buried marbles groups doses...
The antioxidant and antinociceptive activities of Citrus limon essential oil (EO) were assessed in mice or vitro tests. EO possesses a strong potential according to the scavenging assays. Moreover, it presented scavenger activity against all Orally, (50, 100, 150 mg/kg) significantly reduced number writhes, and, at highest doses, paw licks. Whereas naloxone antagonized action (highest doses), this suggested, least, participation opioid system. Further studies currently progress will enable...
Studies showing anxiolytic-like properties of natural products have grown. This paper evaluated if carvacryl acetate (CA) could be studied as an alternative drug to treat anxiety disorders. Elevated plus maze (EPM) tests , light-dark box (LDB) tests, and marble-burying (MBTs) were performed on mice. In the first protocol, activities CA 25, 50, 75 100mg/kg at single doses compared those vehicle, buspirone 5mg/kg (BUSP) diazepam 1mg/kg (DZP). second actions tested for GABAergic serotonergic...
Garcinielliptone FC (GFC), a natural prenylated benzophenone, was extracted from Platonia insignis Mart. (Clusiaceae), native plant commonly known as bacuri and used in traditional Brazilian medicine for the treatment of skin diseases. The aim this study to evaluate cytotoxic leishmanicidal effects GFC using vitro models. experimental data demonstrated that polyisoprenylated benzophenone possesses activities.
Epileptic syndromes are highly prevalent neurological conditions and can often be disabling. In order to find an alternative for treatment, this study evaluated anticonvulsant effects of carvacryl acetate (CA), a derivative monoterpene carvacrol, after seizures induced by pilocarpine (P400), picrotoxin (PIC) or pentylenetetrazol (PTZ). We also analyzed the CA on Na+, K+-ATPase δ-aminolevulinic acid dehydratase (δ-ALA-D) activities in hippocampus mice P400, PIC PTZ. addition, glutamate,...
Mauritia flexuosa L., traditionally known as “buriti”, exhibits chemoprotective properties including antioxidant, antithrombotic, and nutritional actions. The aim of this study was to examine the oral anti-inflammatory activity epicarp, mesocarp endocarp obtained from M. fruits using in vivo models verify physiological benefits. anti-edematogenic action determined phlogistic agents induce paw edema peritonitis. Pro-inflammatory cytokines, cell migration peritoneal cells, histological...
Context: Platonia insignis Mart. (Clusiaceae), commonly known as "bacuri," is a timber and fruit native species of the Brazilian Amazon. Some plants Clusiaceae family have their pharmacological properties associated with presence xanthone polycyclic polyprenylated acylphloroglucinols derivatives, which antioxidant anticarcinogenic activities.
not respond well to conventional treatments.Thus, iso-6-spectaline (SPEC) may possess a modulatory role in the treatment of neurodegenerative diseases, since their piperidine alkaloid compound can interrupt cellular oxidative processes CNS.The effects SPEC on CNS have yet been determined, therefore, would be important conduct these studies clarify its brain action mechanism.Piperidine alkaloids are abundant nature and many them known exhibit some biological activity.In our search for...
A experimentação tornou-se uma abordagem fundamental no ensino de química, por proporcionar melhor compreensão do conteúdo, bem como visão aperfeiçoada da ciência. Neste contexto, este trabalho teve objetivo apresentar a alunos 2º ano médio em Redenção Gurguéia Piauí, Brasil, o uso atividades experimentais com materiais baixo custo meio videoaulas, propiciando experiência inovadora e agregadora processo ensino-aprendizagem, tempos pandemia Covid-19. Para tanto, foi necessário analisar...