A5076755267- Hormonal Regulation and Hypertension
- Diabetes Treatment and Management
- Diabetes Management and Research
- Adrenal Hormones and Disorders
- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Pharmacology and Obesity Treatment
- Metabolism, Diabetes, and Cancer
- Sexual Differentiation and Disorders
- Bacterial Infections and Vaccines
- Adrenal and Paraganglionic Tumors
- Adipokines, Inflammation, and Metabolic Diseases
- Hormonal and reproductive studies
- Apelin-related biomedical research
- Potassium and Related Disorders
- Colorectal Cancer Treatments and Studies
- Biochemical Analysis and Sensing Techniques
- HER2/EGFR in Cancer Research
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Neonatal and Maternal Infections
- Diet and metabolism studies
- Cancer Treatment and Pharmacology
- Regulation of Appetite and Obesity
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Pancreatic function and diabetes
First Hospital of Shanxi Medical University
2020-2025
Shanxi Medical University
2020-2025
Shandong University
2014
Abstract: Uric acid (UA) is the end product of purine metabolism in human, and imbalance between production excretion results disturbance serum uric (SUA). There evidence suggesting that pituitary-target gland hormones can affect UA through regulating activity xanthine oxidase transporters. Related endocrine diseases including thyroid dysfunction, polycystic ovary syndrome, acromegaly Cushing’s syndrome are often accompanied by elevated levels. In addition to direct influence abnormal...
BACKGROUND Autonomous cortisol secretion (ACS) is linked to a higher prevalence of metabolic abnormalities and an increased risk major adverse cardiovascular events. AIM To evaluate glucose bone metabolism in patients with ACS using continuous monitoring system (CGMS) dual-energy X-ray absorptiometry (DXA). METHODS Patients diagnosed ACS, including Cushing syndrome, mild (MACS), nonfunctional adrenal incidentaloma (NFAI), were recruited for this study. Glucose variability glycemic status...
To investigate the post-treatment effect of dorzagliatin in drug-naïve patients with type 2 diabetes (T2D) regarding achievement stable glycaemic control and drug-free remission.Patients who completed treatment SEED trial achieved were enrolled this 52-week study without any antidiabetic medication. The primary endpoint was remission probability at week 52 using Kaplan-Meier method. potential factors that contribute to based on characteristics before after analysed. A post hoc sensitivity...
Background: This study aimed to investigate the characteristics and extent of glycometabolism impairment in patients with adrenal diseases, including Cushing syndrome, primary aldosteronism, pheochromocytoma, nonfunctional incidentaloma. Methods: case-control enrolled thirty-two diseases as disease groups eight healthy individuals controls. Blood glucose levels were indicated by concentration interstitial fluid, which was documented using flash monitoring system. According system data,...
Purpose: Liraglutide, a type of glucagon-like peptide-1 receptor agonist, has significant anti-hyperglycaemic activity without increasing the incidence hypoglycaemia. In addition, it can improve β-cell function and insulin resistance. The flash glucose monitoring system (FGMS) is novel method to document consecutive detailed interstitial levels, further reflecting blood levels. This study aimed investigate therapeutic effect liraglutide on management (glucose variability, hyperglycaemia,...
Here, we report a case of patient with symptoms Cushing syndrome, who is diagnosed primary generalized glucocorticoid hypersensitivity in the end. The patient's relevant laboratory tests and imaging examinations are described. Mifepristone, receptor antagonist, was prescribed its therapeutic effect on electrolyte level, lipid metabolism, bone metabolism observed during treatment. endocrine assessment indicated normal pituitary-adrenal axis regulation function but reduced cortisol secretion....
Commonly used glucocorticoids replacement regimens in patients with hypopituitarism have difficulty mimicking physiological cortisol rhythms and are usually accompanied by risks of over-treatment, adverse effects on glucose metabolism. Disorders associated metabolism established risk factors cardiovascular events, one the life-threatening ramifications.To investigate glycometabolism profile receiving prednisone (Pred) replacement, to clarify impacts different Pred doses consequent...
Purpose: This study aimed to investigate the glycometabolism, fat mass, and lean mass in primary aldosteronism (PA) during disease progression. Patients Methods: diagnosed with PA healthy controls (HCs) were enrolled. A flash glucose monitoring system (FGMS) dual-energy X-ray absorptiometry (DEXA) used measure variability target rate along mass. Comparative analysis of FGMS- or DEXA-derived parameters correlation analyses between these progression performed. Results: Increased poor rate, an...
Coexistence of congenital adrenal hyperplasia due to 21-hydroxylase deficiency, Graves' disease and 47, XXX is rare. We report a case 25-year-old woman presented with masculine appearance, hirsutism enlarged clitoris. Lab tests showed elevated serum 17 hydroxyprogesterone, testosterone, dehydroepiandrosterone. Gene test revealed heterozygous gene mutation in CYP21A2:NM_000500:exon4:c.518 T > A, NM_000500:exon8:c.C1024T. Karyotype analysis XXX. After prednisone replacement antithyroid...
Abstract Background Congenital adrenal hyperplasia (CAH) with 17α-hydroxylase deficiency is a rare disease; patients often require lifetime cortisol treatment. In this case report, we presented patient CAH and deficiency, who was previously misdiagnosed as having primary aldosteronism. Furthermore, the flash glucose monitoring system (FGMS) used to ascertain suitable therapeutic regimen for patient. Case presentation A 29-year-old woman sex dysgenesis, hypertension hypokalaemia. She had been...
BACKGROUND Multiple studies demonstrate that fluctuating blood glucose level produces greater damage compared with sustained hyperglycemia. Flash monitoring system is an effective method in documenting variability, contributing to better management and reduced hypoglycemic event occurrence. AIM To investigate the improvement glycemic variability (GV), level, metabolic indexes of patients type 2 diabetes mellitus after combined treatment exenatide once weekly (EXQW) metformin. METHODS...