A5100672463- Tryptophan and brain disorders
- Lipid metabolism and disorders
- Heat shock proteins research
- Bipolar Disorder and Treatment
- vaccines and immunoinformatics approaches
- Nuclear Physics and Applications
- Monoclonal and Polyclonal Antibodies Research
- Microscopic Colitis
- Prion Diseases and Protein Misfolding
- RNA Interference and Gene Delivery
- Adenosine and Purinergic Signaling
- Genomics, phytochemicals, and oxidative stress
- Atherosclerosis and Cardiovascular Diseases
- Kruppel-like factors research
- Trace Elements in Health
- Apelin-related biomedical research
- Industrial Gas Emission Control
- Biosimilars and Bioanalytical Methods
- Medicinal Plants and Neuroprotection
- Neurological diseases and metabolism
- Neurological Disease Mechanisms and Treatments
- Astro and Planetary Science
- Advanced NMR Techniques and Applications
- Bone Metabolism and Diseases
- Advanced Biosensing Techniques and Applications
Shanghai Tenth People's Hospital
2023
Tongji University
2023
Chinese Academy of Sciences
2012-2023
Fuzhou University
2023
Institute of Urban Environment
2023
University of Nottingham Ningbo China
2023
Shaanxi University of Chinese Medicine
2023
Harbin Medical University
2022
First Affiliated Hospital of Harbin Medical University
2022
Shandong University of Traditional Chinese Medicine
2021
Abstract Identifying the exact epitope positions for a monoclonal antibody (mAb) is of critical importance yet highly challenging to Ab design biomedical research. Based on previous versions SEPPA 3.0, we present SEPPA-mAb above purpose with high accuracy and low false positive rate (FPR), suitable both experimental modelled structures. In practice, appended fingerprints-based patch model considering structural physic-chemical complementarity between possible complementarity-determining...
Lily Bulb and Rehmannia Decoction (LBRD), is a traditional Chinese formula that has been shown to be safe effective against depression; however, its material basis pharmacological mechanisms remain unknown.
The emission of volatile organic compounds (VOCs) has resulted in increasingly severe harm to the environment and human health. In recent years, biological methods have become preferred technology for VOC removal due their environmental friendliness economic advantages. Based on theory bibliometrics, this study analyzed research articles reviews published Web Science Core Collection (WOSCC) database from 1966 2021. knowledge map visualization software CiteSpace was utilized analyze progress...
Gastric and colorectal cancers have a major impact on public health, are the most common malignant tumors in China. The aim of this research was to study whether polymorphisms CHCHD3P1-HSP90AB7P, GRID1, HSPA12A, PRLHR, SBF2, POLD3 C11orf93-C11orf92 genes associated with risk gastric Chinese Han population.We genotyped seven single nucleotide (SNPs) from genes. We selected 588 patients cancer 449 cancer, along 703 healthy controls. All these SNPs were evaluated using χ² test genetic model...
Background: A large number of studies have shown a close relationship between ADORA2A and the pathological mechanism schizophrenia. However, to our knowledge, there has been no examining association gene schizophrenia in Chinese Han population. Purpose: The objective this study was examine adenosine A2A receptor ( ) single nucleotide polymorphisms North Patients methods: We detected (SNPs) using polymerase chain reaction-restriction fragment length polymorphism analyses summarized results...
Heat shock protein 90 (HSP90), functions as a molecular chaperone in biosynthesis play an important role signal transduction, immune responses and embryogenesis. However, the function research of HSP90 invertebrates is limited. To further understand mechanism stress response, we have isolated fragment homologue from mud crab Scylla paramamosain through transcriptome sequencing mixture hepatopancreas hemocytes, The full-length cDNA harvested RACE technology it contains 73 bp 5’terminal UTR,...
Abstract Background and purpose Human prion diseases (PrDs) are a group of fatal transmissible neurodegenerative disorders that diagnosed definitively in post mortem brains. Calmodulin (CaM) is ubiquitous calcium‐binding protein. Increased brain CaM level has been reported prion‐infected rodent models some scrapie‐infected cells. However, the putative alteration cerebrospinal fluid (CSF) human PrDs uncertain. Here, we try to figure out profiles CSF sporadic Creutzfeldt‐Jacob disease. Methods...
Abstract: Topiramate has been used increasingly in the management of psychiatric conditions. Clinical trials demonstrated that topiramate augmentation was effective controlling negative symptoms schizophrenia. This case report presents a 38-year-old man with schizophrenia who achieved full symptom remission upon adjunctive use topiramate. However, remarkable finding this is concomitant decrease level prolactin when (50 mg/day) started and rebound after discontinuation Previous studies stated...
To observe the effect of electroacupuncture (EA) on ferroptosis and apoptosis-related proteins in substantia nigra midbrain mice with Parkinson's disease (PD), so as to explore its possible mechanisms treatment PD.Twenty-four C57BL/6 were randomly divided into blank, model EA groups, 8 each group. The PD was established by continuous gavage rotenone for 4 weeks. applied at "Baihui" (GV20), "Quchi" (LI11) "Zusanli" (ST36) 20 min, once a day 14 days, 2-day rest after every 5-day treatment....