Xinyu Li

ORCID: 0000-0003-4388-4240
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About
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Research Areas
  • Adenosine and Purinergic Signaling
  • Advanced biosensing and bioanalysis techniques
  • CRISPR and Genetic Engineering
  • Neuroendocrine Tumor Research Advances
  • Endometriosis Research and Treatment
  • Liver Disease Diagnosis and Treatment
  • Advanced Biosensing Techniques and Applications
  • HER2/EGFR in Cancer Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Anorectal Disease Treatments and Outcomes
  • Colorectal Cancer Surgical Treatments
  • Neurological Complications and Syndromes
  • Fibroblast Growth Factor Research
  • Nanoplatforms for cancer theranostics
  • Sulfur Compounds in Biology
  • Lung Cancer Research Studies
  • Mast cells and histamine
  • Infrared Thermography in Medicine
  • Apelin-related biomedical research
  • Autoimmune and Inflammatory Disorders Research
  • Kruppel-like factors research
  • Protist diversity and phylogeny
  • Cancer Immunotherapy and Biomarkers
  • Environmental Changes in China
  • Spectroscopy and Chemometric Analyses

Fujian Medical University
2024

Northeast Agricultural University
2024

Shandong First Medical University
2023

Weifang Medical University
2020-2023

Academy of Medical Sciences
2023

Shandong Tumor Hospital
2023

Shanghai Jiao Tong University
2020

Renji Hospital
2020

China Pharmaceutical University
2018

State Key Laboratory of Natural Medicine
2018

Tumor necrosis factor α (TNF-α) is used as a biomarker for the diagnosis of various inflammatory and autoimmune diseases. In recent years, numerous approaches have been qualitative quantitative analyses TNF-α. However, these methods several drawbacks, such tedious time-consuming process, high pH temperature sensitivity, increased chances denaturation in vitro. Quenchbody (Q-body) fluorescence immunoprobe that functions based on principle photoinduced electron transfer has successful...

10.1021/acsomega.1c03941 article EN cc-by-nc-nd ACS Omega 2021-11-11

The incidence of digestive malignancies has increased in recent years, including colorectal cancer (CRC), hepatocellular carcinoma (HCC) and pancreatic cancer. Advanced stages these cancers are prone to metastasis, which seriously reduce the standard living patients lead decline survival rate patients. So far there no good specific drugs stop this phenomenon. It is very important urgent find new biomarkers therapeutic targets. Purinergic ligand-gated ion channel 7 receptor (P2X7R) ATP-gated...

10.1097/cej.0000000000000851 article EN European Journal of Cancer Prevention 2023-11-06

MicroRNA (miRNA) is a promising biomarker for early diagnosis of pancreatic cancer. To enable sensitive and reliable miRNA detection, we have developed one-pot isothermal CRISPR/Dx detection system by combining...

10.1039/d4ay01695e article EN Analytical Methods 2024-01-01

Peptides have been extensively studied in nanomedicine with great bioactivity and biocompatibility; however, their poor cell-membrane-penetrating properties nonselectivity greatly limit clinical applications. In this study, tumor-targeting therapy was achieved by modifying our previously developed efficient peptide vector the cancer-targeting RGD, enabling it to specifically target tumor cells a high expression of RGD-binding receptors. B-cell lymphoma-2 antisense oligonucleotides were...

10.1021/acs.bioconjchem.4c00324 article EN Bioconjugate Chemistry 2024-12-23

Abstract Background Colorectal cancer(CRC) is currently the third most common cancer in world. It usually metastasizes through lymphatic, blood, and intraperitoneal implantation. However, rectal combined with perineal invasion after treated chemotherapy very rare. Case presentation: A 53-year-old male patient had a history of developed recto-perineal fistula redness, swelling pain scrotum repeated chemotherapy. After CT examination investigative observation, was diagnosed fistula. surgical...

10.21203/rs.3.rs-3413247/v1 preprint EN cc-by Research Square (Research Square) 2023-10-12
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