A5079267140- Advanced Fiber Laser Technologies
- Orbital Angular Momentum in Optics
- Photonic Crystal and Fiber Optics
- Cancer, Lipids, and Metabolism
- Cardiovascular and exercise physiology
- Traumatic Brain Injury and Neurovascular Disturbances
- Traditional Chinese Medicine Studies
- Adipose Tissue and Metabolism
- Advanced Fiber Optic Sensors
- Acupuncture Treatment Research Studies
- Metabolism, Diabetes, and Cancer
- Obesity, Physical Activity, Diet
- Healthcare and Venom Research
- Cancer, Hypoxia, and Metabolism
- Growth Hormone and Insulin-like Growth Factors
- Tea Polyphenols and Effects
- Prostate Cancer Treatment and Research
- Radiomics and Machine Learning in Medical Imaging
- Catalytic Processes in Materials Science
- Bone health and osteoporosis research
- Bone and Joint Diseases
- Laser-Matter Interactions and Applications
- Cardiovascular Disease and Adiposity
- Gestational Diabetes Research and Management
- Chronic Kidney Disease and Diabetes
Wuhan University
2008-2025
Renmin Hospital of Wuhan University
2008-2025
Dalian Medical University
2025
First Affiliated Hospital of Dalian Medical University
2025
Beijing Sport University
2013-2024
Kunming University of Science and Technology
2024
Wuhan University of Science and Technology
2024
Peking University People's Hospital
2024
Peking University
2024
Ningbo University
2024
Impaired apoptosis is one of the hallmarks cancer. Caspase-3 and -8 are key regulators apoptotic response have been shown to interact with calpain family, a group cysteine proteases, during tumorigenesis. The current study sought investigate prognostic potential caspase-3 in breast cancer, as well value combinatorial caspase expression. A large cohort (n = 1902) early stage invasive cancer patients was used explore expression -8. Protein examined using standard immunohistochemistry on tissue...
Abstract Background Emerging evidence supports the pivotal roles of adipocytes in breast cancer progression. Tumour induced beige/brown adipose tissue differentiation contributes to hypermetabolic state cancer. However, mediators and mechanisms remain unclear. Methods Survival probabilities were estimated using Kaplan–Meier method based on immunohistochemistry results. Biochemical studies performed characterize novel interrelation between cells adipocytes. Results We show that...
This study was to present the 2016 prevalence estimates of Chinese school-aged children meeting physical fitness standards and examine differences by sex residence locales in who did not meet standards.We conducted cross-sectional analyses 171,991 adolescents (boy: 50.0%, Grades 1-12) participated Physical Activity Fitness China-The Youth Study. The main outcomes were measures, assessed 2014 revised National Student Standard (CNSPFS), covering areas aerobic capacity, upper body strength,...
Abstract Background Precise and rapid ultrasound‐based breast cancer diagnosis is essential for effective treatment. However, existing ultrasound image segmentation methods often fail to capture both global contextual features fine‐grained boundary details. Purpose This study proposes a dual‐branch network architecture that combines the Swin Transformer Segment Anything Model (SAM) enhance (BUSI) accuracy reliability. Methods Our integrates attention mechanism of with detection from SAM...
Background: Quantitative flow ratio (QFR) is a tool for physiological lesion assessment based on invasive coronary angiography. Aims:We aimed to assess the reproducibility of QFR computed from same angiograms as assessed by multiple observers different, international sites.Methods: We included 50 patients previously enrolled in dedicated studies.QFR was twice, one month apart five blinded observers.The main analysis coefficient variation (CV) measure intra-and inter-observer...
Abstract Conversion of CO 2 and CH 4 into syngas offers a promising route to reduce emissions greenhouse gases, which facilitates large‐scale carbon fixation boosts carbon‐neutral goal. The main obstacle for /CH reforming is the lack durable catalysts showing both high metal‐exposure high‐temperature structure stability, since reported Ni‐based have difficulty in avoiding deactivation by sintering metal at temperature. Herein, ultra‐small Ni nanoparticles, display multiple characteristics...
Diabetic muscle atrophy is an inflammation-related complication of type-2 diabetes mellitus (T2DM). Even though regular exercise prevents further deterioration atrophic status, there no effective mediator available for treatment and the underlying cellular mechanisms are less explored. In this study, we investigated therapeutic potential MCC950, a specific, small-molecule inhibitor NLRP3, to treat pyroptosis diabetic in mice. Furthermore, used MCC950 intervene protective effects aerobic...
The mechanisms regulating vascular smooth muscle cell (VSMC) phenotype switching and the critical signal modulation affecting VSMCs remain controversial. Physical exercise acts as an effective drug in preventing elevated blood pressure improving function. This study was designed to explore influence of aerobic on suppression VSMC by balancing Akt, also known PKB (protein kinase B) mitogen-activated protein (MAPK) signaling pathways. Spontaneously hypertensive rats (SHRs) normotensive were...
Breast cancer is one of the most prevalent diseases for women worldwide. Early and accurate ultrasound image segmentation plays a crucial role in reducing mortality. Although deep learning methods have demonstrated remarkable potential, they still struggle with challenges images, including blurred boundaries speckle noise. To generate segmentation, this paper proposes Edge-Aware Multi-Scale Group-Mix Attention Network (EMGANet), which generates by integrating edge features. The Group Mix...
Introduction: Doxorubicin (DOX), a potent anthracycline, is widely used in cancer therapy, but its’ effect limited by DOX-induced cardiotoxicity (DIC). Increasing evidence suggests that DIC associated with ferroptosis, cell death characterized the iron-dependent accumulation of lipid peroxides. Although aerobic exercise recommended for chemotherapy-related cardiac dysfunction, extent to which its protective effects against are mediated through inhibition ferroptosis remains largely unclear....
Our study was conducted to explore the link between oxidative balance score (OBS) and rheumatoid arthritis (RA).
Background: Gut barrier integrity plays a crucial role in the pathogenesis of metabolic dysfunction-associated fatty liver disease (MAFLD). Electroacupuncture (EA) at ST-36 can ameliorate inflammatory responses via stimulating α7 nicotinic acetylcholine receptor (α7nAChR), but whether EA is effective preserving intestinal MAFLD has not been exactly illustrated. This investigation explored potential protection mechanisms targeting dismantled gut MAFLD. Methods: C57BL/6 mice were randomly...
Background: Neoadjuvant therapy (NAT) for breast cancer requires effective monitoring to assess the treatment response. To optimize strategies, early prediction of therapeutic response is crucial. This study evaluated predictive performance three ultrasound models—the longest axis model (LAM), dual axes (DAM), and manual segment (MSM)—with a focus on cycles, relationship between tumor shrinkage probability pathologic complete (pCR). Methods: In total, 121 patients (with 942 images) at Renmin...
Introduction: Previous phase 3 FOHAIC-1 study demonstrated that hepatic arterial infusion chemotherapy (HAIC) of FOLFOX regimen displayed favorable outcomes in advanced hepatocellular carcinoma (HCC) patients, including those with high-risk features (main portal tumor invasion and > 50% liver infiltration). This aimed to compare the treatment efficacy HAIC-FOLFOX versus atezolizumab-bevacizumab HCC patients. Methods: Individual patient data from Chinese aggregate global IMbrave150 were...
Aggressive growth of primitive and immature cells in the bone marrow results reductions megakaryocyte platelet (PLT) counts, leading to thrombocytopenia acute myeloid leukemia (AML). However, not all AML patients show at time diagnosis, association PLT count with patient survival is largely unknown.A retrospective study was performed determine counts diagnosis peripheral blood 291 newly diagnosed assess overall (OS) disease-free (DFS) these patients.Low (≤40 × 109/L) were associated better...
Random fiber lasers are of tremendous interest to diverse applications for optical sensing, speckle-free imaging. To date, random with fundamental mode oscillation have been well developed. However, controllable oscillating spatial in not reported yet. Here, we propose and demonstrate a few-mode laser switchable based on injection locking. An external signal light is injected realize the locking transverse this direct oscillations mode, hybrid high order can be realized, respectively. This...