A5100630640- Retinal Diseases and Treatments
- Retinal and Macular Surgery
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Vascular Malformations Diagnosis and Treatment
- Ophthalmology and Visual Impairment Studies
- Health disparities and outcomes
- Neuroinflammation and Neurodegeneration Mechanisms
- Angiogenesis and VEGF in Cancer
- Nanoplatforms for cancer theranostics
- Surgical Simulation and Training
- MicroRNA in disease regulation
- Pluripotent Stem Cells Research
- Corneal Surgery and Treatments
- Vestibular and auditory disorders
- Glycosylation and Glycoproteins Research
- Traditional Chinese Medicine Analysis
- Cancer survivorship and care
- Blood Pressure and Hypertension Studies
- Ocular Oncology and Treatments
- Neurological Disease Mechanisms and Treatments
- Inflammatory Biomarkers in Disease Prognosis
University of Jinan
2025
Shanghai First People's Hospital
2015-2024
Shanghai Jiao Tong University
2015-2024
Shanghai Eye Disease Prevention & Treatment Center
2021-2024
First Affiliated Hospital of Jiangxi Medical College
2023-2024
Jiangxi Provincial People's Hospital
2015-2024
Beijing Sport University
2024
University of Lusaka
2023
Shanghai Clinical Research Center
2023
National Clinical Research
2020-2023
High levels of dietary sodium are associated with raised blood pressure and adverse cardiovascular health. To determine baseline salt intake, we investigated the average intake from 24-hour urinary excretion a small sample Yantai adults in Shandong province China.One hundred ninety one aged 18-69 years were randomly selected adult population. Blood pressure, anthropometric indices urine collection measured. Consumption condiments was derived 3-day weighted records. Completeness collections...
Inflammatory kidney disease is a major clinical problem that can result in end-stage renal failure. In this article, we show Ab-mediated inflammatory injury and mouse nephrotoxic serum nephritis model was inhibited by amino acid metabolism protective autophagic response. The metabolic signal driven IFN-γ-mediated induction of indoleamine 2,3-dioxygenase 1 (IDO1) enzyme activity with subsequent activation stress response dependent on the eIF2α kinase general control nonderepressible 2 (GCN2)....
Introduction: Previous studies have suggested that sensory loss is linked to falls. However, most of these were cross-sectional designed, focused on single loss, and conducted in developed countries with mixed results. The current study aims investigate the longitudinal relationship between hearing (HL), vision (VL) dual (DSL) falls among middle-aged older Chinese population over 7 years. Methods: data was obtained from China Health Retirement Longitudinal Survey (CHARLS). In total, 7,623...
Purpose: To investigate the cross-sectional and longitudinal associations between sensory impairments including single vision impairment (SVI), hearing (SHI) dual (DSI) with social isolation in middle-aged older Chinese population. Methods: Data was obtained from China Health Retirement Longitudinal Survey (CHARLS). In total, 11,674 adults aging over 45 were included at baseline 2011, 6,859 participants who accomplished all 4 interviews 2011 to 2018 adapted for analyses. Sensory status...
To evaluate the influence of systemic and ocular factors on foveal avascular zone (FAZ) area in young Chinese subjects' healthy eyes.The current observational, cross-sectional study included 344 eyes from 172 individuals (103 women, 69 men). Optical coherence tomography angiography realized with split-spectrum amplitude-decorrelation (SSADA) algorithm was used to assess superficial FAZ. determine related reveal their potential correlations FAZ area, comprehensive examinations including both...
Introduction: Doxorubicin (DOX), a potent anthracycline, is widely used in cancer therapy, but its’ effect limited by DOX-induced cardiotoxicity (DIC). Increasing evidence suggests that DIC associated with ferroptosis, cell death characterized the iron-dependent accumulation of lipid peroxides. Although aerobic exercise recommended for chemotherapy-related cardiac dysfunction, extent to which its protective effects against are mediated through inhibition ferroptosis remains largely unclear....
Purpose: To evaluate the short-term influence of uncomplicated phacoemulsification on fundus structure and vasculature change.Methods: A total 51 eyes from patients with mild-to-moderate cataracts were included. Retinal vessel density, perfusion layer thickness in both macular peripapillary areas scanned by OCT at baseline 1 day, week, month after cataract surgery. Cumulative dissipated energy (CDE), U/S time (USTT) aspiration (TAT) recorded as parameters surgical injury to analyze...
Previous studies on longitudinal sensory-cognition association are limited and have yielded inconsistent conclusions in western developed countries. The present study obtained data from the China Health Retirement Longitudinal Survey (CHARLS, 2011−2018) aimed to investigate effects of sensory impairments including single vision impairment (SVI), hearing (SHI), dual (DSI) cognitive decline middle-aged older Chinese population. In total, 11,122 participants accomplished all 4 interviews over 8...
Abstract Background To investigate different tamponade effects of intravitreal silicone oil (SO) and sterilized air on macular vasculature structure after successful retinal repair for macular-on rhegmatogenous detachment (RRD) patients. Method 21 eyes (21 patients) with RRD underwent single pars plana vitrectomy following SO or (Gas) tamponade. Optical Coherence Tomography (OCT) angiography were used to evaluate layer thickness flow density (FD) changes throughout the observation period 12...
Background Subjective functional outcomes measurements, such as vision health-related quality of life (VRQoL) and self-rated satisfaction measures can provide helpful multidimensional health information that is more comprehensive than traditional objective measures, best corrected visual acuity (BCVA). The purpose this study to demonstrate 3-year longitudinal postoperative VRQoL changes after rhegmatogenous retinal detachment (RRD) surgery. Methodology/Principal Findings A prospective case...
The wet form of age-related macular degeneration (AMD) is a leading cause blindness among elderly Americans and characterized by abnormal vessel growth, termed choroidal neovascularization (CNV). Integrin α5β1 transmembrane receptor that binds matrix macromolecules proteinases to stimulate angiogenesis. We recently demonstrated integrin plays critical role in the development neovascularization. In this study, we determined underlying mechanisms angiogenesis human endothelial cells evaluated...
Abstract Background To determine the predictive value of quantitative morphological parameters for pigment epithelial detachment (PED) neovascular age-related macular degeneration (nAMD) patients. Methods One eye from each 159 patients with nAMD were studied. Polypoidal choroidal vasculopathy (PCV) group included 77 eyes, and non-PCV 82. Patients received conbercept 0.05 ml (0.5 mg) in a 3 + ProReNata (PRN) treatment regimen. Correlations between retinal morphologic at baseline...
Abstract Aims To find potential relation between retrobulbar vessels and fundus microvessels to detect sensitive effective clinical indicators in predicting the progress of diabetic retinopathy (DR), ocular hemodynamics were measured using superb microvascular imaging (SMI) ultrawide-field optical coherence tomography angiography (UWF-OCTA). Methods Observational, cross-sectional study evaluating patients with DR by SMI (Aplio i900, Canon Medical) UWF-OCTA (BM-400 K BMizar, Tupai Medical...
Infertility can lead to significant psychological distress among women, yet the roles of hope and resilience in mitigating depressive symptoms remain inadequately explored, particularly within Chinese context. We performed a cross-sectional observational study investigate impacts infertility women as well discern whether influence their symptoms. recruited 364 seeking treatment Shandong region. Participants completed validated assessments including Hospital Anxiety Depression Scale,...
Purpose Aimed to assess the impact of wearable device-based aerobic exercise on physical and mental well-being women with breast cancer (BC) undergoing chemotherapy. Methods Forty adult BC who underwent anthracycline-based chemotherapy were randomly allocated group ( n = 21) or control 19). Both groups received standard health education oncology care. In addition, wore devices engage in moderate high-intensity (50–90% HRmax) during chemotherapy, while did not carry out intervention....
The purpose of this study was to evaluate metabolic changes in the aqueous humor rabbits after administration glucocorticosteroids.Twenty-four New Zealand white were divided into following three groups: control (intravitreal injection sterile saline solution), TA triamcinolone acetonide), and DEX (subconjunctival dexamethasone). Intraocular pressure (IOP), flash electroretinogram (FERG), visual evoked potential (FVEP) tested. acquired pre-injection at 1 30 days post-injection. samples...
The aim was to elucidate the regulatory function of miR-652-3p on lipid metabolism and inflammatory cytokine secretion macrophages in atherosclerosis.miR-652-3p level atherosclerosis patients, ox-LDL-treated macrophages, their controls were monitored by Q-PCR. After ox-LDL treatment mimic, si-TP53 transfection, ELISA, Q-PCR assays used detect IL-1ß, IL-6, TNF-α levels. oil red O staining processed verify cholesterol accumulation. CE/TC also detected. protein levels ABCA1, ABCG1, PPARα, CRT1,...
Accurate segmentation of retinal images can assist ophthalmologists to determine the degree retinopathy and diagnose other systemic diseases. However, structure retina is complex, different anatomical structures often affect fundus lesions. In this paper, a new strategy called dual stream network embedded into conditional generative adversarial proposed improve accuracy lesion segmentation. First, encoder utilize capabilities two networks extract more feature information. Second, multiple...