A5058557600- Obesity, Physical Activity, Diet
- Physical Activity and Health
- Per- and polyfluoroalkyl substances research
- Birth, Development, and Health
- Urban Transport and Accessibility
- Effects and risks of endocrine disrupting chemicals
- Children's Physical and Motor Development
- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Injury Epidemiology and Prevention
- Toxic Organic Pollutants Impact
- Pregnancy and Medication Impact
- Gestational Diabetes Research and Management
- Climate Change and Health Impacts
- Pesticide Exposure and Toxicity
- Child Development and Digital Technology
- Pregnancy and preeclampsia studies
- Vitamin D Research Studies
- Traffic and Road Safety
- Eating Disorders and Behaviors
- Traumatic Brain Injury Research
- Health, Environment, Cognitive Aging
- Sleep and related disorders
- Trace Elements in Health
- Energy and Environment Impacts
Health Canada
2020-2025
Children's Hospital of Eastern Ontario
2012-2024
Queen's University
2015-2022
University of Ottawa
2012-2016
Public Health Agency of Canada
2016
Conference Board of Canada
2016
McMaster University
2016
The primary aim of this study was to develop an assessment the fundamental, combined, and complex movement skills required support childhood physical literacy. secondary establish feasibility, objectivity, reliability evidence for assessment.
This project examined the feasibility, validity, and reliability of plank isometric hold for children 8–12 years age. 1502 (52.5% female) performed partial curl-up and/or protocols to assess feasibility ( n = 823, 52.1% girls), validity 641, 54.1% girls) 111, 47.8% girls). 12% 52/431) could not perform a curl-up, but virtually all 1066/1084) attain nonzero score plank. Plank performance without time limit was influenced by small effects with age (β 6.86; p < .001, η 2 0.03), flexibility...
During pregnancy, women who experience certain pregnancy complications show elevations in biomarkers of inflammation and insulin resistance; however, few studies have examined these cardiometabolic the decade following pregnancy. To examine association between 9 years postpartum including: blood pressure, lipids, body fat percentage, resistance (glucose, insulin, proinsulin, C-peptide, HOMA-IR, HbA1c, leptin, adiponectin) (hs-C-reactive protein). Using data from Maternal-Infant Research on...
The solvents N-methyl-2-pyrrolidone (NMP) and N-ethyl-2-pyrrolidone (NEP) are established developmental toxicants; however, epidemiological data lacking. We quantified associations between urinary NEP NMP metabolites concentrations pregnancy outcomes in participants enrolled the pan-Canadian Maternal-Infant Research on Environmental Chemicals study (n = 1865) (2008-2011). Using discrete time survival analysis logistic regression, we calculated odds of preterm birth (PTB) fetal loss. used...
Demographic, family, and home characteristics play an important role in determining childhood sedentary behaviour. The objective of this paper was to identify correlates total time (SED) self-reported screen (ST) Canadian children.Child- parent-reported household, socio-demographic, behavioural, diet related data were collected; directly measured anthropometric accelerometer also collected for each child. Participants with complete demographic, anthropometric, either SED (n=524, 41% boys) or...
Perfluoroalkyl substances (PFAS) have been linked with a number of developmental, reproductive, hepatic, and cardiovascular health outcomes. However, the evidence for an association between PFAS hypertensive disorders pregnancy (including gestational hypertension preeclampsia) is equivocal warrants further investigation. To examine relationship background levels perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorohexane (PFHxS) development or preeclampsia in Canadian...
Objective Investigate whether resuming physical activity (PA) at 72 hours post concussion is safe and reduces symptoms 2 weeks, compared with resting until asymptomatic. Methods Real-life conditions, multicentre, single-blinded randomised clinical trial, conducted in three Canadian paediatric emergency departments (ED). Children/youth aged 10–<18 years acute were recruited between March 2017 December 2019, randomly assigned to a 4-week stepwise return-to-PA protocol even if symptomatic...
Abstract Background Perfluoroalkyl substances can disrupt hepatic metabolism and may be associated with liver function biomarkers. We examined individual mixture associations of PFAS on biomarkers in a representative sample Canadian adults. explored the potential for effect modification by sex body mass index, as well physical activity level which attenuate deleterious metabolic disorders. Methods analyzed data from participants aged 20–74 Health Measures Survey. used linear regression to...
Glyphosate is the most widely applied herbicide in agriculture. Glufosinate a broad spectrum used to manage glyphosate-resistant weeds. Despite widespread use of these herbicides, biomonitoring data – which inform risk assessment and management are sparse. To identify determinants urinary concentrations herbicides their metabolites pregnancy. We measured glyphosate, glufosinate, primary aminomethylphosphonic acid (AMPA) 3-methylphosphinicopropionic (3-MPPA) single spot urine specimen...
Toxic metals, such as lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg), may be associated with a higher risk of gestational hypertension preeclampsia, whereas manganese (Mn) is an essential metal that protective.
Abstract Background Several legacy and emerging per- polyfluoroalkyl substances (PFAS) have been regulated around the world. There is growing concern over proliferation of alternative PFAS, as well PFAS precursors. Biomonitoring data for are critical assessing exposure human health risk. Methods We collected serum samples from 289 adult female participants in a 2018–2021 follow-up study Maternal-Infant Research on Environmental Chemicals (MIREC) Canadian pregnancy cohort. Samples were...
To examine independent and combined associations among objectively measured movement/non-movement behaviors (moderate-to-vigorous-intensity physical activity (MVPA), total sedentary time sleep duration) adiposity indicators in a sample of Canadian children.A cross-sectional study was conducted on 507 children aged 9-11 years from Ottawa, Canada. Movement/non-movement were assessed using an Actigraph GT3X+ accelerometer over 7 days (24-h protocol). Outcomes included percentage body fat...
Summary Cross‐sectional associations between objectively‐measured sleep duration, efficiency and timing with adiposity physical activity were examined in a cohort of 567 children from Ottawa, Canada. Five‐hundred fifteen (58.8% female; age: 10.0 ± 0.4 years) had valid measurements included the present analyses. Physical activity, sedentary time parameters assessed over 7 days (actigraphy). Height, weight waist circumference measured according to standardized procedures. Percentage body fat...
Toxic metals, like lead, are risk factors for preterm birth (PTB), but few studies have examined low levels found in most Canadians. Vitamin D, which may antioxidant activity, protects against PTB. In this study, we investigated the impact of toxic metals (lead, mercury, cadmium and arsenic) on PTB if maternal plasma vitamin D concentrations modify these associations. We whether whole blood measured early late pregnancy were associated with (<37 weeks) spontaneous 1851 live births from...
Abstract Background The pan‐Canadian Maternal–Infant Research on Environmental Chemicals (MIREC) study was established to determine whether maternal environmental chemical exposures were associated with adverse pregnancy outcomes in 2001 pregnant women. Objectives MIREC‐Child Development (CD PLUS) followed this cohort the goal of assessing potential effects prenatal anthropometry and neurodevelopment early childhood. Population MIREC families children between ages 15 months 5 years who had...
Active school transport (AST) is an important source of children's daily physical activity (PA). However, decreasing rates AST have been reported in multiple countries during the last decades. The purpose present study was to examine socio-demographic and school-level correlates AST. A stratified sample children (N = 567, mean age 10.0 years; 57.8% female) recruited Ottawa area. Four sources data were used for analyses: 1) child questionnaire including questions on travel mode time; 2)...
The relationships among sedentary time, television viewing and dietary patterns in children are not fully understood. aim of this paper was to determine which self-reported time or objectively measured is a better correlate the frequency consumption healthy unhealthy foods. A cross-sectional study conducted 9- 11-year-old (n = 523; 57.1% female) from Ottawa, Ontario, Canada. Accelerometers were used total questionnaires number hours watching foods per week. Television negatively associated...
Having a TV in the bedroom is associated with adiposity children. It not known how lifestyle behaviours (television viewing time, diet patterns, physical activity, and sleep duration) mediate this association. The objective of study was to examine mediating role these association between percent body fat (% BF).
The purpose of this study was to determine the validity SC-StepRx pedometer assess moderate and vigorous physical activity during treadmill walking running in a heterogeneous sample children youth aged 10-17 years. Physical intensity assessed via indirect calorimetry served as criterion standard. A convenience 40 participants (20 boys, 20 girls) wore 6 pedometers, 2 ActiGraph GT3X accelerometers, Actical 1 Walk4Life MVP NL-1000 while walking/running at speeds approximating 2, 3, 4, 7 METs....
Background: Per- and polyfluoroalkyl substances (PFAS) are persistent environmental contaminants that induce immunotoxicity in experimental studies; however, epidemiological evidence—particularly during pregnancy—is scarce. We quantified associations between first trimester plasma perfluorooctanoic acid (PFOA), perfluorooctane sulfonate (PFOS), perfluorohexane (PFHxS) concentrations third of inflammatory biomarkers determined if these were modified by fetal sex. Methods: analyzed data from...
Importance Determining the optimal volume of early moderate-to-vigorous-intensity physical activity (MVPA) after concussion and its association with subsequent symptom burden is important for postinjury management recommendations. Objectives To investigate between cumulative MVPA (cMVPA) over 2 weeks at 1 week, weeks, 4 in children examine cMVPA odds persisting symptoms (PSAC) postinjury. Design, Setting, Participants This multicenter cohort study used data from a randomized clinical trial...
Per- and polyfluoroalkyl substances (PFAS) are ubiquitous chemicals routinely detected in personal care products (PCPs). However, few studies have evaluated the impact of PCP use on PFAS concentrations pregnant lactating populations. We investigated associations between prenatal plasma human milk. leveraged Maternal-Infant Research Environmental Chemicals (MIREC) Study to evaluate contribution (6 13 weeks' gestation; n = 1,940) human-milk (2 10 postpartum; 664). Participants reported...