A5102811720- Cardiac Imaging and Diagnostics
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Lung Cancer Treatments and Mutations
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Gastric Cancer Management and Outcomes
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Adipose Tissue and Metabolism
- Cardiac electrophysiology and arrhythmias
- Gastrointestinal Tumor Research and Treatment
- Cardiac Structural Anomalies and Repair
- Medical Imaging and Pathology Studies
- MicroRNA in disease regulation
- Advanced X-ray and CT Imaging
- Cardiovascular Effects of Exercise
- Cancer-related molecular mechanisms research
- Cerebrovascular and Carotid Artery Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Coronary Interventions and Diagnostics
Soochow University
2016-2025
University of Bern
2025
University Hospital of Bern
2025
Changzhou No.2 People's Hospital
2023-2024
Changzhou University
2020-2023
The First People's Hospital of Changzhou
2023
Soochow University
2020-2021
Christie's
2015
University of Maryland, Baltimore
2014
VA Maryland Health Care System
2014
OBJECTIVE. The purpose of this study was to explore the value FDG PET combined with high-resolution CT (HRCT) in predicting pathologic subtypes and growth patterns early lung adenocarcinoma. MATERIALS AND METHODS. A retrospective analysis conducted on PET/CT data ground-glass nodules (GGNs) resected from patients stage IA efficacy maximum standardized uptake (SUVmax) HRCT signs prediction histopathologic subtype pattern adeno-carcinoma evaluated. RESULTS. SUVmax significantly higher GGNs...
Abstract Background To introduce a three-dimensional convolutional neural network (3D CNN) leveraging transfer learning for fusing PET/CT images and clinical data to predict EGFR mutation status in lung adenocarcinoma (LADC). Methods Retrospective from 516 LADC patients, encompassing preoperative images, information, status, were divided into training ( n = 404) test sets 112). Several deep models developed utilizing learning, involving CT-only PET-only models. A dual-stream model PET CT...
In diabetes, dysregulated substrate utilization and energy metabolism of myocardium can lead to heart failure. To examine the dynamic changes myocardium, most previous studies conducted myocardial PET imaging following euglycemic-hyperinsulinemic clamp, which involves complicated procedures. comparison, whole-body 18F-FDG PET/CT scan is a simple widely used method. Therefore, we hope use this method observe abnormal glucose in diabetes determine influencing factors. We retrospectively...
Previous studies have reported that long non‑coding (lnc) RNA FGD5‑antisense 1 (FGD5‑AS1) promotes tumor proliferation, migration and invasion. Therefore, the present study aimed to elucidate biological role underlying molecular mechanisms of FGD5‑AS1 in cisplatin (DDP) resistance lung adenocarcinoma (LAD) cells. The results demonstrated was highly expressed DDP‑resistant LAD tissues Knockdown decreased proliferative, migratory invasive abilities Moreover, it identified acted as a sponge for...
Background Epicardial adipose tissue may be associated with the pathogenesis of coronary artery disease (CAD), but its effect on obstructive CAD risk is uncertain. Therefore, we aimed to examine relationship between epicardial and in Chinese patients suspected CAD. Methods Results The present study enrolled 194 consecutive inpatients who underwent both noncontrast computed tomography angiography. We measured fat volume (EFV) evaluated association CAD, which was defined as stenosis severity...
This study aims to construct radiomics models based on [18F]FDG PET/CT using multiple machine learning methods predict the EGFR mutation status of lung adenocarcinoma and evaluate whether incorporating clinical parameters can improve performance models.A total 515 patients were retrospectively collected divided into a training set (n = 404) an independent testing 111) according their examination time. After semi-automatic segmentation images, features extracted, best feature sets CT, PET,...
OBJECTIVE. The purpose of this study is to evaluate high-resolution CT (HRCT) combined with PET/CT for preoperative differentiation invasive adenocarcinoma (IAC) from preinvasive lesions and minimally (MIA) (the combination which hereafter referred as preinvasive-MIA) in lung manifesting ground-glass opacity nodules (GGNs) 3 cm or smaller. MATERIALS AND METHODS. We retrospectively analyzed the data patients GGNs that were smaller between November 2011 2018. HRCT parameters compared...
Abstract Aim Atrial fibrillation (AF) is a progressive disease from paroxysmal to persistent, and persistent AF (PerAF) had worse prognosis. has potential link with inflammation, but it not clear whether PerAF or (ParAF) more closely related inflammation. On the basis of inhibiting myocardial physiological uptake, 18 F-fluorodeoxyglucosepositron emission tomography/computed tomography ( F-FDG PET/CT) an established imaging modality detect cardiac We aimed decipher association between atrial...
Abstract Background To establish and validate 18 F-fluorodeoxyglucose ( F-FDG) PET/CT-based radiomics model use it to predict the intermediate-high risk growth patterns in early invasive adenocarcinoma (IAC). Methods Ninety-three ground-glass nodules (GGNs) from 91 patients with stage I who underwent a preoperative F-FDG PET/CT scan histopathological examination were included this study. The LIFEx software was used extract 52 PET 49 CT radiomic features. least absolute shrinkage selection...
Epicardial adipose tissue (EAT) is closely related to coronary artery disease (CAD). Hemodynamically significant CAD has a worse prognosis and more likely benefit from revascularization. However, the specific relationship between EAT hemodynamically remains unclear.A total of 164 inpatients received single-photon emission computerized tomography-myocardial perfusion imaging (SPECT/MPI) angiography (CAG) March 2018 October 2019 at Third Affiliated Hospital Soochow University were enrolled in...
Background: Atrial fibrillation (AF) has been identified to increase stroke risk, even after oral anticoagulants (OACs), and the recurrence rate is high radiofrequency catheter ablation (RFCA). Inflammation an essential factor in occurrence persistence of AF. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) established molecular imaging modality detect local inflammation. We aimed investigate relationship between atrial inflammatory activity poor...
Background: In type 2 diabetes mellitus (T2DM) patients, left ventricular systolic dyssynchrony (LVSD) with normal ejection fraction (LVEF) and myocardial perfusion could referred to as subclinical damage, which is difficult diagnose at an early stage. Epicardial adipose tissue, a distinctive heart-specific visceral fat, closely related various cardiovascular diseases. The objective of this study was investigate the correlation between epicardial fat volume (EFV) damage in T2DM patients....
Atrial fibrillation (AF) is a common arrhythmia, and its most severe dreaded complication stroke. The CHA2DS2-VASc score currently recommended for stroke risk assessment in AF. We aimed to explore the relationship between atrial FDG uptake whether could provide incremental value above CHA2DS2-VAS predict AF by 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT).From September 2017 December 2020, we retrospectively enrolled 230 patients (115 with 115...
A predictive model using left atrial function indexes obtained by real-time three-dimensional echocardiography (RT-3DE) and the blood B-type natriuretic peptide (BNP) level was constructed, its value in predicting recurrence patients with early persistent fibrillation (AF) after radiofrequency ablation explored.A total of 228 AF who were scheduled to receive first circular pulmonary vein (CPVA) enrolled. Clinical data collected: (1) The BNP measured before ablation; (2) RT-3DE used obtain...
(1) Background: To investigate the association between maximum standardized uptake value (SUVmax) based on 18F-FDG PET/CT and EGFR mutation status in lung adenocarcinoma. (2) Methods: A total of 366 patients were retrospectively collected divided into group (n = 228) wild-type 138) according to their status. The two groups' general information imaging parameters compared. hierarchical binary logistic regression model was used assess interaction effect relationship SUVmax different subgroups....