A5041809455- Transplantation: Methods and Outcomes
- Lung Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Viral Infections and Immunology Research
- Tracheal and airway disorders
- Radiomics and Machine Learning in Medical Imaging
- Cardiac tumors and thrombi
- Renal Transplantation Outcomes and Treatments
- Polyomavirus and related diseases
- Voice and Speech Disorders
- Gestational Trophoblastic Disease Studies
- Gastric Cancer Management and Outcomes
- Pancreatic and Hepatic Oncology Research
- Management of metastatic bone disease
- Musculoskeletal synovial abnormalities and treatments
- Myasthenia Gravis and Thymoma
- Sympathectomy and Hyperhidrosis Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Cerebrovascular and Carotid Artery Diseases
- Pulmonary Hypertension Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- biodegradable polymer synthesis and properties
- Prion Diseases and Protein Misfolding
- Thyroid and Parathyroid Surgery
- Cancer Immunotherapy and Biomarkers
Chiba University
2017-2023
National Hospital Organization
2015-2016
Meiji Pharmaceutical University
2009
Teikyo University
1993
Kanazawa University
1993
Carcinoma cells often modulate coagulation and fibrinolysis among cancer patients. Plasma dimerized plasmin fragment D (D-dimer) has been reported as a prognostic marker of various types malignancies, including non-small cell lung (NSCLC). However, the associations between plasma D-dimer level peripheral small NSCLC remain unclear.Three hundred sixty-two patients with who underwent radical surgery were retrospectively reviewed. Patients received anticoagulation therapy before or lacked...
Sclerosing pneumocytoma is a rare lung tumor that usually recognized as solitary nodule in the lung. Surgical removal recommended; however, its clinical diagnosis still an issue because it difficult to differentiate from adenocarcinomas using tiny sample obtained biopsy.We report case of pulmonary sclerosing located upper lobe right 34-year-old woman, which was diagnosed before surgery by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). A 3-cm irregular mass...
背景.胸腺原発粘表皮癌は稀な腫瘍である.症例.29歳男性.検診にて胸部異常陰影を指摘された.胸部単純X線写真で右側縦隔から突出する腫瘤影,胸部CT検査で前縦隔に62×38×74 mmの一部造影される多房性嚢胞を認めた.胸骨正中切開にて前縦隔腫瘍摘出術を施行し,術後病理で胸腺嚢胞に合併した胸腺原発粘表皮癌と診断された.結論.胸腺嚢胞に合併した胸腺原発粘表皮癌を経験した.切除後1年4ヶ月無再発生存中である.
Background Obliterative bronchiolitis (OB) is a known issue during minor histocompatibility antigen (mHA) disparity lung transplantation. This study evaluated gene expression in murine orthotropic transplantation model using microarray analysis. Methods Left lungs from C57BL/10(H-2b) donor mice were transplanted into mHA-mismatched C57BL/6(H-2b) recipient mice. Three groups (OB, non-OB, and sham controls) confirmed pathologically analyzed. Gene changes the grafts determined by...
Antibody-mediated rejection (AMR) could induce acute or chronic graft failure during organ transplantation. Several reports have shown that anti-C5 antibodies are effective against AMR after kidney However, few assessed the efficacy of lung Therefore, this study aimed to evaluate novel therapy transplantation.BALB/c and C57BL/6 mice were used as donors recipients. One group was pre-sensitized (PS) by skin transplantation 14 days before The other non-sensitized (NS). Orthotopic left-lung...
症例は51歳，男性．左上葉大細胞癌（弓部大動脈浸潤，鎖骨上窩リンパ節転移cT4N3M0，stage IIIB）の診断で同時併用化学放射線療法を4コース施行しPRが得られたが，その後原発巣の増大を認めサルベージ手術を施行した．術前検査で対側椎骨動脈の低形成が確認されたため，弓部大動脈合併切除に際し患側椎骨動脈を再建することとした．手術は前方アプローチで行い，TMA法にて鎖骨を授動して行った．肺は部分切除とし，Yグラフトを用いて上行大動脈から左総頸動脈，左腋窩動脈へバイパスを作製，椎骨動脈分岐部は腫瘍内で露出不可能であり，下半身の部分体外循環下に遠位弓部大動脈および椎骨動脈分岐部を腫瘍と一塊に摘出し，弓部大動脈再建後に椎骨動脈をYグラフト分枝に端側吻合した．術後経過は良好で軽快退院された．対側椎骨動脈低形成を伴う縦隔型肺癌に対し遠位弓部大動脈合併切除に加え椎骨動脈再建術を施行したので報告する．
症例は65歳，女性．咳嗽・発熱で近医を受診し，胸部X線で異常を指摘され当院紹介受診．胸部CT, MRIにて左胸腔に表面平滑で境界明瞭，内部に充実成分と脂肪成分の混在する分葉状の巨大腫瘍を認めた．経皮針生検にて確定診断に至らなかったが，間葉系腫瘍を疑い手術を施行した．腫瘍は横隔膜，胸壁とは癒着を認めず，縦隔胸膜および肺底部臓側胸膜に覆われており，後縦隔から発生したものと考えられた．腫瘍は下肺静脈周囲で肺下葉内へ進展しており，腫瘍摘出および下葉切除を施行した．腫瘍の重量は1580 gで病理診断は高分化型脂肪肉腫であった．術後追加治療は行わずに慎重に経過観察中である．脂肪肉腫は四肢の軟部組織や後腹膜にしばしば発生するが，縦隔原発例は稀である．後縦隔原発巨大脂肪肉腫の1例を経験したので報告する．
54歳，男性．食道癌と胃癌にて同時切除術を行ってから5年後に定期的上部消化管内視鏡検査（GS）により早期胃管癌が発見され，内視鏡的粘膜下層剥離術（ESD）を施行した．切除標本の病理所見は，tub1～tub2，pSM1以深，LM0，VM1であった．高度肺気腫が存在したため，追加の胃管全摘術は行わず，無治療経過観察した．ESD後2年2カ月後に，GSにより胃管癌の局所再発が認められた（生検でpor）．呼吸機能低下のために，S-1による化学療法を行った．GSでは胃管癌の進行は明らかではなかったが，呼吸機能の急速な悪化により，化学療法開始後約6カ月で永眠した．病理解剖により，胃管癌全体に表層性に広がる低分化腺癌の伸展，粘膜下・漿膜下のリンパ管侵襲，両肺の高度な癌性リンパ管症，胸膜転移，心筋，骨髄など，広範な他臓器への転移が判明した．胃管癌の治療を行う上で問題を提起する1例であると考えられる．
Giant cervicomediastinal goiter extending to the bifurcation of trachea mostly requires median sternotomy in addition a cervical collar incision for resection. Sternotomy provides good operative field, although it is one most invasive thoracic approaches. We herein report case giant resected by less-invasive and highly effective method with thoracoscopic approach.