We have shown previously that norepinephrine (NE) microdialyzed into the preoptic area of conscious guinea pigs evokes a fall in core temperature (Tco) is mediated by reduction metabolic rate. To identify adrenoceptor subtype(s) involved this effect, we intrapreoptically various adrenergic agonists or antagonists singly combinations. Tco and ear skin temperatures animals were monitored throughout experiments. alpha 1-, beta-, beta 2-agonists did not induce significant changes. Although...

Abstract Aims We aimed to investigate the effect of different pulse numbers high‐frequency repetitive transcranial magnetic stimulation (rTMS) over motor cortex on cortical excitability in healthy participants. Methods Fifteen participants received 600 and 1200 pulses 5‐Hz rTMS separate days a random order. Stimulation (duration, 2 seconds interval, 1 seconds) was delivered left primary for hand, at 90% resting threshold (rMT). The rMT evoked potential (MEP) were measured before stimulation,...

Background: This study assessed the effect transcutaneous vagus nerve stimulation (TVNS) for poststroke epilepsy (PSE). Methods: Fifty-two patients with PSE were included in this study. Twenty-seven received TVNS, 30 minutes each session, once daily, twice weekly a total of 4 weeks; and assigned to treatment group. Twenty-five at waiting list control The primary outcome seizure frequency. secondary outcomes consisted episode, quality life, measured by Quality Life Epilepsy Inventory-31...

Morphine dependence (MD) is a very common complication because of the chronic morphine consumption. Studies suggest that repetitive transcranial magnetic stimulation (rTMS) can be used for treatment MD. However, there still lacking evidence to support rTMS Thus, this retrospective study aimed investigate effectiveness and safety patients with MD.In retrosepctive study, total 100 MD were included, they divided into group (n = 50), control 50). All in both groups received occupational therapy....

This study firstly investigated the feasibility effect and safety of Ganoderma Lucidum Spore Powder (GLSP) for treating patients with epilepsy. Eighteen eligible epilepsy were included. They all received GLSP treatment a total 8 weeks. The primary outcome included weekly seizure frequency. secondary outcomes consisted each episode, quality life, measured by Quality Life in Epilepsy Inventory-31 (QOLIE-31), as well adverse events (AEs). After treatment, can significant reduce frequency,...

A variety of causes may induce sudden deafness. However, it remains challenging to determine the exact cause in a clinic. There is no standard treatment for this disease due its unclear etiology.The present study aims investigate clinical efficacy intratympanic injection dexamethasone treating deafness.A total 154 patients with deafness were retrospectively analyzed. The evaluation was based on AAO-HNS evaluative criteria. All initially treated within seven days by an intravenous drip...

Abstract Studies have shown that there is heterogeneity in the efficacy bewteen low-frequency (LF) and high-frequency (HF) repetitive transcranial magnetic stimulation (rTMS), but neural mechanisms underlying differences remain unclear. This study aimed to investigate specific effects of LF- HF-rTMS on cortial functional network process regulation. A total sixty-eight patients with hemiplegic motor impairment after stroke were randomly allocated one three groups: LF-rTMS, HF-rTMS, sham...

This study aimed at exploring the effects of combined epidural anesthesia and general on cognitive function stress responses elderly patients undergoing liver cancer surgery. One hundred fifteen were enrolled as research subjects. They admitted to our hospital underwent surgery from August 2017 May 2019. Fifty five cases treated with (GA) (GA group), while other sixty (joint group). Scoring standards Mini-Mental State Examination (MMSE) used evaluate before after operation. Their operating...

The ability of transplanted induced neural stem cells (iNSCs) to promote functional recovery after spinal cord injury and the mechanism by which iNSCs migrate injured areas are poorly understood. Stromal cell-derived factor-1 (SDF-1) is a cytokine, whereas CXCR4 its cognate receptor. aim this study was determine whether SDF-1 regulates migration explore potential promotes recovery. In-vitro experiments demonstrated that induces concentration-dependent iNSCs. Pretreatment with CXCR4-specific...

Abstract Background: Microsurgery is a treatment option for dural arteriovenous fistula (DAF), but its efficacy still unclear. This study aims to assess the and safety of microsurgery patients with DAF. Methods: We will carry out this assessing use in DAF from following electronic databases: PUBMED, EMBASE, Cochrane Library, CINAHL, PsycINFO, Allied Complementary Medicine Database, Chinese Biomedical Literature China National Knowledge Infrastructure. All those databases be searched...

This systematic review aims to assess the effect of cinnamaldehyde on Cav-1 and Survivin expression in epilepsy.We will search Cochrane Library, PUBMED, EMBASE, CINAHL, Web Science, Google Scholar, PsycINFO, WANGFANG, VIP, CBM, CNKI from their inceptions March 31, 2020, without language restrictions. Two authors independently carry out searching literature records, scanning titles abstracts, full texts, collecting data, assessing risk bias. RevMan 5.3 software be used for statistical...

Morphine is tolerable after long-term use. After use, it will have a great impact on the human body, and treatment effect not good. In recent years, continuous development of repetitive transcranial magnetic stimulation (rTMS) technology has made treatment. Drug-resistant morphine dependence breakthrough. this article, to study repeated in through mGluR5/TDP43/NR2B pathway, experiments were carried out rats compare changes images different periods use their effects withdrawal. During period,...

Depression not only threatens the health and quality of life patients but also brings a huge mental economic burden to patients’ families. This paper mainly studies mechanism dopaminergic neurotransmission in different doses morphine addiction stress-induced depression. In experiment, 40 male SD rats were selected. The experiment established rat model chronic stress used this are all raised single cage, there will be various stimuli every day for 21 days, high-intensity continuous must...