A5052791636- Blood transfusion and management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Valve Diseases and Treatments
- Blood donation and transfusion practices
- Cardiac, Anesthesia and Surgical Outcomes
- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Hemodynamic Monitoring and Therapy
- Cardiac and Coronary Surgery Techniques
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrest and Resuscitation
- Child Nutrition and Feeding Issues
- Aortic Disease and Treatment Approaches
- Cardiac Imaging and Diagnostics
- Erythropoietin and Anemia Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Health and Mental Health
- Clinical Nutrition and Gastroenterology
- Selenium in Biological Systems
- Congenital Anomalies and Fetal Surgery
- Blood properties and coagulation
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Atrial Fibrillation Management and Outcomes
- Clinical Laboratory Practices and Quality Control
Prince Charles Hospital
2015-2024
New Zealand Association of Counsellors
2023
Pear Therapeutics (United States)
2023
Griffith University
2011-2022
Queensland University of Technology
2020
Menzies School of Health Research
2020
University of the Sunshine Coast
2018-2020
The University of Queensland
2011-2013
Royal Manchester Children's Hospital
1997
Boston Children's Hospital
1997
Background and Objectives Excessive bleeding is a risk associated with cardiac surgery. Treatment invariably requires transfusion of blood products; however, the itself may contribute to postoperative sequelae. Our objective was analyse quality initiative designed provide an evidenced‐based approach management. Materials Methods A retrospective analysis compared product patient outcomes 15 months before after implementation management protocol. The protocol incorporated point‐of‐care...
Cryopreservation extends platelet (PLT) shelf life from 5 to 7 days 2 4 years. However, only 73 patients have been transfused cryopreserved PLTs in published randomized controlled trials (RCTs), making safety data insufficient for regulatory approval.The Cryopreserved vs. Liquid Platelet (CLIP) study was a double-blind, pilot, multicenter RCT involving high-risk cardiothoracic surgical four Australian hospitals. The objective test, as the primary outcome, feasibility and of protocol....
Calcific aortic valve stenosis (CAVS) is an important clinical problem predominantly affecting elderly individuals. Studies suggest that the progression of CAVS actively regulated with endothelial injury leading to inflammation, fibrosis and calcification. The aim this study was delineate possible regulatory role osteopontin (OPN) on high-mobility group box 1 (HMGB1) function associated inflammatory fibrotic response in CAVS. Aortic leaflets were collected from patients undergoing...
The goal of patient blood management (PBM) is to optimize clinical outcomes for individual patients by managing their as a precious and unique resource be safeguarded managed judiciously. A corollary successful PBM the minimization or avoidance transfusion stewardship donated blood. first achieved multidisciplinary approach with personalized plans shared decided on substitute. It follows that physician-patient relationship an integral component medical practice fundamental link between...
Purpose: Excessive bleeding is an acknowledged consequence of cardiac surgery, occurring in up to 10% adult patients. This clinically important complication leads poorer patient outcomes. Clinical practice guidelines are available support best however variability management and related adverse outcomes still exist. study had two objectives: 1) gain insight into current for surgery Australia how that compared literature; 2) understand perceived difficulties clinicians face implementing...
Abstract Background Bleeding during cardiac surgery is a common complication that often requires the transfusion of blood products. The combination bleeding and product incrementally increases adverse outcomes including infection mortality. Following management guideline recommendations could assist with minimising risk but adherence not high, cause for lack well understood. This study aimed to identify barriers facilitators practicing implementing evidenced-based intra-operative, in...
Organized patient blood management (PBM) programs function in numerous hospitals and health systems around the world contributing to improved outcomes as well increased engagement, decreased resource use, reductions care costs. PBM “programming” ranges from implementation of single strategies/initiatives comprehensive led by dedicated clinicians committees, employing use multiple strategies. Frontline professionals play an important role leading, implementing, operationalizing, measuring,...
Background: Transfusion of blood components has long been considered lifesaving therapy. While transfusion may be clinically indicated as a treatment option for some patients, the benefits in asymptomatic, hemodynamically stable patients are questionable. Problem: Blood component is routinely used default therapy when not indicated, increasing risk poor patient outcomes, adverse events, pressures on supply and availability, increased health care costs. Approach: Nurses have responsibility to...
Surgery and obesity are known risk factors for thromboembolic events due to the presence of a hypercoagulable state. Rotational thromboelastometry is viscoelastic assay that can provide measure hypercoagulability via comprehensive assessment coagulation process. This prospective study investigates haemostatic changes over time, association between body mass index results in patients undergoing major orthopaedic surgery. Fifty adult total hip or knee replacement surgery had serial measures...
The prothrombotic state of obesity can increase the risk thromboembolism. We aimed to investigate if there was an association between baseline hypercoagulable rotational thromboelastometry (ROTEM) profile and thromboembolic complications in arthroplasty patients with obesity. Patients a body mass index ≥ 25 kg/m2 and/or waist circumference ≥94 cm (M) 80 (F) undergoing hip knee had pre- postoperative ROTEM. ROTEM values were compared by outcome status using independent sample equal-variance...
INTRODUCTION Myocardial injury following noncardiac surgery (MINS) is defined as troponin elevations occurring up to 30 days postoperatively in the absence of non-ischaemic causes.[1] Obesity associated with hypercoagulability, which can be diagnosed using viscoelastic assays, such rotational thromboelastometry (ROTEM).[2,3] Previous assay studies have shown a higher incidence thromboembolic and ischaemic events those hypercoagulability.[4,5] In this study, we aimed examine association...
Abstract Background Bleeding during cardiac surgery is a common complication that often requires the transfusion of blood products. The combination bleeding and product incrementally increases adverse outcomes including infection mortality. Following management guideline recommendationscould assist with minimising risk but adherence not high, cause for lack well understood. This study aimed to identify barriers facilitators practicing implementing evidenced-based in Australian units. Methods...