Ian Smith

ORCID: 0000-0002-3438-4706
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About
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Research Areas
  • Anesthesia and Sedative Agents
  • Blood transfusion and management
  • Wood Treatment and Properties
  • Cardiac, Anesthesia and Surgical Outcomes
  • Inhalation and Respiratory Drug Delivery
  • Transplantation: Methods and Outcomes
  • Airway Management and Intubation Techniques
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Nausea and vomiting management
  • Anesthesia and Pain Management
  • Mechanical Circulatory Support Devices
  • Structural Load-Bearing Analysis
  • Tracheal and airway disorders
  • Muscle metabolism and nutrition
  • Agricultural Economics and Policy
  • Sugarcane Cultivation and Processing
  • Anesthesia and Neurotoxicity Research
  • Atrial Fibrillation Management and Outcomes
  • Respiratory Support and Mechanisms
  • Platelet Disorders and Treatments
  • Global trade and economics
  • Cardiovascular and exercise physiology
  • Clinical Laboratory Practices and Quality Control
  • Firm Innovation and Growth
  • Tree Root and Stability Studies

Wake Forest University
2024

Prince Charles Hospital
2013-2024

New Zealand Association of Counsellors
2023

Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences
2022

Edinburgh Royal Infirmary
2021

Bradford Teaching Hospitals NHS Foundation Trust
2015-2020

St James's University Hospital
2020

Institute of Biomedical Science
2018

University of Oxford
2018

University of Cambridge
2018

Proteins secreted by strains of Mycobacterium tuberculosis during short-term, zinc-sufficient batch culture were identified in order to define antigens likely be relevant the pathogenesis human disease. [35S]Methionine-labelled proteins supernatants 4-7 d cultures separated PAGE under both denaturing and non-denaturing conditions, position labelled material was determined. Secreted protein patterns M. quite similar those Bacillus Calmette-Guérin (BCG) but differed absence 46 kDa dimeric...

10.1099/00221287-134-2-531 article EN Microbiology 1988-02-01

Background and Objectives Excessive bleeding is a risk associated with cardiac surgery. Treatment invariably requires transfusion of blood products; however, the itself may contribute to postoperative sequelae. Our objective was analyse quality initiative designed provide an evidenced‐based approach management. Materials Methods A retrospective analysis compared product patient outcomes 15 months before after implementation management protocol. The protocol incorporated point‐of‐care...

10.1111/vox.12279 article EN Vox Sanguinis 2015-04-30

#### What you need to know Routine preoperative investigations are expensive, labour intensive, and of questionable value, especially as they may contribute morbidity or cause additional delays due spurious results.1 2 3 4 5 Preoperative assessment clinics usually based in the hospital where surgery will occur run according local policies procedures. The number elective surgeries within NHS has risen: 10.6 million operations took place 2012-13 compared with 6.61 2002-03. Even if only a small...

10.1136/bmj.i3292 article EN BMJ 2016-07-14

Analysis of changes in the locations headquarters leading thousand companies UK, both at regional and urban levels, reveals evidence increasing centralization control Southeast. The main elements change are analysed to assess their relative significance process.

10.1068/a101073 article EN Environment and Planning A Economy and Space 1978-09-01

10.1002/1097-0142(197008)26:2<303::aid-cncr2820260210>3.0.co;2-v article EN Cancer 1970-08-01

The 1000 Years of Pharmaceutical Aerosols Conference convened posing the question; “what remains to be done?” When applying this question topic inhaler devices, two hugely different perspectives could taken. On one hand, it argued that because there is an array delivery systems available and industry, prescribing physicians patients alike have considerable choice, why would we believe necessary do anything further? other as are constantly reminded by our “customers” devices less than...

10.1089/jamp.2010.0853 article EN Journal of Aerosol Medicine and Pulmonary Drug Delivery 2010-12-01

Abstract Fifty-nine type 1 tympanoplasties in children under 14 years of age were assessed by recall to a special follow-up clinic up 15 post-operatively. Overall 78 per cent tympanic membranes found be intact with late failure grafts noted 6 cases. An improvement the audiological threshold was 51 cent, 24 unchanged, remaining 25 suffered deterioration which seen both immediately post-operatively and thereafter until reviewed clinic. The at operation, size perforation, grade surgeon carrying...

10.1017/s0022215100113854 article EN The Journal of Laryngology & Otology 1990-10-01

Smith I. J. (1979) The effect of external takeovers on manufacturing employment change in the Northern region between 1963 and 1973, Reg. Studies 13, 421–437. This analysis attempts to assess differential performance externally acquired plants with over 100 workers region. evidence for regarding this ownership category as potentially a distinctive one terms is first reviewed. It hypothesised that such may be characterised by above-average growth pre-merger period, subsequently rate curtailed...

10.1080/09595237900185371 article EN Regional Studies 1979-10-01

The topic of incurred sample stability (ISS) has generated considerable discussion within the bioanalytical community in recent years. subject was an integral part seventh annual Workshop on Recent Issues Bioanalysis (WRIB) held Long Beach, CA, USA, April 2013, and at Global CRO Council for (GCC) meeting preceding it. Discussion both events focused use samples ISS purposes light results from a GCC survey completed by member companies. This paper reports consensus resulting these discussions...

10.4155/bio.14.155 article EN Bioanalysis 2014-09-01

All current metered dose inhalers (MDIs) contain chlorofluorocarbons (CFCs) as the propellant. Two alternative hydrofluoroalkane propellants, HFA134a (tetrafluoroethane) and HFA227 (heptafluoropropane), are being investigated. The replacement of CFCs by HFAs has a major impact on all aspects MDI from basic formulation to tests required assess performance. commonly used surfactants essentially insoluble in HFA propellants. performance metering valve is critical reproducible delivery drug an...

10.1089/jam.1995.8.suppl_1.s-19 article EN Journal of Aerosol Medicine 1995-01-01

PITSILADIS, Y. P., I. SMITH, and R. J. MAUGHAN. Increased fat availability enhances the capacity of trained individuals to perform prolonged exercise. Med. Sci. Sports Exerc., Vol. 31, No. 11, pp. 1570–1579, 1999. Methods: After a familiarization period, six well-trained males participated in diet exercise regimen lasting 9 d comprising three cycling tests exhaustion. A work rate was selected during period that would result fatigue after approximately 90–100 min at an ambient temperature...

10.1097/00005768-199911000-00012 article EN Medicine & Science in Sports & Exercise 1999-11-01

10.1016/j.ijoa.2008.11.007 article EN International Journal of Obstetric Anesthesia 2009-02-10

OBJECTIVE Complications have been used extensively to facilitate evaluation of craniosynostosis practice. However, description complications tends be nonstandardized, making comparison difficult. The authors propose a new pragmatic classification that relies on prospective data collection, is geared capture significant morbidity as well any "near misses" in systematic fashion, and can quality improvement tool. METHODS Data for all patients undergoing surgery nonsyndromic between 2010 2015...

10.3171/2017.1.peds16343 article EN Journal of Neurosurgery Pediatrics 2017-03-31

THE ARTHRITIS AND RHEUMATISM COUNCIL'S NATIONAL REPOSITORY OF FAMILY MATERIAL: PEDIGREES FROM FIRST 100 RHEUMATOID FAMILIES CONTAINING AFFECTED SIBLING PAIRS J. WORTHINGTON, WORTHINGTON *ARC Epidemiology Research Unit, Manchester UniversityThe Stopford Building, Oxford Road, Ml3 9PT Search for other works by this author on: Academic PubMed Google Scholar W. E. R. OLLIER, OLLIER M. K. LEACH, LEACH I. SMITH, SMITH HAY, HAY THOMSON, THOMSON L. PEPPER, PEPPER D. CARTHY, CARTHY A. FARHAN, FARHAN...

10.1093/rheumatology/33.10.970 article EN Lara D. Veeken 1994-01-01

Background . Damage to the endothelium has been established as a key pathological process in lung transplantation and ex vivo perfusion (EVLP), new technology that provides platform for assessment of injured donor lungs. endothelial glycocalyx, structure lines is integral vascular barrier function, associated with dysfunction. We hypothesised glycocalyx shedding occurs during EVLP aimed establish porcine model investigate mechanism underlying breakdown EVLP. Methods Concentrations products,...

10.1155/2019/6748242 article EN cc-by Journal of Transplantation 2019-08-25
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