A5090839379- Global Maternal and Child Health
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical Economics and Policy
- Antibiotic Use and Resistance
- Health Systems, Economic Evaluations, Quality of Life
- Vaccine Coverage and Hesitancy
- HIV/AIDS Research and Interventions
- Malaria Research and Control
- Reproductive Health and Contraception
- COVID-19 Impact on Reproduction
- Viral Infections and Outbreaks Research
- Pharmaceutical Quality and Counterfeiting
- Pregnancy and Medication Impact
- HIV/AIDS drug development and treatment
- Pharmacological Effects and Toxicity Studies
- Reproductive tract infections research
- HIV, Drug Use, Sexual Risk
- Disaster Response and Management
- Ectopic Pregnancy Diagnosis and Management
- Pharmaceutical studies and practices
- Pregnancy and preeclampsia studies
- Healthcare Policy and Management
- Antibiotic Resistance in Bacteria
- Blood Pressure and Hypertension Studies
- Pharmacovigilance and Adverse Drug Reactions
University of Washington
2016-2025
Seattle University
2012-2025
Seattle Public Schools
2017-2025
Institute for Health Metrics and Evaluation
2017-2024
Weatherford College
1997-2023
Microsoft (United States)
2023
Center for Global Health
2008-2019
Health Alliance International
2016
MRC Unit the Gambia
2015
American Pharmacists Association Foundation
2013-2014
Chlamydia trachomatis is a frequent cause of pelvic inflammatory disease. However, there little information from clinical studies about whether screening women for cervical chlamydial infection can reduce the incidence this serious illness.
Antimicrobial resistance (AMR) is a serious threat to global public health. WHO emphasises the need for countries monitor antibiotic consumption combat AMR. Many low-income and middle-income (LMICs) lack surveillance capacity; we aimed use multiple data sources statistical models estimate consumption.In this spatial modelling study, used individual-level from household surveys inform Bayesian geostatistical model of usage in children (aged <5 years) with lower respiratory tract infections...
Antimicrobial resistance (AMR) is an urgent global health challenge and a critical threat to modern care. Quantifying its burden in the WHO Region of Americas has been elusive—despite region’s long history surveillance. This study provides comprehensive estimates AMR assess this growing threat. We estimated deaths disability-adjusted life-years (DALYs) attributable associated with for 23 bacterial pathogens 88 pathogen–drug combinations countries 2019. obtained data from mortality...
<h2>Summary</h2><h3>Background</h3> Despite a global epidemiological transition towards increased burden of non-communicable diseases, communicable diseases continue to cause substantial morbidity and mortality worldwide. Understanding the wide range infectious its variation by geography age, is pivotal research priority setting resource mobilisation globally. <h3>Methods</h3> We estimated disability-adjusted life-years (DALYs) associated with 85 pathogens in 2019, globally, regionally, for...
Preliminary animal and human data suggest that estrogens may be protective against Alzheimer's disease in women. In a population-based case-control study at Group Health Cooperative of Puget Sound, Seattle, Washington, the authors compared exposure estrogen replacement therapy 107 female cases with 120 age- sex-matched controls by using computerized pharmacy data. The were obtained from Disease Patient Registry University which is based on enumerated health plan population 1987 to 1992....
This study analyzed how the use and cost of pharmaceuticals varied by level drug co-payment in a staff model health maintenance organization (HMO). An historical cohort design was used to changes utilization costs 19,982 continuously enrolled beneficiaries less than age 65. The initially had no co-payments, but experienced rates $1.50, $3.00, $3.00 plus other benefit during three-year period. A comparison 23,164 selected from same setting who were subject time Data on medications obtained an...
We determined the prevalence of certain major congenital disorders among infants women who used a wide variety drugs during first trimester pregnancy in prepaid health plan which automated recording prescriptions filled and diagnosed at birth was available. No strong associations between any commonly studied were present. (<i>JAMA</i>1981;246:343-346)
Falsified and substandard drugs are a global health problem, particularly in low- middle-income countries (LMIC) that have weak pharmacovigilance drug regulatory systems. Poor quality medicines important consequences, including the potential for treatment failure, development of antimicrobial resistance, serious adverse reactions, increasing healthcare costs undermining public's confidence This article presents review methods employed analysis pharmaceutical formulations. Technologies...
Standardized monitoring of antibiotic use underpins the effective implementation antimicrobial stewardship interventions in combatting resistance (AMR). To date, few studies have assessed hospitals Uganda to identify gaps that require intervention. This study applied World Health Organization's standardized point prevalence survey methodology assess 13 public and private not-for-profit across country. Data for 1077 patients 1387 prescriptions were collected between December 2020 April 2021...
Abstract Background Antimicrobial resistance (AMR) is a global health security threat and associated with increased morbidity mortality. One of the key drivers AMR inappropriate use antibiotics. A component improving antibiotic conducting antimicrobial (AMU) surveillance. Methods USAID Medicines Technologies Pharmaceutical Services Program has supported implementation stewardship activities, including setting up systems for AMU surveillance in Tanzania Uganda. Results from both countries...
Abstract Pharmacies are important health care access points, but no national map currently exists of where pharmacy deserts located. This cross-sectional study used address data and Census Bureau surveys to define at the census tract level in all 50 US states District Columbia. We also compared sociodemographic characteristics desert vs non-pharmacy communities. Nationally, 15.8 million (4.7%) people United States live deserts, spanning urban rural settings states. On average, communities...
The authors used cell cultures to assess the prevalence of cervical infection caused by Chlamydia trachomatis in a population-based sample nonpregnant women aged 15 34 years who attended two primary care clinics at Group Health Cooperative Puget Sound, Seattle, Washington, between January 1, 1988, and June 30, 1989. C. was isolated from 67 1,804 (3.7%), including 13% those were less than 20 age. Seven patient characteristics independently predictive chlamydial stepwise multivariate logistic...
Abstract Purpose To identify and characterize risk factors for rhabdomyolysis in patients prescribed statin monotherapy or plus fibrate therapy. Methods A nested case‐control study was conducted within a cohort of 252 460 new users lipid‐lowering medications across 11 geographically dispersed U.S. health plans. Twenty‐one cases confirmed by medical record review were compared to 200 individually matched controls without rhabdomyolysis. conditional logistic regression model applied evaluate...
Background As pre-exposure prophylaxis (PrEP) becomes more widely used in heterosexual populations, an important consideration is its safety infants who are breastfed by women taking PrEP. We investigated whether tenofovir and emtricitabine excreted into breast milk then absorbed the breastfeeding infant clinically significant concentrations when as PrEP lactating women. Methods Findings conducted a prospective short-term, open-label study of daily oral emtricitabine–tenofovir disoproxil...
Objective To delineate the prevalence and factors associated with antimicrobial use across six referral hospitals in Tanzania using WHO point survey (PPS) methodology to inform hospital-specific stewardship programmes. Design Cross-sectional analytical study. Setting Six Tanzania. Participants Patients irrespective of age gender (n=948) admitted hospital wards before 8:00 hours on each day were included December 2019. Using PPS methodology, data hospitals, wards, patients, antibiotics,...