A5072435982- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Nutrition and Health in Aging
- Body Composition Measurement Techniques
- Helicobacter pylori-related gastroenterology studies
- HIV-related health complications and treatments
- Systemic Lupus Erythematosus Research
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Viral gastroenteritis research and epidemiology
- Galectins and Cancer Biology
- Mosquito-borne diseases and control
- Gastrointestinal disorders and treatments
- Malaria Research and Control
- Clinical Nutrition and Gastroenterology
- Empathy and Medical Education
- Hepatitis Viruses Studies and Epidemiology
- Patient-Provider Communication in Healthcare
- Viral Infections and Vectors
- Diabetes Management and Education
- Health, Nursing, Elderly Care
- Patient Safety and Medication Errors
- Geography and Environmental Studies
Universidade Federal de Minas Gerais
2015-2024
Hospital das Clínicas da Universidade Federal de Minas Gerais
2011-2022
University of Maryland, Baltimore
2022
National Institutes of Health
2022
Fundação Faculdade de Medicina
2022
Ministério da Saúde
2015
Financiadora de Estudos e Projetos
2002
Fundação de Amparo à Pesquisa do Estado de Minas Gerais
2002
Fundação Hospitalar do Estado de Minas Gerais
1999
In Brazil, dengue epidemics erupt sporadically throughout the country and it is unclear if outbreaks may initiate a sustainable transmission cycle. There are few studies evaluating ability of Brazilian Aedes aegypti populations to transmit virus (DENV). The aim this study was compare DENV susceptibility field-captured Ae. from nine distinct geographic areas city Belo Horizonte in 2009 2011. Infection Rate (IR), Vector Competence (VC) Disseminated (DIR) were determined. eggs each region...
Abstract Background Preserved skeletal muscle is essential for the maintenance of healthy bone. Loss bone mineral density (BMD) and strength, considered a predictor BMD, have been demonstrated in patients with cirrhosis, but they are poorly studied chronic hepatitis C (CHC) without cirrhosis. Thus, we aimed to evaluate prevalence low BMD its association body composition, nutritional status CHC. Methods One hundred four subjects [mean age, 50.5 ± 11.3 years; 75.0% males; 67.3% non‐cirrhotic;...
Summary We evaluated the role of family in transmission Helicobacter pylori infection preschool‐aged children from a rural district State Minas Gerais, Brazil. Sixty‐six families (66 index children, 63 mothers, 60 fathers and 134 siblings), defined as at least one parent living same household with offspring up to 8 years old, were studied. Odds ratios (OR) 95% confidence intervals (CI) estimated by logistic regression controlling for age, gender, number H. status father, mother siblings. The...
Although no regimen can eradicate in 100% of patients, factors that may affect the eradication rates have been poorly studied.To evaluate associated with treatment failure.One hundred patients were treated pantoprazole plus clarithromycin and furazolidone for eradication. Clarithromycin resistance was evaluated by agar dilution method. Point mutations 23S rRNA genes related to investigated polymerase chain reaction restriction length fragment polymorphism A reaction. The data analyzed...
The present study aimed to provide a molecular characterization of circulating rotavirus (RVA) strains in Rio Branco, Acre, the post‐rotavirus vaccination period, particularly with regard emerging, increasingly prevalent G12P[8] genotype. A total 488 fecal specimens from diarrheic and non‐diarrheic children were obtained between January December 2012. RVA detection was initially performed using enzyme‐linked immunosorbent assay (ELISA) method, followed by reverse‐transcription polymerase...
Summary Background Results of studies evaluating the effect viral eradication following direct‐acting antiviral (DDA) therapy on skeletal muscle mass patients with chronic hepatitis C (CHC) are scarce. Aim To assess components sarcopenia (low mass, low strength and physical performance) in a cohort CHC individuals before after DAA therapy. Methods We performed longitudinal study who underwent body composition assessment (T0), at 12 (T1) 48 (T2) weeks DDA Bioelectrical Impedance Analysis was...
Because cirrhotic patients are at high risk of malnutrition and sarcopenia, we evaluated the prevalence low fat-free mass index (FFMI) phase angle (PhA) among with chronic hepatitis C (CHC).In total, 135 subjects CHC (50.4% males; mean age, 52.4 ± 11.8 years; 65.9% noncirrhotic 34.1% compensated patients) were prospectively included by bioelectrical impedance analysis. Subjective global assessment was used to evaluate malnutrition.Low FFMI PhA identified in 21.5% 23.7% patients,...
Objective: Patients with chronic hepatitis C (CHC) have a poorer quality of life than those other liver diseases. However, some the factors that determine health-related (HRQOL) in these patients, such as degree fibrosis, are still controversial. Therefore, aim present study was to investigate impact CHC on HRQOL by conducting clinical, psychiatric, and sociodemographic evaluations. Methods: One hundred twenty-four consecutive patients attending referral center for were evaluated using...
Brazil reported the majority of dengue cases in Americas during last two decades, where occurrence human is exclusively attributed to Aedes (Stegomyia) aegypti (Linnaeus). Nowadays, other recognized Dengue virus (DENV) vector Asian countries, albopictus (Skuse), has been detected more than half 5565 Brazilian municipalities. Therefore, aim present study was investigate presence of, and determine Ae. albopictus' dynamics influenced by spatiotemporal characteristics a dengue-endemic risk city...
Abstract Background There is neither a gold standard definition nor universal consensus to diagnose sarcopenia in patients with chronic hepatitis C. Thus, we aimed compare the prevalence of and agreement discrepancies between European Working Group on Sarcopenia Older People (EWGSOP1), EWGSOP2, Foundation for National Institutes Health Biomarkers Consortium Project (FNIH) definitions Methods Dual‐energy x‐ray absorptiometry was used assess muscle mass by quantifying appendicular lean (ALM)...
The hypothesis that Helicobactermight be a risk factor for human liver diseases has arisen after the detection of Helicobacter DNA in hepatic tissue patients with hepatobiliary diseases. Nevertheless, no explanation justifies presence bacterium been proposed. We evaluated Helicobacterin different aetiologies. prospectively 147 (106 primary and 41 metastatic tumours) 20 donors as controls. species were investigated by culture specific 16S rDNA nested-polymerase chain reaction followed...
Chronic hepatitis B (CHB) and schistosomiasis are prevalent in several countries, but the impact of this association is unknown. We aimed to investigate prevalence morbidity co-infection Minas Gerais, an endemic area Brazil.In total, 406 adults with CHB (HBsAg positive >6 months) were included a cross-sectional study. was classified as replicative (HBV DNA ≥ 2.000 IU/ml), low or inactive carriers <2.000 IU/ml). Schistosomiasis confirmed by epidemiological clinical records. Liver biopsies...
Objective: Nutrition disorders in patients with chronic liver disease have become a recent concern because these influence outcomes. We investigated patients' nutrition status, included consecutively the last 2 years to study, and related results severity of disease. Methods : A total 230 hepatitis B (n = 80) or C 150) were evaluated by subjective global assessment (SGA) body mass index (BMI). The risk metabolic complications was assessed waist circumference (WC) percentage fat (%BF)....
In this study, strategies for serum biomarker assessment were developed therapeutic monitoring of HCV patients. For purpose, chemokine/cytokine levels measured by cytometric-bead-array in patients, categorized according to immunotherapy response as: non-responder/NR, relapser/REL and sustained-virologic-responder/SVR. The results demonstrated an overall increase general, failure was associated with presence a predominant baseline proinflammatory pattern enhanced CCL5/RANTES, IFN-α, IFN-γ...
Although the prognostic relevance of sarcopenia has been increasingly recognised in context liver disease, there is a paucity data evaluating body composition patients with chronic hepatitis B (CHB). Beyond virus-related factors, nutritional and metabolic aspects can be associated skeletal muscle abnormalities these should not disregarded.To evaluate association between components demographic, clinical, lifestyle, nutritional, biochemical variables CHB patients.Dual-energy X-ray...
Merleau-Ponty innovated when giving primacy to the body and perception in his philosophical proposal. Within field of health, thinking gives us access knowledge gained from corporeality individuals with chronic diseases. The objective this study was expand understanding phenomena associated daily use medication, which includes increasingly complex drug regimes, through lens Merleau-Ponty. To end, we described research steps anchored phenomenological philosophy structured them form a cascade,...
•HDL cholesterol levels <60 mg/dL were independently associated with necroinflammatory activity in chronic hepatitis C (CHC). •CHC patients hypertension are at an increased risk of developing activity. •In CHC, liver fibrosis was old age, steatosis, and HDL-C mg/dL. •Triglycerides ≥150 lobular inflammatory CHC. Background - Approximately 71 million people chronically infected virus (HCV) worldwide. A significant number these individuals will develop cirrhosis and/or hepatocellular carcinoma....