A5100372756- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Microscopic Colitis
- Streptococcal Infections and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Diphtheria, Corynebacterium, and Tetanus
- Gut microbiota and health
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Salmonella and Campylobacter epidemiology
- Escherichia coli research studies
- Mosquito-borne diseases and control
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Toxin Mechanisms and Immunotoxins
- Veterinary Medicine and Surgery
- Microbial infections and disease research
- Enterobacteriaceae and Cronobacter Research
- Animal health and immunology
- Malaria Research and Control
- Viral Infections and Vectors
- Rabies epidemiology and control
- Cardiac Structural Anomalies and Repair
- Leptospirosis research and findings
- Nosocomial Infections in ICU
Universidade Federal de Minas Gerais
2016-2025
Baylor College of Medicine
2024
Texas Children's Hospital
2021-2024
Hospital Braga
2022-2024
Universidade Federal de Goiás
2020-2024
Universidade Federal do Pará
2024
International Olive Council
2016-2024
Invictus Medical (United States)
2024
Vodafone (Portugal)
2023
Fundação Oswaldo Cruz
2013-2023
Rheumatic heart disease (RHD) remains a public health issue in low- and middle-income countries (LMICs). However, there are few large studies enrolling individuals from multiple endemic countries.
Salmonella Dublin is a serovar that causes severe infections and cattle. Despite the importance of this agent, research on achieving its elimination from dairy farms limited, which complicates risk mitigation control efforts. This study thus aimed to assess prevalence S . farm with history outbreaks, understand dynamics infection, characterize antimicrobial resistance isolates, evaluate their genetic similarity. Multiparous cows in postpartum phase are nearly five times more likely shed sp....
Staphylococcus pseudintermedius is a major commensal bacterium of the skin and mucosae dogs an opportunistic agent responsible for several clinical infections, such as pyoderma, otitis, surgical wound infections. The emergence methicillin-resistant S . (MRSP) has become problem great concern in veterinary human medicine because it multidrug resistant (MDR) can also infect humans. This study aimed to identify occurrence spp. infected patients investigate antimicrobial resistance profiles...
Enterotoxemia, a disease that affects domestic ruminants, is caused mainly by the epsilon toxin from Clostridium perfringens type D. Its eradication virtually impossible, control and prophylaxis are based on systematic vaccination of herds with toxoids efficient in inducing protective antibody production. The use recombinant toxins one most promising these strategies. This work evaluates potency Cl. D toxoid expressed Escherichia coli administered to goats, sheep, cattle. etx gene was cloned...
Toxin detection and screening could contribute to knowledge of the transmission patterns, risk factors epidemiology Clostridium difficile perfringens.To isolate C. perfringens detect A/B toxins in faecal samples from diarrhoeic nondiarrhoeic foals.Cross-sectional observational study.A total 153 foals were collected: 139 farms 14 admitted a veterinary hospital. The detected by cytotoxicity assay. All suspected colonies subjected polymerase chain reaction for major toxin genes (α, β, ε ι) β2-,...
The present study aimed to explore the motivations of Brazilian dog owners and their knowledge about risks related raw meat-based diets (RMBD) as well evaluate important enteropathogens such Salmonella spp., C. perfringens, difficile, in feces dogs fed different diets. majority pet (69.3%) reported have chosen this diet for dogs, considering it be more "natural". A large number declared that RMBD do not pose health animals (87.9%) or humans (98.8%), even though almost one third respondents...
ABSTRACT: Infections by Staphyloccocus pseudintermedius in the skin of dogs have been object studies, since such microorganisms often present multiple resistance to antibiotics. This study aimed identify and evaluate antimicrobial susceptibility Staphylococcus (SP) strains isolated from with otitis. Swabs both ears 52 otitis (n=104) were included. Bacteria cultured using Muller-Hinton agar (supplemented 5% equine blood incubated at 37°C for 24 48 hours. All colonies underwent biochemical...
Considering the increasing popularity of reptiles as pets and their possible role reservoirs pathogenic microorganisms, aim this study was to isolate Escherichia coli, Salmonella spp., Clostridium perfringens, C. difficile strains from in Brazil characterize isolated strains. The characterization based on phylogenetic typing E. identification virulence genes difficile, serotyping ribotyping MLST antimicrobial susceptibility test Cloacal swabs were collected 76 reptiles, which 15 lizards, 16...
Clostridium perfringens is a normal inhabitant of the intestinal tract chickens as well potential pathogen that causes necrotic enteritis and colangio hepatitis. The minimum inhibitory concentration (MIC) seven different compounds used for therapy, growth promotion or prevention coccidiosis was determined by agar dilution method 55 C. strains isolated from intestines broiler chickens. All showed high susceptibility to penicillin, avilamycin, monensin narasin. Only 7.3% an intermediated...
Clostridium difficile has emerged as a major cause of neonatal colitis in piglets, displacing classic bacterial pathogens. However, there is no information regarding the distribution this microorganism pig farms Brazil. In present study, presence toxins A/B and C. strains stool samples from 60 diarrheic or non-diarrheic newborn piglets (one to seven days old), 15 different farms, was studied. The detected by ELISA PCR used identify toxin A, B binary gene each isolated strain. were ten...
The objective of this study was to detect C. difficileA/B toxins and isolate strains perfringensand difficile from diarrheic non-diarrheic dogs in Brazil. Stool samples were collected 57 dogs, 35 which apparently healthy, 22 diarrheic. detected by ELISA, difficilewere identified multiplex PCR. 21 (36.8%). Of these, 16 (76.2%) five (23.8%) dogs. Twelve (21.1%) isolated, ten A+B+and two A-B-. All non-toxigenic isolated animals. binary toxin gene cdtBwas found one strain, derived a dog....
Clostridium difficile is an emerging enteropathogen responsible for pseudomembranous colitis in humans and diarrhoea several domestic wild animal species. Despite its known importance, there are few studies about C. polymerase chain reaction (PCR) ribotypes Brazil the actual knowledge restricted to on human isolates. The aim of study was therefore compare isolated from animals Brazil. Seventy-six strains (n = 25), dogs 23), piglets 12), foals 7), calves one cat, manned wolf were distributed...
Due to the increasingly restricted use of antimicrobials in animal production systems, prevention and control Clostridium perfringens type A- C-induced diarrhea piglets should be based on passive immunization via prepartum vaccination sows. Given current obstacles conventional clostridial vaccines, recombinant proteins has been considered represent a promising alternative. In present study, neutralizing antibody response immunized sows their litters bivalent vaccine containing C. toxoids...
A obesidade configura-se como uma condição multifatorial complexa, influenciada por aspectos genéticos, fisiológicos, ambientais e psicológicos, resultando no acúmulo excessivo de tecido adiposo. Este estudo transversal, caráter descritivo, analítico retrospectivo, investigou a presença sobrepeso em 300 pacientes, meio da análise dados secundários extraídos Formulários Avaliação Nutricional utilizados nos atendimentos acompanhamentos realizados na Clínica Escola Nutrição do Centro Acadêmico...
Neonatal diarrhea causes significant economic losses in swine production by reducing average daily weight gain (ADWG) and increasing piglet mortality, with Clostridioides difficile (CD) Clostridium perfringens type A (CPA) being the most common causes. The aim of this study was to evaluate efficacy a new commercial vaccine against these agents minimize diarrhea, pre-weaning its negative consequences on performance suckling piglets under field conditions. consisted two randomized,...
Context: Aortic stenosis (AS) induces ventricular remodeling. After surgical aortic valve replacement (SAVR), there is reverse remodeling (RR) that might impact patients’ prognosis. Aims: This study aims to characterize cardiac RR post-SAVR, determine possible explanatory factors of this phenomenon, and assess its prognostic impact. Methods: A retrospective observational 114 patients with severe AS who underwent SAVR between 2017 2021 had echocardiographic follow-up 1 year after. descriptive...
Epsilon toxin produced by Clostridium perfringens types B and D causes enterotoxemia in sheep, goats calves.Enterotoxemia can cause acute or superacute disease, with sudden death of the affected animal.It provokes huge economic losses when large numbers livestock are affected.Therapeutic intervention is challenging, because disease progresses very rapidly.However, it be prevented immunization specific immunogenic vaccines.We cloned etx gene, encoding epsilon toxin, into vector pET-11a;...