A5004205436- Meta-analysis and systematic reviews
- Lysosomal Storage Disorders Research
- Hepatitis B Virus Studies
- Reproductive System and Pregnancy
- Hepatitis C virus research
- Studies on Chitinases and Chitosanases
- Endometriosis Research and Treatment
- Neonatal Respiratory Health Research
- Trypanosoma species research and implications
- Electronic Health Records Systems
- scientometrics and bibliometrics research
- Birth, Development, and Health
- COVID-19 Clinical Research Studies
- Health Sciences Research and Education
- Health and Medical Research Impacts
- Effects and risks of endocrine disrupting chemicals
- Genetics, Bioinformatics, and Biomedical Research
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Social Media in Health Education
- Molecular Biology Techniques and Applications
- Neonatal Health and Biochemistry
- Innovations in Medical Education
- Endometrial and Cervical Cancer Treatments
- Multi-Criteria Decision Making
Iuliu Hațieganu University of Medicine and Pharmacy
2015-2024
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2011
Institute for Medical Informatics and Biostatistics
2003
ABSTRACT Hepatitis D virus (HDV) is a satellite of hepatitis B (HBV) for transmission and propagation infects nearly 20 million people worldwide. The HDV genome compact circular single-stranded RNA with extensive intramolecular complementarity. Despite its different epidemiological pathological patterns, the variability geographical distribution are limited to three genotypes two subtypes that have been characterized date. Phylogenetic reconstructions based on delta antigen gene full-length...
Hepatitis delta virus (HDV) is responsible for the most severe form of acute and chronic viral hepatitis. We previously proposed that Deltavirus genus composed eight major clades. However, few sequences were available to confirm this classification. Moreover, little known about structural functional consequences HDV variability. One practical consequence failure quantification assays properly detect or quantify plasmatic RNA. Between 2001 2014, 2,152 strains prospectively collected genotyped...
The aim of the study was to investigate serum pro-inflammatory cytokine profile in patients with diagnosed endometriosis.The included 160 women, who were divided two groups (Group I - endometriosis; Group 2 healthy). We evaluated levels interleukin (IL)-1β, IL-5, IL-6, IL-7, and IL-12, tumour necrosis factor α (TNF-α) use Human Multiplex Cytokine Panels.The level IL-1β, TNF-α is significantly higher women endometriosis compared free disease, from control group (mean 10.777, 183.027, 131.326,...
The glycation process is involved in both the intrinsic (individual, genetic) and extrinsic (ultraviolet light, polution lifestyle) aging processes, can be quantified at epidermal or dermal level by histological, immunohistochemical (IHC), imagistic methods. Our study focused on a histological immunohistological comparison of sun-protected regions versus sun-exposed from different age groups skin phototype III subjects, related to process. Skin samples collected non-protected UV protected...
Abstract The estrogenic and anti‐estrogenic effects of butylparaben (BuPB), butylated hydroxyanisole (BHA), hydroxytoluene (BHT) propyl gallate (PG) were evaluated for individual compounds as well binary mixtures, using an estrogen‐dependent reporter gene assay in T47D‐Kbluc breast cancer cells proliferation MCF‐7 cells. In terms estrogenicity the potency selected increased from BHA < PG BuPB luciferase (with BHT showing no significant activity), while following order was observed:...
Endometriosis is a frequent gynecologic disease with severe impact on the quality of life in affected women; its pathogenesis yet to be fully understood, an altered immunity as possible key factor. The present study aimed investigate serum anti-inflammatory cytokine profile patients endometriosis compared healthy controls.One hundred and sixty women were included, divided into two groups (Group I - endometriosis; Group 2 women). We evaluated levels interleukin-1 receptor antagonist (IL-1Ra),...
Background: Health-related quality of life (HRQL) and voice handicap index (VHI) laryngectomies seem to be relevant regarding rehabilitation. The aim this study is assess the impact on HRQL VHI laryngectomies, following Materials Methods: A retrospective done at Ear, Nose, Throat Department Emergency County Hospital. Sixty-five laryngectomees were included in study, which 62 them underwent Voice QOL assessed using questionnaires developed by European Organisation for Research Treatment...
BACKGROUND:Retinopathy is a serious complication related to prematurity and leading cause of childhood blindness. The aggressive posterior form retinopathy (APROP) has worse anatomical functional outcome following laser therapy, as compared with the classic disease. main measures are APROP regression rate, structural outcomes, complications associated intravitreal bevacizumab (IVB) versus photocoagulation in APROP. MATERIAL AND METHODS:This retrospective case series that includes infants who...
Hepatitis delta virus (HDV) increases morbidity in B (HBV)-infected patients. In the mid-eighties, an outbreak of HDV fulminant hepatitis (FH) Central African Republic (CAR) killed 88% patients hospitalized Bangui. We evaluated infections with HBV and among students pregnant women, 25 years after to determine (i) prevalence infection this population, (ii) clinical risk factors for and/or infections, (iii) characterize compare strains from FH 1980s 2010 HBV–HDV strains. performed a cross...
Purpose . This study aims to evaluate the regression of retinopathy prematurity (ROP) after one intravitreal injection bevacizumab and factors that influenced it. Methods retrospective case series was carried out at “Iuliu Hațieganu” University Medicine Pharmacy, Cluj-Napoca, Romania. It includes all consecutive infants treated for ROP with injection, from January 1, 2009, throughout July 31, 2013. The follow-up continued 60 weeks injection. We recorded classification, regression, gender,...
Abstract Aim: This study assesses the value of intraplacental vascularization indices, determined by three-dimensional (3D) power Doppler ultrasound, in evaluation placental circulation. A prospective has been conducted on two groups pregnant women. Group I included women with a normal evolution pregnancy, whereas group II consisted preeclampsia. The subjects were assessed ultrasound between 28 th and 38 week amenorrhea. Intraplacental was studied 3D ultrasound. indices calculated using...
Background/aim: The aim of the study was to evaluate serum concentration main chemokines and interferons in patients with diagnosed endometriosis. Materials methods: A total 160 women were divided two groups (group 1 - endometriosis; group 2 healthy women). Serum levels IFN-α, IFN-γ, MCP-1, MIP-1α, MIP-1β, RANTES, eotaxin, IL-8, MIG, IP-10, IL-17A measured Human Multiplex Cytokine Panels. Results. IL-8 significantly higher (mean 14.03, 57.24, 534.24, respectively, compared 0.58, 20.51,...
Multiple sclerosis (MS) is a common neurological disease affecting the optic nerve, directly or indirectly, through transsynaptic axonal degeneration along visual pathway. New ophthalmological tools, arguably most important being optical coherence tomography (OCT), could prove paramount in redefining MS diagnoses and shaping their follow-up protocols, even when nerve not involved.A prospective clinical study was conducted. In total, 158 eyes from patients previously diagnosed with relapsing...
To assess the neonatal outcomes in newborns with intrauterine growth restriction (IUGR) a Romanian population 3 level maternity unit.A matched case-control design, one control for each patient was used. The case group comprised neonates birth weight and length below 10th percentile gestational age. Individual matching by gender age of gestation used to identify group. Both cases controls were selected from infants admitted discharged Neonatal Ward, at First Gynecology Clinic, County...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Malutan A, Drugan C, T, Ciortea R, Mihu D. The association between interleukin-4 -590C/T genetic polymorphism, IL-4 serum level, and advanced endometriosis. Central European Journal of Immunology. 2016;41(2):176-181. doi:10.5114/ceji.2016.60992. APA Malutan, A., Drugan, C., T., Ciortea, R., & Mihu, (2016). Immunology, 41(2), 176-181. https://doi.org/10.5114/ceji.2016.60992 Chicago Andrei M., Cristina Tudor...
The chronic complications of diabetes mellitus (DM) are accompanied by inflammatory manifestations. Our study aimed to evaluate a possible association between the status (reflected serum chitotriosidase and neopterin) timely evolution occurrence microvascular in patients with type 1 DM. This observational, cross-sectional included 82 DM from Centre for Diabetes, Nutrition Metabolic Diseases, Cluj-Napoca, Romania. results demonstrated link extent inflammation, evaluated enzymatic activity...
Objective Inflammatory bowel diseases are chronic pathologies characterized by a complex interplay of genetic and environmental factors, as well aberrant immune responses. This study aimed to investigate inflammation markers’ seasonality association with disease exacerbation episodes in patients Crohn’s ulcerative colitis. Methods 284 were classified based on clinical, endoscopic, histopathological criteria. Systemic was evaluated using C-reactive protein (CRP), erythrocyte sedimentation...
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), presents diverse clinical manifestations and multi-organ involvement. This study aimed to evaluate the extra-pulmonary histopathological patterns underpinning COVID-19-induced lesions in cardiac, hepatic, renal, brainstem, splenic tissues.
Optical coherence tomography (OCT) is a non-invasive imaging technique based on the principle of low-coherence interferometry that captures detailed images ocular structures. Multiple sclerosis (MS) neurodegenerative disease can lead to damage optic nerve and retina, which be depicted by OCT. The purpose this pilot study determine whether macular OCT used as biomarker in detection retrochiasmal lesions visual pathway MS patients. We conducted prospective we included 52 patients 27 healthy...
Retrograde axonal neurodegeneration along the visual pathway-either direct or trans-synaptic-has already been demonstrated in multiple sclerosis (MS), as well compressive, vascular, posttraumatic lesions of pathway. Optical coherence tomography (OCT) can noninvasively track macular and optic nerve changes occurring a result this phenomenon. Our paper aimed to review existing literature regarding hemimacular atrophic ganglion cell layer identified using OCT examination MS patients without...
This study examines the interplay between human leukocyte antigen (HLA) compatibility and killer-cell immunoglobulin-like receptor (KIR) genotypes in influencing kidney transplantation outcomes. Understanding these interactions is crucial for improving graft survival minimizing rejection risks. We evaluated 84 transplant recipients, dividing them into two groups based on post-transplant outcomes: there were 68 with stable function (SGF) 16 who experienced chronic (CR). Patients selected...