- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Neurogenesis and neuroplasticity mechanisms
- Selenium in Biological Systems
- Ovarian function and disorders
- Curcumin's Biomedical Applications
- Neuroscience and Neuropharmacology Research
- Glycosylation and Glycoproteins Research
- Anesthesia and Neurotoxicity Research
- Pesticide Exposure and Toxicity
- CRISPR and Genetic Engineering
- Nerve injury and regeneration
- Mesenchymal stem cell research
- Alzheimer's disease research and treatments
- Carcinogens and Genotoxicity Assessment
- Pluripotent Stem Cells Research
- Retinoids in leukemia and cellular processes
- Retinal Development and Disorders
- Zebrafish Biomedical Research Applications
- Collagen: Extraction and Characterization
- Biological Activity of Diterpenoids and Biflavonoids
- Chemotherapy-induced organ toxicity mitigation
- Ovarian cancer diagnosis and treatment
- Extracellular vesicles in disease
- COVID-19 Impact on Reproduction
Mashhad University of Medical Sciences
2013-2024
Shahed University
2024
Zanjan University of Medical Sciences
2022-2024
Shahid Rajaee Teacher Training University
2022
Shahid Beheshti University of Medical Sciences
2015-2019
Tehran University of Medical Sciences
2012-2017
Isfahan University of Medical Sciences
2012
Abstract Osteoporosis is a common bone disease that results in elevated risk of fracture, and delayed healing impaired regeneration are implicated by this disease. In study, Elastin/Polycaprolactone/nHA nanofibrous scaffold combination with mesenchymal stem cells were used to regenerate defects. Cytotoxicity, cytocompatibility cellular morphology evaluated vitro observations revealed an appropriate environment for attachment, growth, migration, proliferation provided scaffold. At 3 months...
Recent studies have shown that polycystic ovary syndrome (PCOS) affects about 6% of women worldwide. It is associated with reproductive and metabolic dysfunction. Caffeine naturally found in tea, cocoa, coffee. has been caffeine can change hormonal profiles, stimulate ovulation, enhance fertility. Therefore, this study, the effects on rats PCOS were investigated. For purpose, 40 female divided into five groups: (1) control group (without any intervention), (2) sham (administration olive oil...
Human chorionic mesenchymal stem cells (HCMSCs) have been recognized as a desirable choice for cell therapy in neurological disorders such Parkinson's disease (PD). Due to invaluable features of HCMSCs including their immunomodulatory and immunosuppressive properties, easily accessible less differentiated compared other types MSCs, provide great hope regenerative medicine. Thus, the purpose this study was determine vitro vivo efficacy HCMSCs-derived dopaminergic (DA) neuron-like with regard...
Busulfan (BSU) is a chemotherapeutic drug that can cause subfertility or sterility in males. We investigated the effects of adipose tissue-derived mesenchymal stem cells (AT-MSC) conditioned medium (CM) (AT-MSC-CM) on histopathological and molecular characteristics mouse testes exposed to BSU using stereology. used adult male mice divided randomly into five groups: control, Dulbecco's modified Eagle's (DMEM), dimethyl sulfoxide (DMSO), BSU, + CM. Thirty-five days following injection, sperm...
Silicon dioxide nanoparticles (SiO2-NPs) are among the most widely used because of their chemical-physical properties. Since brain maturation occurs in neonatal period humans and many mammals, it is important to understand how NPs may affect this process. This study tested hypothesis that SiO2-NPs from treated dams could hippocampus rats during lactation. Twenty-four pregnant rats, after delivery, were divided into three groups control, (25 mg/kg) (100 mg/kg). The 2nd 21st days post-delivery...
Insulin is an essential factor that controls female reproductive system. signaling via Foxo1 and Akt1 can improve steroidogenesis, cell proliferation, protein synthesis. We aimed to determine the effect of insulin on possible changes in gene expression, hormonal status, histological aspects ovary following induction animal model polycystic syndrome (PCOS).In this experimental study, 24 adult NMRI mice weighing 25-30 g were randomly placed three groups: control, PCOS (60 mg/kg...
The present study aims to assess the influences of oral methylphenidate on kidney function and structure versus vehicle treatment in adult male rats. In this study, thirty rats equally into two groups divided randomly, among them, MPH has been administered for 21 days, at doses 20 mg/kg, control group received salin. renal, under effect applying quantitative real-time PCR, we analyzed nephrotoxicity-related molecular pathways like autophagy, inflammation, apoptosis. Moreover, levels GSH,...