Xin Xu

ORCID: 0000-0003-0106-5730
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About
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Research Areas
  • Insect-Plant Interactions and Control
  • Plant and animal studies
  • Facial Trauma and Fracture Management
  • Dental Radiography and Imaging
  • Diabetes Management and Education
  • Dental Implant Techniques and Outcomes
  • Machine Learning in Materials Science
  • Peroxisome Proliferator-Activated Receptors
  • Seed Germination and Physiology
  • Trauma and Emergency Care Studies
  • Bioinformatics and Genomic Networks
  • Sarcoidosis and Beryllium Toxicity Research
  • Parathyroid Disorders and Treatments
  • Insect symbiosis and bacterial influences
  • Digestive system and related health
  • Protein Structure and Dynamics
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Anaerobic Digestion and Biogas Production
  • Health Literacy and Information Accessibility
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Phagocytosis and Immune Regulation
  • Plant Molecular Biology Research
  • Machine Learning in Bioinformatics
  • Insect and Pesticide Research
  • Cytokine Signaling Pathways and Interactions

Wuhan University of Science and Technology
2025

Research Institute of Resource Insects
2023-2025

Chinese Academy of Forestry
2022-2025

First Affiliated Hospital of Guangzhou Medical University
2022-2023

State Key Laboratory of Respiratory Disease
2022-2023

Guangzhou Medical University
2022-2023

Shandong University
2022

Southern Medical University
2022

Nanfang Hospital
2022

Mongolian University of Science and Technology
2022

Increased apoptosis of alveolar epithelial cells is a prominent feature pulmonary fibrosis. Macrophage efferocytosis, phagocytosis apoptotic by macrophages, crucial for maintaining tissue homeostasis. Expression Mer tyrosine kinase (MERTK, an important recognition receptor in efferocytosis) macrophages thought to be associated with However, how macrophage MERTK affects fibrosis and whether it depends on efferocytosis are not yet clear. Here, we found elevated expression lung from IPF...

10.1186/s12931-023-02424-3 article EN cc-by Respiratory Research 2023-04-29

The horned-gall aphid, Schlechtendalia chinensis, is the most economically valuable Chinese gallnut aphid species, playing a decisive role in production of gallnuts. method cultivating species with artificial moss and increasing yield gallnuts after inoculation has been applied main producing areas However, it still unclear whether cultivation affects fecundity gall-forming effect S. chinensis. In this study, autumn migrant aphids chinensis from wild, introduced populations were used as...

10.3390/insects16010100 article EN cc-by Insects 2025-01-18

For the purpose of developing new drugs and repositioning existing ones, accurate drug-target affinity (DTA) prediction is essential. While graph neural networks are frequently utilized for DTA prediction, it difficult single-scale to access global structure compounds. We propose a novel model in this study, MAPGraphDTA, which uses an approach based on multi-head linear attention mechanism that aggregates features weights multi-scale gated power captures multi-hop connectivity relationships...

10.1371/journal.pone.0315718 article EN cc-by PLoS ONE 2025-02-21

Introduction It remains a big challenge to identify patients who are at high risk of developing severe acute kidney injury (AKI) after cardiac surgery. This study investigated the clinical utility urinary cytokeratin 20 (uCK20), novel biomarker reflecting severity histological tubular injury, for identifying AKI. Methods prospective multicenter cohort enrolled Test set comprising 413 underwent surgery in 5 centers and Validation enrolling 131 an external center. uCK20 six reported renal...

10.1159/000546159 article EN American Journal of Nephrology 2025-05-03

Drug-target interactions (DTIs) play a critical role in drug discovery and repurposing. Deep learning-based methods for predicting drug-target are more efficient than wet-lab experiments. The extraction of original substructural features from drugs proteins plays key enhancing the accuracy DTI predictions, while integration multi-feature information effective representation interaction data also impact precision forecasts. Consequently, we propose prediction model, SSCPA-DTI, based on...

10.1371/journal.pone.0324146 article EN cc-by PLoS ONE 2025-05-30

Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal fibrotic disease with unknow etiology. Owing to lack of reliable prognostic biomarkers effective treatment measures, patients IPF usually exhibit poor prognosis. The aim this study establish risk score model for predicting the prognosis based on autophagy-related genes. Methods GSE70866 dataset was obtained from gene expression omnibus (GEO) database. genes were collected Molecular Signatures Database...

10.3389/fimmu.2022.997138 article EN cc-by Frontiers in Immunology 2022-09-20

BACKGROUNDIdentifying patients with acute kidney injury (AKI) at high risk of chronic disease (CKD) progression remains a challenge.METHODSKidney transcriptome sequencing was applied to identify the top upregulated genes in mice AKI. The product top-ranking gene identified tubular cells and urine mouse human Two cohorts prehospitalization estimated glomerular filtration rate (eGFR) ≥ 45 mL/min/1.73 m2 who survived over 90 days after AKI were used derive validate predictive models. AKI-CKD...

10.1172/jci.insight.180326 article EN cc-by JCI Insight 2024-05-28

In general, insects grow (increase in body size) through molting. To the opposite, size of males horned gall aphid, Schlechtendalia chinensis, gets smaller after molting and as they age. understand molecular bases this rare phenomenon, transcriptomes were generated from 1-5 days old male data analyzed via a weighted gene co-expression network analysis (WGCNA). A total 15 partitioned modules with different topological overlaps obtained, four identified highly significant for length (p <...

10.3389/fphys.2023.1097317 article EN cc-by Frontiers in Physiology 2023-02-06

A new species of gall-forming aphid from China, Qiao jinshaensis gen. et sp. nov., is described Rhus wilsonii Hemsl. Morphological identification and molecular analyses both support the establishment a genus. diagnosis combining morphological characters alate viviparae provided specimen metadata are published in an open-access machine-readable format.

10.3390/insects13121104 article EN cc-by Insects 2022-11-30

HIGHLIGHTS● Potassium-rich mining waste addition can improve the mineral nutrient of traditional sludge fertilizer.● air permeability compost, promote reproduction thermophilic bacteria and shorten composting period.● is beneficial to broaden application sewage fertilizer social economic value fertilizer.

10.2139/ssrn.4022062 article EN SSRN Electronic Journal 2022-01-01

Abstract Background Osteogenesis of lateral window sinus elevation surgery is the key to placement subsequent implant, excessive collapse sub-antral space may adversely affect long-term stability implants. At present, few studies focus on influence contact area osteogenesis. This study evaluated whether change in with maxillary bone and Schneiderian membrane can Methods Cone beam computed tomography (CBCT) images were collected patients requiring floor (residual height &lt; 6 mm) for...

10.21203/rs.3.rs-2317895/v1 preprint EN cc-by Research Square (Research Square) 2022-12-09

Abstract Background Osteogenesis of lateral window sinus elevation surgery is the key to placement subsequent implant, excessive collapse sub-antral space may adversely affect long-term stability implants. At present, few studies focus on influence contact area osteogenesis. This study evaluated whether change in with maxillary bone and Schneiderian membrane can Methods Cone beam computed tomography (CBCT) images were collected patients requiring floor (residual height &lt; 6 mm) for...

10.1186/s12903-022-02694-1 article EN cc-by BMC Oral Health 2022-12-28

Abstract Background Diabetic retinopathy (DR) is a major diabetes-related disease linked to metabolism. However, scientifically assessment of serum metabolic alterations in DR scarce. We aimed investigate the changes coregulation from type 2 diabetic patients (T2DM) and identify corresponding metabolite predictors via widely targeted metabolomics approach. Methods In this case-control study, we tested 613 metabolites 69 pairs T2DM with (case) propensity score-matched without (control)...

10.21203/rs.3.rs-684065/v1 preprint EN cc-by Research Square (Research Square) 2021-07-09
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